Monocytosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An increased number of circulating monocytes. (Human Phenotype Ontology, HP_0012311)
External Link https://www.disgenet.org/browser/0/1/0/C0085702
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Genes

60 genes associated with the disease Monocytosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
APOA1 apolipoprotein A-I
BCL2 B-cell CLL/lymphoma 2
BCR breakpoint cluster region
CCL8 chemokine (C-C motif) ligand 8
CCR2 chemokine (C-C motif) receptor 2
CD14 CD14 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CNTNAP1 contactin associated protein 1
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DYM dymeclin
EGR1 early growth response 1
ELANE elastase, neutrophil expressed
ETV6 ets variant 6
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FLT3 fms-related tyrosine kinase 3
G6PC3 glucose 6 phosphatase, catalytic, 3
GFI1 growth factor independent 1 transcription repressor
HCRT hypocretin (orexin) neuropeptide precursor
IL10 interleukin 10
IL17A interleukin 17A
IL23A interleukin 23, alpha subunit p19
IL3 interleukin 3
IL6 interleukin 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
JAK2 Janus kinase 2
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
MLXIPL MLX interacting protein-like
MOK MOK protein kinase
MTTP microsomal triglyceride transfer protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
OSCP1 organic solute carrier partner 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RUNX1 runt-related transcription factor 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SRP54 signal recognition particle 54kDa
SRSF2 serine/arginine-rich splicing factor 2
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TEK TEK tyrosine kinase, endothelial
TET2 tet methylcytosine dioxygenase 2
TNF tumor necrosis factor
TP53 tumor protein p53
TREM1 triggering receptor expressed on myeloid cells 1