| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/4810 |
| Similar Terms | |
| Downloads & Tools |
198 proteins with high or low expression in Moxonidine relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ARHGAP44 | Rho GTPase activating protein 44 | 2.1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 1.12 |
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 | 1.04 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | 0.95 |
| ENDOV | endonuclease V | 0.67 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.63 |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase | 0.62 |
| RHOC | ras homolog family member C | 0.55 |
| CLSPN | claspin | 0.52 |
| ZNF664 | zinc finger protein 664 | 0.5 |
| ZNF317 | zinc finger protein 317 | 0.5 |
| NRP1 | neuropilin 1 | 0.49 |
| ZNF768 | zinc finger protein 768 | 0.48 |
| MAGEF1 | melanoma antigen family F1 | 0.48 |
| DMD | dystrophin | 0.47 |
| BTBD7 | BTB (POZ) domain containing 7 | 0.47 |
| TBC1D31 | TBC1 domain family, member 31 | 0.45 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) | 0.44 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.44 |
| ASB8 | ankyrin repeat and SOCS box containing 8 | 0.43 |
| AKIRIN2 | akirin 2 | 0.43 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) | 0.42 |
| TFR2 | transferrin receptor 2 | 0.42 |
| ZIC2 | Zic family member 2 | 0.42 |
| PLEKHG4 | pleckstrin homology domain containing, family G (with RhoGef domain) member 4 | 0.41 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 0.41 |
| ZNF451 | zinc finger protein 451 | 0.4 |
| MIIP | migration and invasion inhibitory protein | 0.39 |
| ZNF337 | zinc finger protein 337 | 0.38 |
| BOK | BCL2-related ovarian killer | 0.38 |
| MYO15B | myosin XVB | 0.38 |
| ZNRD1 | zinc ribbon domain containing 1 | 0.38 |
| OTX1 | orthodenticle homeobox 1 | 0.37 |
| SPOPL | speckle-type POZ protein-like | 0.36 |
| TMEM222 | transmembrane protein 222 | 0.36 |
| UNC80 | unc-80 homolog (C. elegans) | 0.35 |
| SPTA1 | spectrin, alpha, erythrocytic 1 | 0.35 |
| MFSD14B | major facilitator superfamily domain containing 14B | 0.35 |
| RPS27A | ribosomal protein S27a | 0.35 |
| CEP68 | centrosomal protein 68kDa | 0.34 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.33 |
| CDK14 | cyclin-dependent kinase 14 | 0.33 |
| RPL6 | ribosomal protein L6 | 0.33 |
| KPTN | kaptin (actin binding protein) | 0.33 |
| RPL31 | ribosomal protein L31 | 0.33 |
| TP73 | tumor protein p73 | 0.33 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 | 0.33 |
| R3HDM4 | R3H domain containing 4 | 0.33 |
| CORO2A | coronin, actin binding protein, 2A | 0.32 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.31 |
| MCM10 | minichromosome maintenance complex component 10 | 0.31 |
| RNF17 | ring finger protein 17 | 0.31 |
| CCDC18 | coiled-coil domain containing 18 | 0.31 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.31 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 | 0.3 |
| GPN3 | GPN-loop GTPase 3 | 0.3 |
| TMEM14C | transmembrane protein 14C | 0.3 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.3 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 | 0.3 |
| TPGS1 | tubulin polyglutamylase complex subunit 1 | 0.29 |
| GSKIP | GSK3B interacting protein | 0.29 |
| RNF138 | ring finger protein 138, E3 ubiquitin protein ligase | 0.29 |
| DCLRE1C | DNA cross-link repair 1C | 0.29 |
| RNF111 | ring finger protein 111 | 0.28 |
| USP33 | ubiquitin specific peptidase 33 | 0.28 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 0.28 |
| TADA2A | transcriptional adaptor 2A | 0.28 |
| HCFC2 | host cell factor C2 | 0.28 |
| PTS | 6-pyruvoyltetrahydropterin synthase | 0.28 |
| PTTG1 | pituitary tumor-transforming 1 | 0.27 |
| ABHD17C | abhydrolase domain containing 17C | 0.27 |
| AUNIP | aurora kinase A and ninein interacting protein | 0.27 |
| UBN2 | ubinuclein 2 | 0.27 |
| GPANK1 | G patch domain and ankyrin repeats 1 | 0.27 |
| ZNF503 | zinc finger protein 503 | 0.27 |
| STK33 | serine/threonine kinase 33 | 0.27 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.27 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.27 |
| TOMM5 | translocase of outer mitochondrial membrane 5 homolog (yeast) | 0.27 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.27 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.26 |
| HDAC7 | histone deacetylase 7 | 0.26 |
| ENTPD2 | ectonucleoside triphosphate diphosphohydrolase 2 | 0.26 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 | 0.26 |
| LIPE | lipase, hormone-sensitive | 0.26 |
| FBXL3 | F-box and leucine-rich repeat protein 3 | 0.26 |
| PISD | phosphatidylserine decarboxylase | 0.26 |
| AMMECR1L | AMMECR1-like | 0.26 |
| PITX1 | paired-like homeodomain 1 | 0.26 |
| PRKCQ | protein kinase C, theta | 0.25 |
| C1D | C1D nuclear receptor corepressor | 0.25 |
| LIPT1 | lipoyltransferase 1 | 0.25 |
| FAM3A | family with sequence similarity 3, member A | 0.25 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.25 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.25 |
| IQCB1 | IQ motif containing B1 | 0.25 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.25 |
