| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.325129 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.114857 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.103738 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0939396 |
| LPIN1 | lipin 1 | 0.0862956 |
| HELZ | helicase with zinc finger | 0.0789518 |
| FAM13A | family with sequence similarity 13, member A | 0.0642074 |
| MSI2 | musashi RNA-binding protein 2 | 0.0637231 |
| POTEF | POTE ankyrin domain family, member F | 0.0605926 |
| WAC | WW domain containing adaptor with coiled-coil | 0.057832 |
| HMGB2 | high mobility group box 2 | 0.0532161 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0532076 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0503646 |
| PKM | pyruvate kinase, muscle | 0.0498774 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0495022 |
| RPL4 | ribosomal protein L4 | 0.0474858 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0466005 |
| COL3A1 | collagen, type III, alpha 1 | 0.0464244 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0454141 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.043844 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0435063 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0432337 |
| DTNA | dystrobrevin, alpha | 0.0430472 |
| ANXA2 | annexin A2 | 0.0422839 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0420258 |
| XPO1 | exportin 1 | 0.0409488 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0403497 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0403075 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0398507 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0394082 |
| APP | amyloid beta (A4) precursor protein | 0.0393884 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.039046 |
| CLTC | clathrin, heavy chain (Hc) | 0.0389134 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0383629 |
| TRIB2 | tribbles pseudokinase 2 | 0.0383036 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0382454 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.037568 |
| RPL23 | ribosomal protein L23 | 0.0369948 |
| WDR45B | WD repeat domain 45B | 0.0368623 |
| ZNF292 | zinc finger protein 292 | 0.0366344 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0364485 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0349236 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.034779 |
| PTMA | prothymosin, alpha | 0.0344551 |
| PGK1 | phosphoglycerate kinase 1 | 0.0342165 |
| SEPTIN9 | septin 9 | 0.0336249 |
| MATR3 | matrin 3 | 0.0335882 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0328973 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0328738 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0325397 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0321892 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0320263 |
| PTK2 | protein tyrosine kinase 2 | 0.031897 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0314563 |
| NCKAP1 | NCK-associated protein 1 | 0.0314151 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0313748 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0312626 |
| RNF145 | ring finger protein 145 | 0.0312436 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0309248 |
| MYO6 | myosin VI | 0.0308094 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.0304959 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0300862 |
| WDR43 | WD repeat domain 43 | 0.030072 |
| QKI | QKI, KH domain containing, RNA binding | 0.0300678 |
| PHIP | pleckstrin homology domain interacting protein | 0.0299195 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0297544 |
| ENO1 | enolase 1, (alpha) | 0.02954 |
| FOXO3 | forkhead box O3 | 0.0293947 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0293762 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0292547 |
| SET | SET nuclear proto-oncogene | 0.028695 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.0286163 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0282196 |
| RPL41 | ribosomal protein L41 | 0.028167 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0278719 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.027464 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0273318 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0273143 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.0272408 |
| MED13L | mediator complex subunit 13-like | 0.0271468 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0269495 |
| OLA1 | Obg-like ATPase 1 | 0.0268878 |
| CASC3 | cancer susceptibility candidate 3 | 0.0265308 |
| RPS6 | ribosomal protein S6 | 0.0262936 |
| CCNY | cyclin Y | 0.0260564 |
| PCBP2 | poly(rC) binding protein 2 | 0.0260504 |
| RPL35A | ribosomal protein L35a | 0.026027 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0259688 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0259078 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0257814 |
| TBX2 | T-box 2 | 0.0256089 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0255762 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0251131 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0249974 |
| SLMAP | sarcolemma associated protein | 0.0249631 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | 0.0249572 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0249153 |
| MORF4L1 | mortality factor 4 like 1 | 0.0248529 |
| SRPK2 | SRSF protein kinase 2 | 0.0247156 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.024387 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.472065 |
| NRG1 | neuregulin 1 | -0.15726 |
| SYT1 | synaptotagmin I | -0.090319 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0856067 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0834678 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0750905 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0564189 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0560464 |
| GDF15 | growth differentiation factor 15 | -0.0537865 |
| PLAT | plasminogen activator, tissue | -0.051849 |
| STC1 | stanniocalcin 1 | -0.0517954 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0515469 |
| BPTF | bromodomain PHD finger transcription factor | -0.0487152 |
| GPC5 | glypican 5 | -0.0484882 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0482686 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0446489 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0425202 |
| ZNF804A | zinc finger protein 804A | -0.0394862 |
| EXOC4 | exocyst complex component 4 | -0.0373971 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0367424 |
| MBTD1 | mbt domain containing 1 | -0.0356198 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0351701 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0347962 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0347396 |
| NBEA | neurobeachin | -0.0336571 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0333698 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0331559 |
| PCDH9 | protocadherin 9 | -0.0327911 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0323258 |
| AHR | aryl hydrocarbon receptor | -0.0321119 |
| MCL1 | myeloid cell leukemia 1 | -0.0312583 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0312395 |
| EPHA3 | EPH receptor A3 | -0.030955 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0302874 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0298805 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0298208 |
| SRP54 | signal recognition particle 54kDa | -0.0293659 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0293407 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0292935 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0290373 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0287087 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0285388 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0280842 |
| LRRC7 | leucine rich repeat containing 7 | -0.0280192 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0277626 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0274943 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0274573 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.027146 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0267426 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0264658 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0263212 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0261975 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0256388 |
| ATM | ATM serine/threonine kinase | -0.0256009 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0255538 |
| RTN4 | reticulon 4 | -0.0243994 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0240199 |
| AEBP2 | AE binding protein 2 | -0.023704 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0236 |
| CADM2 | cell adhesion molecule 2 | -0.0235325 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0235119 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0231186 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.022527 |
| COL4A6 | collagen, type IV, alpha 6 | -0.0223506 |
| ANGPT1 | angiopoietin 1 | -0.0222946 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0222415 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.022055 |
| HMGA2 | high mobility group AT-hook 2 | -0.0220294 |
| FRMD4A | FERM domain containing 4A | -0.0220248 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0219069 |
| ATRNL1 | attractin-like 1 | -0.0215964 |
| RALYL | RALY RNA binding protein-like | -0.021558 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0212599 |
| COL1A1 | collagen, type I, alpha 1 | -0.0209336 |
| NEK1 | NIMA-related kinase 1 | -0.0208325 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.020406 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0203247 |
| VCL | vinculin | -0.0202752 |
| HMGA1 | high mobility group AT-hook 1 | -0.0202729 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0202188 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0201728 |
| TBCK | TBC1 domain containing kinase | -0.0199467 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0198793 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.019851 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0197985 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0197518 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0197266 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.019717 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.019712 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.0196977 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0196951 |
| DGKH | diacylglycerol kinase, eta | -0.0196807 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0195716 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.019385 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0193033 |
| PRPF3 | pre-mRNA processing factor 3 | -0.0192584 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0191583 |
| FNIP1 | folliculin interacting protein 1 | -0.0190466 |
| DIAPH2 | diaphanous-related formin 2 | -0.0190349 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0185747 |
