| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Monocrotaline perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Monocrotaline_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.297869 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0901596 |
| FAM13A | family with sequence similarity 13, member A | 0.0838854 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0792051 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0776461 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0703125 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0683821 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0634665 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0552904 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0457418 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.045014 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0443266 |
| SDC4 | syndecan 4 | 0.0429621 |
| NRXN3 | neurexin 3 | 0.0429592 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0429558 |
| ATP13A3 | ATPase type 13A3 | 0.0427496 |
| ZNF395 | zinc finger protein 395 | 0.0413318 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0394835 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0387554 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0369533 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0368573 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0363376 |
| MYOF | myoferlin | 0.0357207 |
| IL6 | interleukin 6 | 0.0356828 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0345127 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0343639 |
| SPAG9 | sperm associated antigen 9 | 0.0342405 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0337198 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0333865 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0333652 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0332063 |
| MAP1B | microtubule-associated protein 1B | 0.0329038 |
| RTN4 | reticulon 4 | 0.0326953 |
| ARRDC3 | arrestin domain containing 3 | 0.0326697 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0326692 |
| MSN | moesin | 0.0325018 |
| NUP58 | nucleoporin 58 | 0.0323409 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.032333 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0321098 |
| PCBP2 | poly(rC) binding protein 2 | 0.0312148 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0302273 |
| HIP1 | huntingtin interacting protein 1 | 0.0302077 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0294675 |
| SFXN1 | sideroflexin 1 | 0.0292441 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0291904 |
| COPA | coatomer protein complex, subunit alpha | 0.0290638 |
| AHNAK | AHNAK nucleoprotein | 0.0289195 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0287632 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0286625 |
| ZNF292 | zinc finger protein 292 | 0.0282057 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0281979 |
| CCNL1 | cyclin L1 | 0.0279775 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0278188 |
| CCDC14 | coiled-coil domain containing 14 | 0.0274576 |
| NBAS | neuroblastoma amplified sequence | 0.0273713 |
| SMAD3 | SMAD family member 3 | 0.0269848 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0269528 |
| TMEM123 | transmembrane protein 123 | 0.026939 |
| PRELID2 | PRELI domain containing 2 | 0.0268987 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0268088 |
| MYO10 | myosin X | 0.0267633 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0263015 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0262606 |
| LOXL2 | lysyl oxidase-like 2 | 0.0261651 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0260639 |
| RLF | rearranged L-myc fusion | 0.0260545 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0259902 |
| ANXA2 | annexin A2 | 0.0255529 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0253583 |
| USP3 | ubiquitin specific peptidase 3 | 0.0252935 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0252604 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.025045 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0249871 |
| ZFR | zinc finger RNA binding protein | 0.0249745 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0249217 |
| RNF24 | ring finger protein 24 | 0.0248997 |
| APP | amyloid beta (A4) precursor protein | 0.0248732 |
| NPTN | neuroplastin | 0.0248577 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0246862 |
| METTL15 | methyltransferase like 15 | 0.0240436 |
| CDC73 | cell division cycle 73 | 0.0239437 |
| CD109 | CD109 molecule | 0.0238607 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.023855 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0238514 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0238067 |
| TMSB4X | thymosin beta 4, X-linked | 0.0236605 |
| RBM25 | RNA binding motif protein 25 | 0.0236143 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0236138 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0235237 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0233751 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0230608 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0229173 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.022893 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0226273 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0225805 |
| COL5A2 | collagen, type V, alpha 2 | 0.022398 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0223669 |
