| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mozavaptan_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.212165 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.198656 |
| ENO1 | enolase 1, (alpha) | 0.171222 |
| C3 | complement component 3 | 0.145484 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.13151 |
| DSPP | dentin sialophosphoprotein | 0.0936885 |
| TF | transferrin | 0.0883105 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0827562 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0824941 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0775222 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0702087 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0694526 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0687801 |
| VEGFA | vascular endothelial growth factor A | 0.0601908 |
| LDHA | lactate dehydrogenase A | 0.0571934 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.054327 |
| DTNA | dystrobrevin, alpha | 0.0537115 |
| INSIG2 | insulin induced gene 2 | 0.0527919 |
| PLIN2 | perilipin 2 | 0.0506402 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0505407 |
| RPL41 | ribosomal protein L41 | 0.0480428 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.047201 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0471384 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0464193 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0445565 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0444964 |
| AFDN | afadin, adherens junction formation factor | 0.0438756 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0409551 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0401661 |
| MYO1B | myosin IB | 0.0394977 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0382215 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0380347 |
| TPM3 | tropomyosin 3 | 0.0359359 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.035621 |
| FAT1 | FAT atypical cadherin 1 | 0.0349831 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0347565 |
| TNS1 | tensin 1 | 0.0346679 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0345659 |
| NGLY1 | N-glycanase 1 | 0.0341518 |
| SPAG9 | sperm associated antigen 9 | 0.0340653 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0338986 |
| RPL3 | ribosomal protein L3 | 0.0337175 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0331915 |
| YTHDC1 | YTH domain containing 1 | 0.0329682 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0323787 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0323299 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0321463 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0311001 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0309615 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.030882 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0304291 |
| NCKAP1 | NCK-associated protein 1 | 0.0304153 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0302435 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0297772 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0297705 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0297208 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0296709 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0294983 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0290943 |
| ZNF292 | zinc finger protein 292 | 0.0290604 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 0.0287121 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0285135 |
| IGF2 | insulin-like growth factor 2 | 0.0282322 |
| FMNL2 | formin-like 2 | 0.0282063 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0277476 |
| FAM13A | family with sequence similarity 13, member A | 0.0273777 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0272422 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0272394 |
| PKM | pyruvate kinase, muscle | 0.0271842 |
| TPD52 | tumor protein D52 | 0.0270684 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0268922 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0268659 |
| ADM | adrenomedullin | 0.0265078 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0262424 |
| QKI | QKI, KH domain containing, RNA binding | 0.0253522 |
| MYO6 | myosin VI | 0.0247232 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0246506 |
| AHSG | alpha-2-HS-glycoprotein | 0.0243934 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0242967 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0239355 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0237229 |
| MSI2 | musashi RNA-binding protein 2 | 0.0236056 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0235036 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0233543 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0233184 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0232371 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0230487 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0229586 |
| PCBP2 | poly(rC) binding protein 2 | 0.0229087 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0228093 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.022761 |
| ARRDC3 | arrestin domain containing 3 | 0.0227467 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0225519 |
| WWC2 | WW and C2 domain containing 2 | 0.0221914 |
| EFNA1 | ephrin-A1 | 0.0218957 |
| NUP58 | nucleoporin 58 | 0.021795 |
| RBM33 | RNA binding motif protein 33 | 0.0217004 |
| ITGA6 | integrin, alpha 6 | 0.0214176 |
| RANBP9 | RAN binding protein 9 | 0.021331 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0212892 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GPC3 | glypican 3 | -0.114126 |
| APOB | apolipoprotein B | -0.109876 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.101787 |
| A2M | alpha-2-macroglobulin | -0.0948498 |
| FN1 | fibronectin 1 | -0.0942602 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0858949 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0812469 |
| EHBP1 | EH domain binding protein 1 | -0.0801325 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0795026 |
| RPS6 | ribosomal protein S6 | -0.0716125 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0709368 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0706049 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0660778 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0657505 |
| RPS24 | ribosomal protein S24 | -0.0652684 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0637301 |
| ITGAV | integrin, alpha V | -0.0625195 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0562581 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0558586 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0543289 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | -0.0537381 |
| PTCHD4 | patched domain containing 4 | -0.0524678 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0521775 |
| EGR1 | early growth response 1 | -0.051566 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0511008 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0503709 |
| RPL37A | ribosomal protein L37a | -0.0496193 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0487063 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0478338 |
| DOCK4 | dedicator of cytokinesis 4 | -0.047129 |
| GNAS | GNAS complex locus | -0.0465021 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0458423 |
| RPS8 | ribosomal protein S8 | -0.044939 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0439277 |
| RBM39 | RNA binding motif protein 39 | -0.0439083 |
| SMAD3 | SMAD family member 3 | -0.0437412 |
| ACTN4 | actinin, alpha 4 | -0.0436096 |
| RRBP1 | ribosome binding protein 1 | -0.043152 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0413474 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0410354 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0409863 |
| RPL31 | ribosomal protein L31 | -0.0395207 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0380874 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0379707 |
| IER3 | immediate early response 3 | -0.0372148 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0371902 |
| FTL | ferritin, light polypeptide | -0.0370529 |
| VCL | vinculin | -0.0360079 |
| RPLP1 | ribosomal protein, large, P1 | -0.0358105 |
| ZNF644 | zinc finger protein 644 | -0.0354747 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0354523 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0351171 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0345914 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.034543 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0344124 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.033911 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0338386 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0337763 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.033257 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0331798 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0329747 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0326585 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0324809 |
| MT2A | metallothionein 2A | -0.0323516 |
| GPC6 | glypican 6 | -0.0318811 |
| CHD6 | chromodomain helicase DNA binding protein 6 | -0.0315831 |
| RIGI | RNA sensor RIG-I | -0.031354 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.0309832 |
| RPS19 | ribosomal protein S19 | -0.0308695 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0308447 |
| WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | -0.0306388 |
| RPL38 | ribosomal protein L38 | -0.0306372 |
| ARL5A | ADP-ribosylation factor-like 5A | -0.03059 |
| NINL | ninein-like | -0.0303808 |
| CCDC146 | coiled-coil domain containing 146 | -0.0299268 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0298274 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0297395 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0296149 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0290961 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0290659 |
| GK | glycerol kinase | -0.0288867 |
| NPR2 | natriuretic peptide receptor 2 | -0.0287981 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0287104 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0286634 |
| TNS3 | tensin 3 | -0.0286541 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0285525 |
| PEG10 | paternally expressed 10 | -0.0283982 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0281612 |
| RUNX1 | runt-related transcription factor 1 | -0.0280862 |
| FRMD5 | FERM domain containing 5 | -0.0280271 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0280254 |
| FOXN3 | forkhead box N3 | -0.0279852 |
| APOE | apolipoprotein E | -0.0278176 |
| RPL26 | ribosomal protein L26 | -0.0277716 |
| CNKSR3 | CNKSR family member 3 | -0.0277064 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0276347 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0275376 |
| SYN3 | synapsin III | -0.0275077 |
| RBM25 | RNA binding motif protein 25 | -0.0272922 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0272124 |
