Morphine Dependence Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An opiate dependence that involves the continued use of morphine despite despite problems related to use of the substance. (Human Disease Ontology, DOID_2560)
External Link https://www.disgenet.org/browser/0/1/0/C0026552
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Genes

41 genes associated with the disease Morphine Dependence in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
AQP4 aquaporin 4
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
CARTPT CART prepropeptide
CCK cholecystokinin
CCKBR cholecystokinin B receptor
CCL28 chemokine (C-C motif) ligand 28
CLOCK clock circadian regulator
CREB1 cAMP responsive element binding protein 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DRD2 dopamine receptor D2
FADD Fas (TNFRSF6)-associated via death domain
FGFR3 fibroblast growth factor receptor 3
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
HCRT hypocretin (orexin) neuropeptide precursor
HCRTR1 hypocretin (orexin) receptor 1
MDH2 malate dehydrogenase 2, NAD (mitochondrial)
MMP9 matrix metallopeptidase 9
NOS1 nitric oxide synthase 1 (neuronal)
NPS neuropeptide S
NPSR1 neuropeptide S receptor 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
OPRL1 opiate receptor-like 1
OPRM1 opioid receptor, mu 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PITX3 paired-like homeodomain 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
TH tyrosine hydroxylase
TLR4 toll-like receptor 4
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TXN thioredoxin
ZCRB1 zinc finger CCHC-type and RNA binding motif 1