| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PKM | pyruvate kinase, muscle | 0.163496 |
| TXNIP | thioredoxin interacting protein | 0.156016 |
| FNDC3B | fibronectin type III domain containing 3B | 0.130754 |
| ENO1 | enolase 1, (alpha) | 0.116756 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.111838 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.106771 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.103264 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0916833 |
| NDRG1 | N-myc downstream regulated 1 | 0.086275 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0823198 |
| DSPP | dentin sialophosphoprotein | 0.0817507 |
| CANX | calnexin | 0.078289 |
| FNDC3A | fibronectin type III domain containing 3A | 0.073357 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0732239 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.069701 |
| CALR | calreticulin | 0.068609 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0673779 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0672315 |
| ASPH | aspartate beta-hydroxylase | 0.0653154 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0634243 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0619431 |
| FAT1 | FAT atypical cadherin 1 | 0.0606574 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.059416 |
| HELZ | helicase with zinc finger | 0.0589384 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0582208 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0580921 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0576635 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0569832 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0562847 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0551099 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0545658 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0541655 |
| SCFD1 | sec1 family domain containing 1 | 0.0525487 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0525419 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0521706 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0508751 |
| HYOU1 | hypoxia up-regulated 1 | 0.0508442 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0505061 |
| PHF3 | PHD finger protein 3 | 0.0499694 |
| LDHA | lactate dehydrogenase A | 0.0498053 |
| GOLGB1 | golgin B1 | 0.0493437 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0488392 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0486605 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0481087 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0461848 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0461682 |
| COG6 | component of oligomeric golgi complex 6 | 0.0461084 |
| ZNF292 | zinc finger protein 292 | 0.0459219 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0456541 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0448897 |
| VEGFA | vascular endothelial growth factor A | 0.0447139 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0444723 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0436869 |
| LIMA1 | LIM domain and actin binding 1 | 0.0416378 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0415877 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0411871 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0406558 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0405804 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0404548 |
| MED13 | mediator complex subunit 13 | 0.0402302 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0398131 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0392748 |
| ABHD2 | abhydrolase domain containing 2 | 0.0391305 |
| PRRC2C | proline-rich coiled-coil 2C | 0.038884 |
| COPA | coatomer protein complex, subunit alpha | 0.0376612 |
| AREG | amphiregulin | 0.0376238 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0373198 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0372746 |
| PCED1B | PC-esterase domain containing 1B | 0.0366533 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0363637 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0363537 |
| RNF145 | ring finger protein 145 | 0.0359646 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.035893 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0355257 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0355173 |
| SSH2 | slingshot protein phosphatase 2 | 0.0353186 |
| ERCC5 | excision repair cross-complementation group 5 | 0.03524 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0349597 |
| CLTC | clathrin, heavy chain (Hc) | 0.0349022 |
| KIF16B | kinesin family member 16B | 0.0347647 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0346955 |
| PLSCR2 | phospholipid scramblase 2 | 0.033825 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0337534 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.033619 |
| SSR1 | signal sequence receptor, alpha | 0.0333057 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0330993 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0328551 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0325088 |
| SFTPA2 | surfactant protein A2 | 0.0324003 |
| TBPL1 | TBP-like 1 | 0.0321996 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0321118 |
| MSI2 | musashi RNA-binding protein 2 | 0.0319675 |
| SEPTIN9 | septin 9 | 0.0318013 |
| SBF2 | SET binding factor 2 | 0.0317458 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0317102 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0314868 |
| FNIP1 | folliculin interacting protein 1 | 0.0314496 |
| SRP54 | signal recognition particle 54kDa | 0.031188 |
