| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Monocrotaline perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Monocrotaline_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.109971 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0716299 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.061952 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0522 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0490581 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0480529 |
| TXNRD1 | thioredoxin reductase 1 | 0.0412989 |
| OGA | O-GlcNAcase | 0.0389129 |
| RPS12 | ribosomal protein S12 | 0.0374181 |
| YBX1 | Y box binding protein 1 | 0.03605 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0359562 |
| PCBP2 | poly(rC) binding protein 2 | 0.0341828 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0336965 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.033114 |
| RTN4 | reticulon 4 | 0.0299708 |
| PHIP | pleckstrin homology domain interacting protein | 0.02957 |
| COPA | coatomer protein complex, subunit alpha | 0.0295058 |
| RPL37A | ribosomal protein L37a | 0.0292916 |
| XPO1 | exportin 1 | 0.0291259 |
| RPLP0 | ribosomal protein, large, P0 | 0.02827 |
| RPS3 | ribosomal protein S3 | 0.0282045 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0280814 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0279595 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0276532 |
| RPL37 | ribosomal protein L37 | 0.0266991 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.026624 |
| CEP192 | centrosomal protein 192kDa | 0.0261264 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.026103 |
| RPS8 | ribosomal protein S8 | 0.0253426 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0248451 |
| BBX | bobby sox homolog (Drosophila) | 0.0248241 |
| RRM2 | ribonucleotide reductase M2 | 0.024454 |
| RPL12 | ribosomal protein L12 | 0.0243576 |
| RPL23 | ribosomal protein L23 | 0.0240007 |
| GOLGA4 | golgin A4 | 0.0238757 |
| RBM25 | RNA binding motif protein 25 | 0.0227286 |
| PNN | pinin, desmosome associated protein | 0.0222341 |
| RPLP1 | ribosomal protein, large, P1 | 0.0222288 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0219918 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0217581 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0216412 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0216384 |
| LDHB | lactate dehydrogenase B | 0.0216065 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0215136 |
| TPX2 | TPX2, microtubule-associated | 0.0213045 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0210723 |
| RPL5 | ribosomal protein L5 | 0.0209879 |
| CENPF | centromere protein F, 350/400kDa | 0.0209316 |
| SET | SET nuclear proto-oncogene | 0.0208191 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0205448 |
| MORF4L2 | mortality factor 4 like 2 | 0.02018 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0198778 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0197977 |
| TPM3 | tropomyosin 3 | 0.0197867 |
| RPS4X | ribosomal protein S4, X-linked | 0.0196768 |
| SRP54 | signal recognition particle 54kDa | 0.0193607 |
| RPL26 | ribosomal protein L26 | 0.0190615 |
| DIAPH3 | diaphanous-related formin 3 | 0.0189978 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0188862 |
| RPS18 | ribosomal protein S18 | 0.0188814 |
| VIM | vimentin | 0.0187133 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0185769 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0185523 |
| ZNF292 | zinc finger protein 292 | 0.0182969 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0182538 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0182036 |
| SEPTIN7 | septin 7 | 0.0181415 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0180994 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0180395 |
| PREPL | prolyl endopeptidase-like | 0.0179022 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0178679 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0176692 |
| SPAG9 | sperm associated antigen 9 | 0.0176167 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0173196 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.016853 |
| RACK1 | receptor for activated C kinase 1 | 0.0167737 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.016717 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0166672 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0164727 |
| ANLN | anillin, actin binding protein | 0.0162126 |
| COG5 | component of oligomeric golgi complex 5 | 0.0162002 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0161518 |
| PGK1 | phosphoglycerate kinase 1 | 0.0160719 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0160467 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0159414 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0158431 |
| RLF | rearranged L-myc fusion | 0.0157954 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.015793 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0157608 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0157101 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0156349 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0154396 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0154133 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0153985 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0153263 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0152251 |
| GPSM2 | G-protein signaling modulator 2 | 0.0151011 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.015071 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0149982 |
