| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.239146 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.228018 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.210896 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.118597 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.116114 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.112149 |
| PODXL | podocalyxin-like | 0.103746 |
| CANX | calnexin | 0.0956054 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0935794 |
| DST | dystonin | 0.0843212 |
| CALR | calreticulin | 0.0840828 |
| APP | amyloid beta (A4) precursor protein | 0.0835183 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.081682 |
| COL3A1 | collagen, type III, alpha 1 | 0.0816731 |
| LOXL2 | lysyl oxidase-like 2 | 0.0794979 |
| FBN1 | fibrillin 1 | 0.0757384 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0757007 |
| MYOF | myoferlin | 0.0752522 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0746745 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0743071 |
| AUTS2 | autism susceptibility candidate 2 | 0.0729839 |
| ATP13A3 | ATPase type 13A3 | 0.0706373 |
| THBS2 | thrombospondin 2 | 0.0703387 |
| SEPTIN9 | septin 9 | 0.0687286 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.065819 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.065021 |
| NAV2 | neuron navigator 2 | 0.0645704 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0636697 |
| MSI2 | musashi RNA-binding protein 2 | 0.0625824 |
| RUNX1 | runt-related transcription factor 1 | 0.0614058 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.057527 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0566347 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0551504 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0545932 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0544265 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0539091 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0538039 |
| GPC6 | glypican 6 | 0.052756 |
| COL5A2 | collagen, type V, alpha 2 | 0.0526705 |
| ENO1 | enolase 1, (alpha) | 0.0501198 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0488255 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0484738 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0483814 |
| FSTL1 | follistatin-like 1 | 0.0482345 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0473027 |
| CD109 | CD109 molecule | 0.0467463 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0464232 |
| PRELID2 | PRELI domain containing 2 | 0.0463074 |
| PKM | pyruvate kinase, muscle | 0.0453447 |
| ZNF292 | zinc finger protein 292 | 0.0450845 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0450355 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0448824 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0447914 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0445921 |
| AFDN | afadin, adherens junction formation factor | 0.0442061 |
| CDH13 | cadherin 13 | 0.0441042 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0440303 |
| TMSB4X | thymosin beta 4, X-linked | 0.0438638 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.043758 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0435328 |
| SQSTM1 | sequestosome 1 | 0.042904 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0427973 |
| FLNB | filamin B, beta | 0.0426156 |
| OGA | O-GlcNAcase | 0.0420637 |
| FMNL2 | formin-like 2 | 0.0417741 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0417556 |
| GOLGA4 | golgin A4 | 0.0416244 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0415087 |
| INSIG2 | insulin induced gene 2 | 0.0414299 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0412789 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0404666 |
| LDHA | lactate dehydrogenase A | 0.0395527 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0394009 |
| COL5A1 | collagen, type V, alpha 1 | 0.0386708 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0384569 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0384398 |
| DSPP | dentin sialophosphoprotein | 0.0383936 |
| MMP12 | matrix metallopeptidase 12 | 0.0381531 |
| YEATS2 | YEATS domain containing 2 | 0.0374626 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0374381 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0364826 |
| HELZ | helicase with zinc finger | 0.0363646 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0361268 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0356525 |
| FAM107B | family with sequence similarity 107, member B | 0.0353708 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0342902 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0341408 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0340929 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0340772 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0340272 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0332776 |
| OPTN | optineurin | 0.0332426 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.032955 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0327262 |
| DENND5A | DENN/MADD domain containing 5A | 0.0322652 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0316909 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0316254 |
| PGK1 | phosphoglycerate kinase 1 | 0.0313748 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0313327 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0312018 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.178986 |
| VIM | vimentin | -0.16531 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.118692 |
| TMSB10 | thymosin beta 10 | -0.0953134 |
| MYADM | myeloid-associated differentiation marker | -0.0829571 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0818351 |
| MAP1B | microtubule-associated protein 1B | -0.0805542 |
| MT2A | metallothionein 2A | -0.0696136 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0545343 |
| MX2 | MX dynamin-like GTPase 2 | -0.0478618 |
| B2M | beta-2-microglobulin | -0.046399 |
| S100A10 | S100 calcium binding protein A10 | -0.0448005 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0426097 |
| POTEF | POTE ankyrin domain family, member F | -0.0415167 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.037917 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0349454 |
| HLA-B | major histocompatibility complex, class I, B | -0.0347269 |
| SUCNR1 | succinate receptor 1 | -0.034395 |
| PFN1 | profilin 1 | -0.0341698 |
| S100A6 | S100 calcium binding protein A6 | -0.034162 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0321019 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0288643 |
| SMIM44 | small integral membrane protein 44 | -0.0281444 |
| PLAT | plasminogen activator, tissue | -0.0272266 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0270025 |
| LOC112694756 | uncharaterized LOC112694756 | -0.026662 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0258547 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0252522 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0236931 |
| RPL28 | ribosomal protein L28 | -0.0234947 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0234398 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0234339 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0229063 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0224131 |
| BSG | basigin (Ok blood group) | -0.0222144 |
| HLA-C | major histocompatibility complex, class I, C | -0.0221491 |
| GNAS | GNAS complex locus | -0.0216601 |
| DCLK2 | doublecortin-like kinase 2 | -0.0216352 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0214207 |
| FTL | ferritin, light polypeptide | -0.0211607 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0208466 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0207531 |
| NDRG1 | N-myc downstream regulated 1 | -0.0204188 |
| TAPBP | TAP binding protein (tapasin) | -0.0203825 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.020338 |
| RPS15 | ribosomal protein S15 | -0.0200741 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0200065 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0190825 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0190064 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0189749 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0187881 |
| WBP2 | WW domain binding protein 2 | -0.0185712 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.018522 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0185171 |
| RIGI | RNA sensor RIG-I | -0.0184421 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0179698 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0179574 |
| MEIS2 | Meis homeobox 2 | -0.0178329 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0173478 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0172813 |
| NPR2 | natriuretic peptide receptor 2 | -0.017192 |
| RTN4 | reticulon 4 | -0.016953 |
| S100A11 | S100 calcium binding protein A11 | -0.0168965 |
| VKORC1 | vitamin K epoxide reductase complex, subunit 1 | -0.0163505 |
| H3-3B | H3.3 histone B | -0.0163253 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0160365 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0159 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0155966 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0155156 |
| ZNF609 | zinc finger protein 609 | -0.0154032 |
| KIF18B | kinesin family member 18B | -0.0153648 |
| S100A9 | S100 calcium binding protein A9 | -0.0152847 |
| CD44 | CD44 molecule (Indian blood group) | -0.0150345 |
| KIF2A | kinesin heavy chain member 2A | -0.0149875 |
| LAMA5 | laminin, alpha 5 | -0.0149587 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0147697 |
| ACTG1 | actin gamma 1 | -0.014751 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | -0.0145003 |
| CCND1 | cyclin D1 | -0.0144551 |
| CSTB | cystatin B (stefin B) | -0.0144152 |
| AGRN | agrin | -0.0144049 |
| DSTN | destrin (actin depolymerizing factor) | -0.0143628 |
| PMP22 | peripheral myelin protein 22 | -0.014209 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0140121 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.014012 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.013922 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0139033 |
| SEPTIN7 | septin 7 | -0.0136906 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0136528 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0135076 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0131777 |
| GSE1 | Gse1 coiled-coil protein | -0.0130975 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.013047 |
| ECM1 | extracellular matrix protein 1 | -0.0130306 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0129586 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0128076 |
| CAPNS1 | calpain, small subunit 1 | -0.0127324 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0125919 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0125122 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0123705 |