| ARRDC3 | arrestin domain containing 3 | 0.0306423 |
| COG3 | component of oligomeric golgi complex 3 | 0.0303337 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.0906087 |
| HLA-B | major histocompatibility complex, class I, B | -0.0851814 |
| SPATA13 | spermatogenesis associated 13 | -0.0813665 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0797343 |
| PTMA | prothymosin, alpha | -0.0727502 |
| EPHB2 | EPH receptor B2 | -0.0669468 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0625978 |
| LMO7 | LIM domain 7 | -0.0625765 |
| PLSCR1 | phospholipid scramblase 1 | -0.0603053 |
| MYO1E | myosin IE | -0.0593683 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0578186 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0552137 |
| XAF1 | XIAP associated factor 1 | -0.0538254 |
| EGR1 | early growth response 1 | -0.0536061 |
| RIGI | RNA sensor RIG-I | -0.0518024 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0514398 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0512593 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0476555 |
| MX2 | MX dynamin-like GTPase 2 | -0.047449 |
| IRF1 | interferon regulatory factor 1 | -0.0466728 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0457716 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0441277 |
| MKI67 | marker of proliferation Ki-67 | -0.0433118 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0419581 |
| VCL | vinculin | -0.0407865 |
| EZR | ezrin | -0.0403452 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0402264 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0396937 |
| HLA-C | major histocompatibility complex, class I, C | -0.0390744 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0389644 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0366617 |
| H1-0 | H1.0 linker histone | -0.0365064 |
| FOXP1 | forkhead box P1 | -0.0360182 |
| NCKAP5 | NCK-associated protein 5 | -0.0355366 |
| TJP1 | tight junction protein 1 | -0.0344899 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0340667 |
| TMEM62 | transmembrane protein 62 | -0.0340256 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0334014 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0332578 |
| BRCA2 | breast cancer 2, early onset | -0.0331029 |
| ITGA6 | integrin, alpha 6 | -0.0325426 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0321421 |
| MAP7 | microtubule-associated protein 7 | -0.0309728 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0308008 |
| HLA-E | major histocompatibility complex, class I, E | -0.0307857 |
| RNF43 | ring finger protein 43 | -0.030775 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0306213 |
| SP100 | SP100 nuclear antigen | -0.0302622 |
| HMGB1 | high mobility group box 1 | -0.0302056 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0294734 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0283642 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0278624 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0276985 |
| LCN2 | lipocalin 2 | -0.0275774 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0275519 |
| TMSB10 | thymosin beta 10 | -0.0268748 |
| RPS24 | ribosomal protein S24 | -0.0266278 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0258843 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0254892 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0248107 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0247112 |
| H3-3B | H3.3 histone B | -0.0244041 |
| YBX3 | Y box binding protein 3 | -0.0241754 |
| DIAPH3 | diaphanous-related formin 3 | -0.0237904 |
| CDK6 | cyclin-dependent kinase 6 | -0.0237562 |
| TMC5 | transmembrane channel-like 5 | -0.0237263 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | -0.0236199 |
| ANXA1 | annexin A1 | -0.0227872 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0227444 |
| DEK | DEK proto-oncogene | -0.0224468 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0224375 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0224017 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0223059 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0218272 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0212908 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0212887 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0211987 |
| MECOM | MDS1 and EVI1 complex locus | -0.0210632 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0210303 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0208354 |
| CLYBL | citrate lyase beta like | -0.0207682 |
| SDC4 | syndecan 4 | -0.0207665 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0205893 |
| PMP22 | peripheral myelin protein 22 | -0.020509 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0204505 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0204438 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0203499 |
| TTC39B | tetratricopeptide repeat domain 39B | -0.0203349 |
| ZNRF3 | zinc and ring finger 3 | -0.0201778 |
| GPX2 | glutathione peroxidase 2 | -0.0201759 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0199729 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | -0.019863 |
| SQSTM1 | sequestosome 1 | -0.0198076 |
| LDLR | low density lipoprotein receptor | -0.0196797 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0196665 |
| KLF6 | Kruppel-like factor 6 | -0.019618 |
| CD44 | CD44 molecule (Indian blood group) | -0.0196093 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0195692 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0194763 |
| RASAL2 | RAS protein activator like 2 | -0.0193346 |
