| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Monocrotaline perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Monocrotaline_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.257133 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.149989 |
| PM20D1 | peptidase M20 domain containing 1 | 0.136764 |
| GRAMD1B | GRAM domain containing 1B | 0.124669 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.105011 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0982232 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0842783 |
| ASPH | aspartate beta-hydroxylase | 0.0822637 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0817465 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0805579 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0802151 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0688784 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0668623 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0604471 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0601873 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0589656 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0581978 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0581425 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0576405 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0519501 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0516635 |
| BICC1 | BicC family RNA binding protein 1 | 0.0509296 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0507841 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0498483 |
| RTN4 | reticulon 4 | 0.0490092 |
| ENO1 | enolase 1, (alpha) | 0.0486824 |
| RBM39 | RNA binding motif protein 39 | 0.0472108 |
| FGB | fibrinogen beta chain | 0.0469884 |
| WDR43 | WD repeat domain 43 | 0.0461712 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0432881 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0431665 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0424546 |
| TPM3 | tropomyosin 3 | 0.0415252 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0411638 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0410817 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0409089 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0402356 |
| AHNAK | AHNAK nucleoprotein | 0.0402017 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0401872 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0392413 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0392403 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0384929 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0383826 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0377474 |
| TPD52 | tumor protein D52 | 0.0376348 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.037213 |
| CANX | calnexin | 0.0370227 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0366628 |
| EFNA5 | ephrin-A5 | 0.03625 |
| WWOX | WW domain containing oxidoreductase | 0.0361181 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0358037 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0355624 |
| RPL4 | ribosomal protein L4 | 0.0355429 |
| APP | amyloid beta (A4) precursor protein | 0.0353638 |
| PDE8A | phosphodiesterase 8A | 0.034962 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.034875 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0348069 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0346897 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0340054 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.033895 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0338052 |
| TNPO1 | transportin 1 | 0.0334072 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0333838 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0332433 |
| RAD51B | RAD51 paralog B | 0.0329521 |
| THBS1 | thrombospondin 1 | 0.032494 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.032253 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0321878 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0321268 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0319051 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0317208 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0314395 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0314157 |
| ENAH | enabled homolog (Drosophila) | 0.0312518 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0311407 |
| ANLN | anillin, actin binding protein | 0.0310546 |
| FGG | fibrinogen gamma chain | 0.0310022 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0309643 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0306522 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0302726 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0298854 |
| YBX1 | Y box binding protein 1 | 0.0296104 |
| MYOF | myoferlin | 0.0294382 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0293633 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0292737 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0292262 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0288557 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.02864 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0284521 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0276166 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.0273887 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0268984 |
| MKI67 | marker of proliferation Ki-67 | 0.0264678 |
| XPO1 | exportin 1 | 0.0264124 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0263721 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0263557 |
| RRM2 | ribonucleotide reductase M2 | 0.026352 |
| PTMA | prothymosin, alpha | 0.0263197 |
| CALU | calumenin | 0.0261697 |
| NOP58 | NOP58 ribonucleoprotein | 0.0258739 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.187052 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.139098 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.127121 |
| MT2A | metallothionein 2A | -0.126571 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.113795 |
| TMSB10 | thymosin beta 10 | -0.111614 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.105936 |
| IGF2 | insulin-like growth factor 2 | -0.0847175 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.07464 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0745898 |
| PYGL | phosphorylase, glycogen, liver | -0.0691782 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0670139 |
| S100A6 | S100 calcium binding protein A6 | -0.0666098 |
| POTEF | POTE ankyrin domain family, member F | -0.0603804 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0590068 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0559964 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0556416 |
| EGFR | epidermal growth factor receptor | -0.0543825 |
| VIM | vimentin | -0.0542831 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.052189 |
| FLNB | filamin B, beta | -0.0475448 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0447809 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0421076 |
| HLA-B | major histocompatibility complex, class I, B | -0.041871 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0412097 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0408516 |
| NDRG1 | N-myc downstream regulated 1 | -0.0382745 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0381759 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0376055 |
| HLA-A | major histocompatibility complex, class I, A | -0.0340809 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.034051 |
| COPA | coatomer protein complex, subunit alpha | -0.0338071 |
| FTL | ferritin, light polypeptide | -0.0337758 |
| ACTG1 | actin gamma 1 | -0.033486 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0331413 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.031749 |
| STC1 | stanniocalcin 1 | -0.0311287 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0303331 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0288533 |
| KYNU | kynureninase | -0.0284819 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0283065 |
| PFN1 | profilin 1 | -0.0276627 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0273924 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0265417 |
| CMIP | c-Maf inducing protein | -0.0263291 |
| MYO1E | myosin IE | -0.0262358 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0259277 |
| EGR1 | early growth response 1 | -0.0256443 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0252645 |
| KAT6B | K(lysine) acetyltransferase 6B | -0.0245089 |
| ATXN1 | ataxin 1 | -0.0238728 |
| LAMA5 | laminin, alpha 5 | -0.0232815 |
| RPS12 | ribosomal protein S12 | -0.0231865 |
| NUMB | numb homolog (Drosophila) | -0.0230547 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0230458 |
| TPM1 | tropomyosin 1 (alpha) | -0.0227061 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0226481 |
| HM13 | histocompatibility (minor) 13 | -0.0224576 |
| OSMR | oncostatin M receptor | -0.0224542 |
| RPS8 | ribosomal protein S8 | -0.0224032 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0223552 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0223058 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0220195 |
| CD99 | CD99 molecule | -0.0220177 |
| RPS17 | ribosomal protein S17 | -0.0219237 |
| PCNX4 | pecanex 4 | -0.0218986 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0218434 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0216578 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0215384 |
| MAP7 | microtubule-associated protein 7 | -0.0214677 |
| RPS19 | ribosomal protein S19 | -0.0214414 |
| HMGA1 | high mobility group AT-hook 1 | -0.0212383 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0211813 |
| INTS6 | integrator complex subunit 6 | -0.0211352 |
| HMGA2 | high mobility group AT-hook 2 | -0.0211033 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.020719 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0204333 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0204106 |
| CDCP1 | CUB domain containing protein 1 | -0.0201373 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0199755 |
| EXOC6B | exocyst complex component 6B | -0.019859 |
| S100A9 | S100 calcium binding protein A9 | -0.0197523 |
| RPL28 | ribosomal protein L28 | -0.0194925 |
| RPL35A | ribosomal protein L35a | -0.0194168 |
| JUP | junction plakoglobin | -0.019272 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0190694 |
| EHBP1 | EH domain binding protein 1 | -0.0190664 |
| GOLGB1 | golgin B1 | -0.0190638 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0190545 |
| NF1 | neurofibromin 1 | -0.0188157 |
| GPATCH2L | G patch domain containing 2-like | -0.0184954 |
| SLC22A23 | solute carrier family 22, member 23 | -0.018411 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0184082 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0182735 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.018249 |
| RPL37A | ribosomal protein L37a | -0.0182397 |
| SBF2 | SET binding factor 2 | -0.0180412 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0180004 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.017964 |
| ATG7 | autophagy related 7 | -0.017928 |