| NDC80 | NDC80 kinetochore complex component | 0.0149146 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.46067 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.22281 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.142394 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.130726 |
| GRAMD1B | GRAM domain containing 1B | -0.124283 |
| OSMR | oncostatin M receptor | -0.120402 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0935208 |
| YBX3 | Y box binding protein 3 | -0.0916701 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0901956 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0769253 |
| PDE10A | phosphodiesterase 10A | -0.075495 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0710687 |
| HLA-B | major histocompatibility complex, class I, B | -0.0708038 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0707893 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0707481 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0698762 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0698224 |
| HMGA2 | high mobility group AT-hook 2 | -0.0669749 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0634263 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0597091 |
| ACTG1 | actin gamma 1 | -0.0587578 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0585082 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0571282 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.056677 |
| VCL | vinculin | -0.0560141 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0525095 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0517839 |
| TPM4 | tropomyosin 4 | -0.0515844 |
| AFF3 | AF4/FMR2 family, member 3 | -0.050366 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.049489 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.049485 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0490632 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0490596 |
| CDK17 | cyclin-dependent kinase 17 | -0.0486727 |
| STC1 | stanniocalcin 1 | -0.0486301 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0478379 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0475769 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0467023 |
| RYR3 | ryanodine receptor 3 | -0.0430939 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0430556 |
| MCL1 | myeloid cell leukemia 1 | -0.0427463 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0422609 |
| CUX1 | cut-like homeobox 1 | -0.0414051 |
| RNF213 | ring finger protein 213 | -0.039087 |
| EGR1 | early growth response 1 | -0.0388509 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0386051 |
| TMSB10 | thymosin beta 10 | -0.0384632 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0373176 |
| CDCP1 | CUB domain containing protein 1 | -0.0372959 |
| EGFR | epidermal growth factor receptor | -0.0372725 |
| FMNL2 | formin-like 2 | -0.0369787 |
| DENND5B | DENN/MADD domain containing 5B | -0.0362448 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0361703 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0361396 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0360195 |
| PYGL | phosphorylase, glycogen, liver | -0.0357709 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0355834 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0355397 |
| NF1 | neurofibromin 1 | -0.0351818 |
| CAVIN1 | caveolae associated protein 1 | -0.0348663 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0345062 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0343158 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0341613 |
| POTEF | POTE ankyrin domain family, member F | -0.0339874 |
| IER3 | immediate early response 3 | -0.0339225 |
| LOXL2 | lysyl oxidase-like 2 | -0.0338555 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.033758 |
| ATXN1 | ataxin 1 | -0.0333092 |
| EPAS1 | endothelial PAS domain protein 1 | -0.032022 |
| ATG7 | autophagy related 7 | -0.0314258 |
| LATS2 | large tumor suppressor kinase 2 | -0.031321 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0312361 |
| SVIL | supervillin | -0.031233 |
| ETV6 | ets variant 6 | -0.0311708 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0307857 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0301918 |
| SSH2 | slingshot protein phosphatase 2 | -0.0296683 |
| PTK2 | protein tyrosine kinase 2 | -0.0292812 |
| CCND1 | cyclin D1 | -0.029277 |
| BPTF | bromodomain PHD finger transcription factor | -0.028995 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0289187 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0289094 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0283158 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0282599 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0282275 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0279709 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.027669 |
| PHF14 | PHD finger protein 14 | -0.0270865 |
| IL6ST | interleukin 6 signal transducer | -0.02675 |
| MMP12 | matrix metallopeptidase 12 | -0.0266993 |
| BMP5 | bone morphogenetic protein 5 | -0.0266291 |
| KLF6 | Kruppel-like factor 6 | -0.0264158 |
| COL5A2 | collagen, type V, alpha 2 | -0.0254561 |
| IGF2 | insulin-like growth factor 2 | -0.025383 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0252437 |
| AHNAK | AHNAK nucleoprotein | -0.0251083 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0247381 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0243735 |
| VMP1 | vacuole membrane protein 1 | -0.0243298 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0236604 |
