| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.312049 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.265532 |
| FN1 | fibronectin 1 | 0.242391 |
| ENO1 | enolase 1, (alpha) | 0.135721 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.122775 |
| CD44 | CD44 molecule (Indian blood group) | 0.118782 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.117717 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0806227 |
| CALR | calreticulin | 0.0777045 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0775315 |
| ATP13A3 | ATPase type 13A3 | 0.0736186 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0689375 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0655836 |
| SMAD3 | SMAD family member 3 | 0.0607243 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0583993 |
| LOXL2 | lysyl oxidase-like 2 | 0.0551143 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0544172 |
| PKM | pyruvate kinase, muscle | 0.0541085 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0517695 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0512087 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0484829 |
| STC1 | stanniocalcin 1 | 0.0480814 |
| CENPF | centromere protein F, 350/400kDa | 0.0454289 |
| MTSS1 | metastasis suppressor 1 | 0.0452249 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0442705 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0436272 |
| LDHA | lactate dehydrogenase A | 0.0432558 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.04323 |
| ARRDC3 | arrestin domain containing 3 | 0.0416342 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0410765 |
| PRELID2 | PRELI domain containing 2 | 0.0408058 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0401174 |
| FAT1 | FAT atypical cadherin 1 | 0.0389003 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.038384 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0381808 |
| VEGFA | vascular endothelial growth factor A | 0.0380517 |
| DST | dystonin | 0.0363787 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0361625 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.036004 |
| APP | amyloid beta (A4) precursor protein | 0.0359259 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0357427 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0338842 |
| MSN | moesin | 0.0319973 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0315946 |
| INHBA | inhibin, beta A | 0.0314494 |
| ASPH | aspartate beta-hydroxylase | 0.0303364 |
| NAV2 | neuron navigator 2 | 0.0302803 |
| POSTN | periostin, osteoblast specific factor | 0.0299818 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0293559 |
| SEPTIN9 | septin 9 | 0.0284475 |
| VCAN | versican | 0.0282786 |
| HAS2 | hyaluronan synthase 2 | 0.0281982 |
| TMSB4X | thymosin beta 4, X-linked | 0.0275661 |
| RPN1 | ribophorin I | 0.0274907 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0267534 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0265107 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0262029 |
| ANLN | anillin, actin binding protein | 0.0261089 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0258106 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0255352 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0253897 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0253699 |
| MKI67 | marker of proliferation Ki-67 | 0.0251499 |
| YEATS2 | YEATS domain containing 2 | 0.0250341 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0249117 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0248788 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0246435 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0245148 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0239731 |
| VMP1 | vacuole membrane protein 1 | 0.02379 |
| ADM | adrenomedullin | 0.0236985 |
| DSPP | dentin sialophosphoprotein | 0.0235456 |
| ANO6 | anoctamin 6 | 0.0235285 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0232802 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0229747 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0224039 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0222837 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0218705 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0212821 |
| RARB | retinoic acid receptor, beta | 0.0212372 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0209517 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0209131 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0203251 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0195913 |
| CANX | calnexin | 0.0195636 |
| COL6A2 | collagen, type VI, alpha 2 | 0.019451 |
| TPR | translocated promoter region, nuclear basket protein | 0.0192973 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0190616 |
| MAP1B | microtubule-associated protein 1B | 0.0188733 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0188702 |
| KIAA1217 | KIAA1217 | 0.0187992 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0186566 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0184837 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0184571 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0183325 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0183058 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.018301 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0179782 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0178057 |
| TLN1 | talin 1 | 0.0177613 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.237194 |
| NDRG1 | N-myc downstream regulated 1 | -0.212509 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.200788 |
| COL1A1 | collagen, type I, alpha 1 | -0.193962 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.134933 |
| VIM | vimentin | -0.117157 |
| CADM1 | cell adhesion molecule 1 | -0.0663583 |
| TMSB10 | thymosin beta 10 | -0.0658063 |
| ACTG1 | actin gamma 1 | -0.0654882 |
| IER3 | immediate early response 3 | -0.0584088 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0533482 |
| CDH13 | cadherin 13 | -0.0524691 |
| FTL | ferritin, light polypeptide | -0.0517158 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0491091 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0490956 |
| COL5A1 | collagen, type V, alpha 1 | -0.0470646 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.046487 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0458026 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0457296 |
| MTDH | metadherin | -0.0442453 |
| RRBP1 | ribosome binding protein 1 | -0.0416225 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0408769 |
| FBN1 | fibrillin 1 | -0.0384052 |
| GNAS | GNAS complex locus | -0.0376127 |
| RPS8 | ribosomal protein S8 | -0.0367871 |
| PTMA | prothymosin, alpha | -0.0362518 |
| COL1A2 | collagen, type I, alpha 2 | -0.0360564 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0357035 |
| RAB7A | RAB7A, member RAS oncogene family | -0.033843 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0335001 |
| RPL35A | ribosomal protein L35a | -0.0331578 |
| RPL28 | ribosomal protein L28 | -0.0329503 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0329382 |
| QKI | QKI, KH domain containing, RNA binding | -0.0323147 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0310642 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0302539 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0299886 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0299369 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0291902 |
| RPS6 | ribosomal protein S6 | -0.0289913 |
| HLA-B | major histocompatibility complex, class I, B | -0.0289211 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0288315 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0287354 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0284718 |
| S100A9 | S100 calcium binding protein A9 | -0.027912 |
| SEC24D | SEC24 family member D | -0.0278769 |
| CLINT1 | clathrin interactor 1 | -0.0277504 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.026594 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0262727 |
| CAVIN1 | caveolae associated protein 1 | -0.0261962 |
| RPL8 | ribosomal protein L8 | -0.0250286 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.024877 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0247982 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0244512 |
| RHEB | Ras homolog enriched in brain | -0.0244066 |
| LMNA | lamin A/C | -0.0243537 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0241636 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.024132 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0235457 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.023515 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0234256 |
| TMEM263 | transmembrane protein 263 | -0.0232708 |
| RPLP1 | ribosomal protein, large, P1 | -0.0228156 |
| SQSTM1 | sequestosome 1 | -0.0228139 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0226242 |
| NEK10 | NIMA-related kinase 10 | -0.0225795 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0223274 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0223031 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0222148 |
| EGR1 | early growth response 1 | -0.022207 |
| TFG | TRK-fused gene | -0.0222016 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0221802 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0217923 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0217736 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0216007 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0215378 |
| RPL5 | ribosomal protein L5 | -0.0214954 |
| RPS5 | ribosomal protein S5 | -0.0214368 |
| THY1 | Thy-1 cell surface antigen | -0.0208816 |
| CDK13 | cyclin-dependent kinase 13 | -0.0207994 |
| TMEM165 | transmembrane protein 165 | -0.0206751 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0206576 |
| AFF3 | AF4/FMR2 family, member 3 | -0.020618 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0205968 |
| RPL30 | ribosomal protein L30 | -0.0204779 |
| HM13 | histocompatibility (minor) 13 | -0.020421 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0203202 |
| RPS19 | ribosomal protein S19 | -0.0202027 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0201988 |
| WASF2 | WAS protein family, member 2 | -0.0200444 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0200037 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.01995 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0197157 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0195012 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.019482 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0193932 |
| RACK1 | receptor for activated C kinase 1 | -0.0193892 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0193738 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0189576 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.018531 |
