| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Monocrotaline perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Monocrotaline_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.162796 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.14296 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.116777 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.112544 |
| ASPH | aspartate beta-hydroxylase | 0.111657 |
| NDRG1 | N-myc downstream regulated 1 | 0.106903 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.102787 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.102376 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0836571 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.080476 |
| TPM3 | tropomyosin 3 | 0.0755351 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0663139 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0655977 |
| UBC | ubiquitin C | 0.0608504 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0601502 |
| DSPP | dentin sialophosphoprotein | 0.0600199 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0589054 |
| PTK2 | protein tyrosine kinase 2 | 0.0586562 |
| LAMC2 | laminin, gamma 2 | 0.0540336 |
| MSN | moesin | 0.0528894 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0524684 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0521738 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0515064 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0511631 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0507139 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0497397 |
| TMSB4X | thymosin beta 4, X-linked | 0.0484167 |
| TXNRD1 | thioredoxin reductase 1 | 0.0475397 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0473539 |
| ENO1 | enolase 1, (alpha) | 0.0465871 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0461824 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0460768 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0459775 |
| SQSTM1 | sequestosome 1 | 0.0459094 |
| LDHA | lactate dehydrogenase A | 0.0458671 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0456451 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0450912 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0450491 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0446918 |
| TFG | TRK-fused gene | 0.0446304 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0441622 |
| HMGB2 | high mobility group box 2 | 0.0422799 |
| PAPOLA | poly(A) polymerase alpha | 0.0420671 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0410933 |
| PGK1 | phosphoglycerate kinase 1 | 0.0409423 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0408812 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0402012 |
| NAV2 | neuron navigator 2 | 0.039955 |
| FAM13A | family with sequence similarity 13, member A | 0.0399214 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0377386 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0374027 |
| ZNF292 | zinc finger protein 292 | 0.036487 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0358902 |
| RPS2 | ribosomal protein S2 | 0.0356994 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0350185 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0342233 |
| NCKAP1 | NCK-associated protein 1 | 0.0342015 |
| CCNL1 | cyclin L1 | 0.0340228 |
| FHIT | fragile histidine triad | 0.0337712 |
| ANLN | anillin, actin binding protein | 0.0334728 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0332933 |
| CLINT1 | clathrin interactor 1 | 0.0332719 |
| RYBP | RING1 and YY1 binding protein | 0.0331882 |
| ARRDC3 | arrestin domain containing 3 | 0.033162 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0328333 |
| PCBP2 | poly(rC) binding protein 2 | 0.0326807 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0326777 |
| MYO6 | myosin VI | 0.0325634 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0322495 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0321973 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0319496 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0317965 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0316753 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0315071 |
| AHNAK | AHNAK nucleoprotein | 0.0313957 |
| MKI67 | marker of proliferation Ki-67 | 0.0312782 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0310808 |
| DSTN | destrin (actin depolymerizing factor) | 0.0310633 |
| SET | SET nuclear proto-oncogene | 0.0307391 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0301699 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 0.0300529 |
| TMF1 | TATA element modulatory factor 1 | 0.0300218 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0296864 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0296273 |
| RPL3 | ribosomal protein L3 | 0.0295952 |
| CENPF | centromere protein F, 350/400kDa | 0.029359 |
| RPS18 | ribosomal protein S18 | 0.0293418 |
| NUP58 | nucleoporin 58 | 0.029316 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0289422 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0289243 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0284367 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0281897 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0281261 |
| GOLGA4 | golgin A4 | 0.02753 |
| SPAG9 | sperm associated antigen 9 | 0.0271824 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0271189 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0271147 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0267239 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0267188 |