| FAT1 | FAT atypical cadherin 1 | 0.0223242 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0222313 |
| FNIP1 | folliculin interacting protein 1 | 0.0222073 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.199928 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.159222 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.112098 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110591 |
| HLA-B | major histocompatibility complex, class I, B | -0.0872283 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.086554 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0650847 |
| PTMA | prothymosin, alpha | -0.0624587 |
| FTL | ferritin, light polypeptide | -0.0616865 |
| TMSB10 | thymosin beta 10 | -0.059645 |
| VIM | vimentin | -0.0566108 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0557184 |
| HLA-C | major histocompatibility complex, class I, C | -0.0547069 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0469661 |
| COL1A1 | collagen, type I, alpha 1 | -0.0435111 |
| EGFR | epidermal growth factor receptor | -0.0413692 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0407117 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0399253 |
| B2M | beta-2-microglobulin | -0.0398485 |
| RPS23 | ribosomal protein S23 | -0.0396951 |
| TPM4 | tropomyosin 4 | -0.0394159 |
| RPL34 | ribosomal protein L34 | -0.0393472 |
| MT2A | metallothionein 2A | -0.0372329 |
| RPL35A | ribosomal protein L35a | -0.0361784 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0349172 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0346637 |
| POTEF | POTE ankyrin domain family, member F | -0.0346379 |
| RPS8 | ribosomal protein S8 | -0.0340401 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0330916 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.032717 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.031816 |
| HM13 | histocompatibility (minor) 13 | -0.0313404 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0303791 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0302742 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.029818 |
| RPS29 | ribosomal protein S29 | -0.0297153 |
| RRBP1 | ribosome binding protein 1 | -0.0295829 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0291707 |
| RPL37 | ribosomal protein L37 | -0.0281187 |
| GOLGB1 | golgin B1 | -0.027897 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0272839 |
| RPL31 | ribosomal protein L31 | -0.0270359 |
| FLOT1 | flotillin 1 | -0.0269495 |
| RPLP2 | ribosomal protein, large, P2 | -0.0269369 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0263873 |
| HMGA2 | high mobility group AT-hook 2 | -0.0261778 |
| GLIS3 | GLIS family zinc finger 3 | -0.0260896 |
| ENO1 | enolase 1, (alpha) | -0.0260277 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0260179 |
| RPL15 | ribosomal protein L15 | -0.02591 |
| DSTN | destrin (actin depolymerizing factor) | -0.025805 |
| LMNA | lamin A/C | -0.0257572 |
| ADM | adrenomedullin | -0.0251019 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0247791 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0246921 |
| TRIM56 | tripartite motif containing 56 | -0.0244199 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0243812 |
| TBCA | tubulin folding cofactor A | -0.0238059 |
| FN1 | fibronectin 1 | -0.0237751 |
| SELENOK | selenoprotein K | -0.0237084 |
| FBXO11 | F-box protein 11 | -0.0236093 |
| STC2 | stanniocalcin 2 | -0.0234751 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0229827 |
| RPL23 | ribosomal protein L23 | -0.0229763 |
| RPS25 | ribosomal protein S25 | -0.0226699 |
| RPS13 | ribosomal protein S13 | -0.0226017 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0224369 |
| LMAN2 | lectin, mannose-binding 2 | -0.0221201 |
| ATG7 | autophagy related 7 | -0.021775 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0216086 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0214167 |
| OAZ1 | ornithine decarboxylase antizyme 1 | -0.0212897 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0209784 |
| RPL28 | ribosomal protein L28 | -0.0208255 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0208171 |
| CANX | calnexin | -0.0206235 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0206181 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0205517 |
| OST4 | oligosaccharyltransferase 4 homolog (S. cerevisiae) | -0.0204212 |
| SIL1 | SIL1 nucleotide exchange factor | -0.0203656 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0203536 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.020274 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0202167 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0201295 |
| NUP98 | nucleoporin 98kDa | -0.0201005 |
| RPS14 | ribosomal protein S14 | -0.0200369 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0197477 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0197328 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0197242 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0197067 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 | -0.0195577 |
| VCP | valosin containing protein | -0.0195288 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0193597 |
| YIPF5 | Yip1 domain family, member 5 | -0.0192442 |
| NOP56 | NOP56 ribonucleoprotein | -0.0192323 |
| KMT5B | lysine methyltransferase 5B | -0.0192187 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0191079 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0191041 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0190713 |
| DTNA | dystrobrevin, alpha | -0.0188749 |
