| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0884969 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0879023 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0804865 |
| AREG | amphiregulin | 0.0692182 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0575117 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0527784 |
| KIF5B | kinesin family member 5B | 0.0526306 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0468359 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0459853 |
| NEK7 | NIMA-related kinase 7 | 0.0456596 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0444059 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0416703 |
| CCNL1 | cyclin L1 | 0.0414836 |
| XPO1 | exportin 1 | 0.04139 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0412846 |
| GASK1B | golgi associated kinase 1B | 0.0403937 |
| ZNF292 | zinc finger protein 292 | 0.0400026 |
| THOC1 | THO complex 1 | 0.039041 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0373206 |
| YEATS2 | YEATS domain containing 2 | 0.0364723 |
| MATR3 | matrin 3 | 0.0363613 |
| CPOX | coproporphyrinogen oxidase | 0.0358705 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0357474 |
| RPL41 | ribosomal protein L41 | 0.0353678 |
| TXNRD1 | thioredoxin reductase 1 | 0.034916 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0347086 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0345844 |
| YBX1 | Y box binding protein 1 | 0.0340185 |
| TNPO1 | transportin 1 | 0.0328436 |
| CEP95 | centrosomal protein 95kDa | 0.0326181 |
| OGA | O-GlcNAcase | 0.0325253 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0323321 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0318219 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0310706 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.030709 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0304343 |
| TMEM41B | transmembrane protein 41B | 0.0304105 |
| MGAT4C | MGAT4 family, member C | 0.0301646 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0301036 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0299115 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0298623 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0297903 |
| ZNF217 | zinc finger protein 217 | 0.0296856 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0293239 |
| ANXA1 | annexin A1 | 0.0293086 |
| PCM1 | pericentriolar material 1 | 0.0287079 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0284171 |
| NUP58 | nucleoporin 58 | 0.0280278 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0271125 |
| RPL4 | ribosomal protein L4 | 0.0269611 |
| ECT2 | epithelial cell transforming 2 | 0.0266836 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0265278 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0263803 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0262746 |
| NCKAP1 | NCK-associated protein 1 | 0.0260604 |
| CLTC | clathrin, heavy chain (Hc) | 0.02599 |
| KLHL24 | kelch-like family member 24 | 0.0257032 |
| ARRDC3 | arrestin domain containing 3 | 0.0255235 |
| TPR | translocated promoter region, nuclear basket protein | 0.025473 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0254695 |
| ATP11A | ATPase, class VI, type 11A | 0.0253506 |
| CEP192 | centrosomal protein 192kDa | 0.0252715 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0250951 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0249978 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0249511 |
| PNN | pinin, desmosome associated protein | 0.0240557 |
| PREPL | prolyl endopeptidase-like | 0.0240467 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0239785 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0237493 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0234924 |
| CLDND1 | claudin domain containing 1 | 0.0233214 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0232805 |
| AFDN | afadin, adherens junction formation factor | 0.0231365 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0228458 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.02266 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0224661 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.02241 |
| EZR | ezrin | 0.0223003 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0220229 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0218964 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0215882 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0215066 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0214477 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0214349 |
| H1-0 | H1.0 linker histone | 0.0213923 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0213433 |
| PCBP2 | poly(rC) binding protein 2 | 0.0209679 |
| ATP11B | ATPase, class VI, type 11B | 0.020897 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 | 0.0208794 |
| YTHDC1 | YTH domain containing 1 | 0.0208167 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0207741 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0207099 |
| NKTR | natural killer cell triggering receptor | 0.0204346 |
| HLTF | helicase-like transcription factor | 0.0203654 |
| THOC2 | THO complex 2 | 0.020317 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0202767 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0202738 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0200397 |
| EPHA6 | EPH receptor A6 | 0.0200289 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0199584 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.274713 |