| FZD2 | frizzled class receptor 2 | 0.25 |
| CCNQ | cyclin Q | 0.25 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -1.38 |
| LYRM1 | LYR motif containing 1 | -0.9 |
| HMCN1 | hemicentin 1 | -0.74 |
| USP19 | ubiquitin specific peptidase 19 | -0.71 |
| CLSTN3 | calsyntenin 3 | -0.66 |
| ECM1 | extracellular matrix protein 1 | -0.66 |
| ENO1 | enolase 1, (alpha) | -0.66 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | -0.58 |
| PLCB4 | phospholipase C, beta 4 | -0.56 |
| GPATCH2L | G patch domain containing 2-like | -0.56 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) | -0.52 |
| MDP1 | magnesium-dependent phosphatase 1 | -0.52 |
| GLRX | glutaredoxin (thioltransferase) | -0.49 |
| IGSF8 | immunoglobulin superfamily, member 8 | -0.48 |
| ATP13A2 | ATPase type 13A2 | -0.48 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.48 |
| MXRA7 | matrix-remodelling associated 7 | -0.48 |
| IRF2 | interferon regulatory factor 2 | -0.47 |
| CBR3 | carbonyl reductase 3 | -0.46 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | -0.46 |
| CCN3 | cellular communication network factor 3 | -0.46 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | -0.45 |
| SERAC1 | serine active site containing 1 | -0.45 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.42 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) | -0.41 |
| TPM4 | tropomyosin 4 | -0.4 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | -0.4 |
| S100A2 | S100 calcium binding protein A2 | -0.4 |
| DTNA | dystrobrevin, alpha | -0.4 |
| LYST | lysosomal trafficking regulator | -0.4 |
| ANTXR2 | anthrax toxin receptor 2 | -0.4 |
| C1ORF50 | chromosome 1 open reading frame 50 | -0.39 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 | -0.39 |
| BAG4 | BCL2-associated athanogene 4 | -0.39 |
| TNNC2 | troponin C type 2 (fast) | -0.39 |
| JUN | jun proto-oncogene | -0.38 |
| NGFR | nerve growth factor receptor | -0.38 |
| ZNF700 | zinc finger protein 700 | -0.37 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -0.37 |
| NRBF2 | nuclear receptor binding factor 2 | -0.37 |
| DNM1 | dynamin 1 | -0.37 |
| BCOR | BCL6 corepressor | -0.36 |
| TECPR1 | tectonin beta-propeller repeat containing 1 | -0.36 |
| SGMS2 | sphingomyelin synthase 2 | -0.36 |
| LDHD | lactate dehydrogenase D | -0.36 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing | -0.36 |
| ZSCAN21 | zinc finger and SCAN domain containing 21 | -0.35 |
| CLIC3 | chloride intracellular channel 3 | -0.35 |
| SNX33 | sorting nexin 33 | -0.35 |
| CMC1 | C-x(9)-C motif containing 1 | -0.34 |
| TRAM2 | translocation associated membrane protein 2 | -0.34 |
| KDF1 | keratinocyte differentiation factor 1 | -0.34 |
| ZNF749 | zinc finger protein 749 | -0.33 |
| TSPAN9 | tetraspanin 9 | -0.33 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.33 |
| MSX1 | msh homeobox 1 | -0.33 |
| REPS2 | RALBP1 associated Eps domain containing 2 | -0.33 |
| RNF135 | ring finger protein 135 | -0.33 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.33 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.33 |
| ASB7 | ankyrin repeat and SOCS box containing 7 | -0.32 |
| SNX21 | sorting nexin family member 21 | -0.32 |
| PML | promyelocytic leukemia | -0.32 |
| RCE1 | Ras converting CAAX endopeptidase 1 | -0.31 |
| SERINC1 | serine incorporator 1 | -0.31 |
| MYO18B | myosin XVIIIB | -0.31 |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 | -0.31 |
| TEP1 | telomerase-associated protein 1 | -0.31 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.31 |
| TSPAN15 | tetraspanin 15 | -0.31 |
| GON7 | GON7 subunit of KEOPS complex | -0.31 |
| RABAC1 | Rab acceptor 1 (prenylated) | -0.31 |
| KLHL15 | kelch-like family member 15 | -0.3 |
| SRXN1 | sulfiredoxin 1 | -0.3 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.3 |
| ZZZ3 | zinc finger, ZZ-type containing 3 | -0.3 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.3 |
| STK16 | serine/threonine kinase 16 | -0.3 |
| DNAH9 | dynein, axonemal, heavy chain 9 | -0.3 |
| BAIAP3 | BAI1-associated protein 3 | -0.3 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.3 |
| TMEM129 | transmembrane protein 129, E3 ubiquitin protein ligase | -0.3 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | -0.3 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.29 |
| CES2 | carboxylesterase 2 | -0.29 |
| LAMTOR4 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 | -0.29 |
| TADA2B | transcriptional adaptor 2B | -0.29 |
| TMEM94 | transmembrane protein 94 | -0.29 |
| ENPP5 | ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) | -0.29 |
| SLC22A18 | solute carrier family 22, member 18 | -0.29 |
| OTUD5 | OTU deubiquitinase 5 | -0.28 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | -0.28 |
| KCTD21 | potassium channel tetramerization domain containing 21 | -0.28 |
| PGPEP1 | pyroglutamyl-peptidase I | -0.28 |
| ZNF771 | zinc finger protein 771 | -0.28 |
| EMB | embigin | -0.28 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.28 |
| C18ORF32 | chromosome 18 open reading frame 32 | -0.28 |
| ZNF865 | zinc finger protein 865 | -0.28 |
