| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Monocrotaline perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Monocrotaline_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.151936 |
| COL5A2 | collagen, type V, alpha 2 | 0.10581 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0804921 |
| SPAG9 | sperm associated antigen 9 | 0.0792915 |
| DST | dystonin | 0.0779629 |
| ZNF292 | zinc finger protein 292 | 0.0731305 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0686462 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0586426 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0572778 |
| TMSB4X | thymosin beta 4, X-linked | 0.0543828 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0518624 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0509981 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0509296 |
| PCDH9 | protocadherin 9 | 0.0492622 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0490627 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0474654 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0464502 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0459283 |
| LIN28B | lin-28 homolog B (C. elegans) | 0.0452504 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0443819 |
| TPM3 | tropomyosin 3 | 0.0433568 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0399167 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0379134 |
| THBS1 | thrombospondin 1 | 0.0378192 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0361512 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0361405 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0360174 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0359509 |
| APP | amyloid beta (A4) precursor protein | 0.0359225 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0357237 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0344429 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0341929 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0341205 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0338015 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.033705 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0334234 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.033394 |
| PGK1 | phosphoglycerate kinase 1 | 0.0329892 |
| ZFR | zinc finger RNA binding protein | 0.0327931 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0323135 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0322712 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0315208 |
| RTN4 | reticulon 4 | 0.0314096 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0304139 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0302789 |
| RHEB | Ras homolog enriched in brain | 0.0301132 |
| AHNAK | AHNAK nucleoprotein | 0.0300607 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0298059 |
| CAVIN1 | caveolae associated protein 1 | 0.0293999 |
| H1-4 | H1.4 linker histone, cluster member | 0.0293481 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.0292795 |
| CD2AP | CD2-associated protein | 0.0289012 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0288737 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0285831 |
| DKC1 | dyskeratosis congenita 1, dyskerin | 0.0285068 |
| YBX1 | Y box binding protein 1 | 0.0283868 |
| PEG10 | paternally expressed 10 | 0.028338 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0280662 |
| COL3A1 | collagen, type III, alpha 1 | 0.0278182 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0277995 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0274199 |
| PLS3 | plastin 3 | 0.0273035 |
| MORF4L1 | mortality factor 4 like 1 | 0.0268274 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0265969 |
| GPC3 | glypican 3 | 0.0263513 |
| NCKAP1 | NCK-associated protein 1 | 0.0261754 |
| ANXA2 | annexin A2 | 0.0261531 |
| SLC30A8 | solute carrier family 30 (zinc transporter), member 8 | 0.0258015 |
| RYBP | RING1 and YY1 binding protein | 0.0257994 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0256996 |
| RAB14 | RAB14, member RAS oncogene family | 0.0255657 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0253601 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0252842 |
| ANXA5 | annexin A5 | 0.0252741 |
| RHOH | ras homolog family member H | 0.0250633 |
| RBBP7 | retinoblastoma binding protein 7 | 0.025063 |
| OLA1 | Obg-like ATPase 1 | 0.0249818 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0249035 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0248758 |
| ANKRD33B | ankyrin repeat domain 33B | 0.024813 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0247839 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.024592 |
| TPM1 | tropomyosin 1 (alpha) | 0.024498 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0243037 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0240733 |
| ZNF608 | zinc finger protein 608 | 0.0240434 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0240162 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0239099 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.0238047 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0238007 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0237855 |
| FNBP1L | formin binding protein 1-like | 0.023714 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0236062 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0235866 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0235058 |
| POU2F1 | POU class 2 homeobox 1 | 0.0233187 |
| CRY1 | cryptochrome circadian clock 1 | 0.0232339 |
| ARF1 | ADP-ribosylation factor 1 | 0.0232201 |
| RAB31 | RAB31, member RAS oncogene family | 0.023093 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0230561 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.104768 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0854728 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0780964 |
| TMSB10 | thymosin beta 10 | -0.0667127 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0659419 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0638795 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0580659 |
| LRRC4C | leucine rich repeat containing 4C | -0.0566237 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0522718 |
| PRKD1 | protein kinase D1 | -0.0499641 |
| SRP54 | signal recognition particle 54kDa | -0.0490804 |
| PHIP | pleckstrin homology domain interacting protein | -0.0486515 |
| MED13L | mediator complex subunit 13-like | -0.0477914 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0477134 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0467743 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0460021 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0439347 |
| LPIN2 | lipin 2 | -0.0433539 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0423164 |
| HDAC9 | histone deacetylase 9 | -0.0411771 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0410025 |
| PFN1 | profilin 1 | -0.0409399 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0380494 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0378743 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0378701 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0375246 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0373932 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | -0.0370932 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0367616 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0357346 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.033425 |
| NEBL | nebulette | -0.0333425 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0325776 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0324998 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0324072 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0319307 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0315165 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0313712 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0310819 |
| PRTG | protogenin | -0.0305748 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0303617 |
| RPS8 | ribosomal protein S8 | -0.0302855 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0300264 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0297217 |
| FNDC3B | fibronectin type III domain containing 3B | -0.029589 |
| URI1 | URI1, prefoldin-like chaperone | -0.0291775 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0288723 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0282806 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.028245 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha | -0.0280006 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0276689 |
| CUX1 | cut-like homeobox 1 | -0.0274947 |
| RNF13 | ring finger protein 13 | -0.0269058 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0267163 |
| PRR16 | proline rich 16 | -0.0265844 |
| POTEF | POTE ankyrin domain family, member F | -0.0263782 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0261412 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | -0.0261327 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0260349 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0259218 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | -0.0257706 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -0.0257025 |
| TRERF1 | transcriptional regulating factor 1 | -0.0256562 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0256448 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0255874 |
| LATS2 | large tumor suppressor kinase 2 | -0.0249739 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0248738 |
| PGPEP1L | pyroglutamyl-peptidase I-like | -0.0246876 |
| COL1A2 | collagen, type I, alpha 2 | -0.0246574 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0245663 |
| SNX14 | sorting nexin 14 | -0.0245403 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0245204 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0241954 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0241567 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0241461 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -0.0241233 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0241182 |
| PCBP2 | poly(rC) binding protein 2 | -0.0237131 |
| GPATCH8 | G patch domain containing 8 | -0.0237049 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0235835 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0235206 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0234602 |
| NHSL1 | NHS-like 1 | -0.0230951 |
| NXN | nucleoredoxin | -0.023078 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0230655 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0229319 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0229316 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0227312 |
| ATP9A | ATPase, class II, type 9A | -0.022723 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0226702 |
| CDH19 | cadherin 19, type 2 | -0.0225729 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0223082 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0222681 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0222127 |
| RPL28 | ribosomal protein L28 | -0.022165 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0221124 |
| PCDH17 | protocadherin 17 | -0.022101 |
| ATXN2 | ataxin 2 | -0.0220906 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.022077 |
| MYADM | myeloid-associated differentiation marker | -0.0220128 |
