| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Monocrotaline perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Monocrotaline_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.106451 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.101315 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0994185 |
| ASPH | aspartate beta-hydroxylase | 0.0923761 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0861294 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0858442 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0848204 |
| ANXA2 | annexin A2 | 0.0752856 |
| ANXA1 | annexin A1 | 0.0740779 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0740778 |
| FTL | ferritin, light polypeptide | 0.0668503 |
| B2M | beta-2-microglobulin | 0.0632427 |
| FAM13A | family with sequence similarity 13, member A | 0.062865 |
| RPS8 | ribosomal protein S8 | 0.062151 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0610399 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0596273 |
| RPS12 | ribosomal protein S12 | 0.0562169 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0557015 |
| TENM3 | teneurin transmembrane protein 3 | 0.0532867 |
| TMSB10 | thymosin beta 10 | 0.0526521 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0518232 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0513124 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0509614 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0502829 |
| NPTN | neuroplastin | 0.0477239 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.047438 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0471091 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0469338 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0458198 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0443315 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0438192 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0437965 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0432912 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0432851 |
| CCNY | cyclin Y | 0.0426702 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0407736 |
| KRT17 | keratin 17, type I | 0.0406923 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0402077 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0395214 |
| RYBP | RING1 and YY1 binding protein | 0.039428 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0391073 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0380068 |
| TOP1 | topoisomerase (DNA) I | 0.0375397 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0372203 |
| PKM | pyruvate kinase, muscle | 0.037146 |
| KYNU | kynureninase | 0.0368007 |
| OGA | O-GlcNAcase | 0.0363931 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0363477 |
| SQSTM1 | sequestosome 1 | 0.0359891 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.035974 |
| UBC | ubiquitin C | 0.0358457 |
| TXNRD1 | thioredoxin reductase 1 | 0.0356208 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0346124 |
| IER3 | immediate early response 3 | 0.0343695 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.034229 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0324311 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0324139 |
| FN1 | fibronectin 1 | 0.032364 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0322943 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0316552 |
| MYOF | myoferlin | 0.031645 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0313324 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0312321 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0308232 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0308073 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0305201 |
| DTNA | dystrobrevin, alpha | 0.0301619 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0297788 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0291821 |
| S100A6 | S100 calcium binding protein A6 | 0.0289942 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0286293 |
| SBF2 | SET binding factor 2 | 0.0283901 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0280821 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.027976 |
| SLTM | SAFB-like, transcription modulator | 0.0279168 |
| SNX9 | sorting nexin 9 | 0.0274983 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0273524 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0271131 |
| SPPL3 | signal peptide peptidase like 3 | 0.0270192 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0265705 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0263104 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0259386 |
| PTK2 | protein tyrosine kinase 2 | 0.0259089 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0257736 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0256429 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0255146 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0254947 |
| ZNF207 | zinc finger protein 207 | 0.0253372 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0248236 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0245899 |
| CLTC | clathrin, heavy chain (Hc) | 0.0245794 |
| RPS3 | ribosomal protein S3 | 0.0245708 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0245593 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.024241 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0238964 |
| RUNX1 | runt-related transcription factor 1 | 0.0238027 |
| S100A10 | S100 calcium binding protein A10 | 0.0237987 |
| CD2AP | CD2-associated protein | 0.0237922 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0236615 |
| PUM2 | pumilio RNA-binding family member 2 | 0.022656 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYO1E | myosin IE | -0.111727 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0753269 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.070943 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0675726 |
| ATOSA | atos homolog A | -0.0604189 |
| RAI14 | retinoic acid induced 14 | -0.0515659 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0512977 |
| NRG1 | neuregulin 1 | -0.0508181 |
| STK17A | serine/threonine kinase 17a | -0.0484919 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0478851 |
| S100A9 | S100 calcium binding protein A9 | -0.0467605 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0467086 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0461853 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0461357 |
| STC1 | stanniocalcin 1 | -0.045043 |
| LAMC2 | laminin, gamma 2 | -0.0448096 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0444346 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0434165 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.042677 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.042374 |
| RIGI | RNA sensor RIG-I | -0.0422115 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0420225 |
| EGFR | epidermal growth factor receptor | -0.0409506 |
| RAD51B | RAD51 paralog B | -0.0407027 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0394442 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0389051 |
| RBM25 | RNA binding motif protein 25 | -0.038591 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0382188 |
| FOXP1 | forkhead box P1 | -0.0380781 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0377181 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0373677 |
| LMO7 | LIM domain 7 | -0.0372912 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0372293 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0371865 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0371052 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0366648 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0365317 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0361011 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0357573 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0355803 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0347327 |
| COG5 | component of oligomeric golgi complex 5 | -0.0345334 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0342853 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0340782 |
| FAT1 | FAT atypical cadherin 1 | -0.0338265 |
| VCL | vinculin | -0.0336653 |
| MEF2A | myocyte enhancer factor 2A | -0.0335758 |
| DENND4A | DENN/MADD domain containing 4A | -0.0334262 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0331703 |
| ERBIN | erbb2 interacting protein | -0.0328829 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0327694 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0326726 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0326247 |
| SVIL | supervillin | -0.0323037 |
| SLMAP | sarcolemma associated protein | -0.0322529 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0321438 |
| GOLGB1 | golgin B1 | -0.0319217 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0318863 |
| DST | dystonin | -0.0316836 |
| POTEF | POTE ankyrin domain family, member F | -0.0316582 |
| SPAG9 | sperm associated antigen 9 | -0.0315775 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0312292 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0310216 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0307586 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.030296 |
| USP53 | ubiquitin specific peptidase 53 | -0.0302842 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0301164 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0299337 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0299186 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0298487 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0292808 |
| INHBA | inhibin, beta A | -0.0287909 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0287618 |
| MATR3 | matrin 3 | -0.0285824 |
| SMYD3 | SET and MYND domain containing 3 | -0.0285093 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0284537 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | -0.0283473 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0282415 |
| FRMD5 | FERM domain containing 5 | -0.0282143 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0277549 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0275854 |
| SEPTIN9 | septin 9 | -0.0275293 |
| FRMD4A | FERM domain containing 4A | -0.0273672 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0272014 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.026989 |
| RNF213 | ring finger protein 213 | -0.0269815 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0269756 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0267441 |
| SYT1 | synaptotagmin I | -0.0263861 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0263629 |
| MED13 | mediator complex subunit 13 | -0.0262062 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0261989 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0261045 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0260963 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0259767 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.025891 |
| LSAMP | limbic system-associated membrane protein | -0.0255383 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0255377 |
| VMP1 | vacuole membrane protein 1 | -0.0252251 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0249502 |