| NLGN1 | neuroligin 1 | -0.235056 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.194443 |
| HMGA2 | high mobility group AT-hook 2 | -0.183699 |
| VIM | vimentin | -0.134928 |
| PCDH7 | protocadherin 7 | -0.0906755 |
| EHBP1 | EH domain binding protein 1 | -0.090419 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0821768 |
| EGR1 | early growth response 1 | -0.0751168 |
| ACTG1 | actin gamma 1 | -0.0738161 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0726375 |
| YAP1 | Yes-associated protein 1 | -0.0726359 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0698683 |
| INTS6 | integrator complex subunit 6 | -0.0681509 |
| ZNF804A | zinc finger protein 804A | -0.0679291 |
| NHSL1 | NHS-like 1 | -0.0678875 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0669143 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0663082 |
| RASAL2 | RAS protein activator like 2 | -0.0637311 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0615927 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0587406 |
| TMSB10 | thymosin beta 10 | -0.0572672 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0546772 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0542316 |
| ADIPOR2 | adiponectin receptor 2 | -0.0539534 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0537187 |
| DPYD | dihydropyrimidine dehydrogenase | -0.052316 |
| JMJD1C | jumonji domain containing 1C | -0.0498599 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0473775 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.04704 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0464339 |
| PTMA | prothymosin, alpha | -0.0454848 |
| CUX1 | cut-like homeobox 1 | -0.0428592 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0425831 |
| CMIP | c-Maf inducing protein | -0.0412383 |
| TUBA1B | tubulin, alpha 1b | -0.040253 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0401203 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0396688 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0393384 |
| ASPH | aspartate beta-hydroxylase | -0.0388689 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0386036 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0362975 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0361035 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0350926 |
| LRRC23 | leucine rich repeat containing 23 | -0.034965 |
| NABP1 | nucleic acid binding protein 1 | -0.0348694 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0343612 |
| FTL | ferritin, light polypeptide | -0.0343162 |
| CEP112 | centrosomal protein 112kDa | -0.0338323 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0337787 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0333579 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0327625 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0321655 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0321262 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0320192 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | -0.0316822 |
| EDARADD | EDAR-associated death domain | -0.03161 |
| NAV3 | neuron navigator 3 | -0.0311747 |
| EXOC4 | exocyst complex component 4 | -0.0309252 |
| MMP12 | matrix metallopeptidase 12 | -0.0307542 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0305048 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0303852 |
| TBCA | tubulin folding cofactor A | -0.0302354 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0299958 |
| SETX | senataxin | -0.0299471 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0295661 |
| R3HDM2 | R3H domain containing 2 | -0.0295088 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0294164 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0289365 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0285659 |
| RCOR1 | REST corepressor 1 | -0.0285294 |
| COMMD10 | COMM domain containing 10 | -0.0285016 |
| BPTF | bromodomain PHD finger transcription factor | -0.0283925 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0283797 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0282418 |
| MYPN | myopalladin | -0.0279948 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0279151 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.027494 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | -0.0272788 |
| ETV6 | ets variant 6 | -0.0269571 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0263511 |
| BCHE | butyrylcholinesterase | -0.0259221 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0255628 |
| MTAP | methylthioadenosine phosphorylase | -0.0250784 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0248516 |
| CCND1 | cyclin D1 | -0.0246836 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0246761 |
| PCDH9 | protocadherin 9 | -0.0245714 |
| RPL35A | ribosomal protein L35a | -0.0244727 |
| HMGA1 | high mobility group AT-hook 1 | -0.0241588 |
| UBAP2 | ubiquitin associated protein 2 | -0.0240853 |
| EGFR | epidermal growth factor receptor | -0.0240504 |
| RPS8 | ribosomal protein S8 | -0.0238937 |
| RSU1 | Ras suppressor protein 1 | -0.0238589 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0237609 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0237321 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0236672 |
| RAB10 | RAB10, member RAS oncogene family | -0.0236528 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0235597 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0234729 |