| MATR3 | matrin 3 | 0.0265773 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.260752 |
| TMSB10 | thymosin beta 10 | -0.136116 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.101679 |
| ACTG1 | actin gamma 1 | -0.0892266 |
| RPL35A | ribosomal protein L35a | -0.0775676 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0774481 |
| PTMA | prothymosin, alpha | -0.0601886 |
| RPLP1 | ribosomal protein, large, P1 | -0.0467973 |
| RPL34 | ribosomal protein L34 | -0.0438731 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.043144 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0420742 |
| CSTB | cystatin B (stefin B) | -0.0411373 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0405709 |
| RPS19 | ribosomal protein S19 | -0.0401776 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.038117 |
| RPLP2 | ribosomal protein, large, P2 | -0.0375285 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0372852 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0364548 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0362122 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0350413 |
| MT2A | metallothionein 2A | -0.033265 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0301061 |
| HLA-A | major histocompatibility complex, class I, A | -0.0295045 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0290273 |
| HMGA1 | high mobility group AT-hook 1 | -0.028513 |
| LMO7 | LIM domain 7 | -0.0284945 |
| VIM | vimentin | -0.0282541 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0279829 |
| GNAS | GNAS complex locus | -0.0278018 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0275367 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0251179 |
| S100A9 | S100 calcium binding protein A9 | -0.0247681 |
| EXT1 | exostosin glycosyltransferase 1 | -0.02424 |
| TMEM165 | transmembrane protein 165 | -0.0240518 |
| RPS29 | ribosomal protein S29 | -0.023987 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0239808 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0237728 |
| RASAL2 | RAS protein activator like 2 | -0.023709 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0231342 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0230242 |
| RPL36 | ribosomal protein L36 | -0.022441 |
| EGR1 | early growth response 1 | -0.0220994 |
| TPI1 | triosephosphate isomerase 1 | -0.0219998 |
| MYO1E | myosin IE | -0.0217049 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0213894 |
| S100A10 | S100 calcium binding protein A10 | -0.0213124 |
| RPS13 | ribosomal protein S13 | -0.0204545 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.020409 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0200467 |
| RPL23 | ribosomal protein L23 | -0.0198865 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0195102 |
| RPL31 | ribosomal protein L31 | -0.0193312 |
| RPS27 | ribosomal protein S27 | -0.0191222 |
| RPL36AL | ribosomal protein L36a-like | -0.018967 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0189444 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.0186835 |
| S100A6 | S100 calcium binding protein A6 | -0.0186335 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0184519 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0179674 |
| OCLN | occludin | -0.0179155 |
| ARF1 | ADP-ribosylation factor 1 | -0.0174123 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0173114 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0165955 |
| EFNA5 | ephrin-A5 | -0.016516 |
| EGFR | epidermal growth factor receptor | -0.0164488 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0163888 |
| CDK13 | cyclin-dependent kinase 13 | -0.0160972 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0160939 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.016066 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0160589 |
| RNF213 | ring finger protein 213 | -0.0158796 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0158578 |
| RPS14 | ribosomal protein S14 | -0.0158575 |
| RPS3 | ribosomal protein S3 | -0.0158035 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0158003 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.015731 |
| FBXO11 | F-box protein 11 | -0.0156293 |
| TBCA | tubulin folding cofactor A | -0.0154557 |
| RRBP1 | ribosome binding protein 1 | -0.0154534 |
| HLA-B | major histocompatibility complex, class I, B | -0.0154384 |
| RPS8 | ribosomal protein S8 | -0.0153824 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0151042 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0148741 |
| RPS16 | ribosomal protein S16 | -0.0148659 |
| CLDN4 | claudin 4 | -0.0144996 |
| NRP1 | neuropilin 1 | -0.0144962 |
| HLA-E | major histocompatibility complex, class I, E | -0.0142009 |
| OSMR | oncostatin M receptor | -0.0141854 |
| MX2 | MX dynamin-like GTPase 2 | -0.0138825 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0137765 |
| MCU | mitochondrial calcium uniporter | -0.0137068 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0136682 |
| TMEM263 | transmembrane protein 263 | -0.013648 |
| PALLD | palladin, cytoskeletal associated protein | -0.0135995 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0133366 |
| RPL8 | ribosomal protein L8 | -0.0132953 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0131835 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0130343 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0129796 |
| UBAP1 | ubiquitin associated protein 1 | -0.012968 |
