| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.168954 |
| ENO1 | enolase 1, (alpha) | 0.136465 |
| MYOF | myoferlin | 0.13616 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.130108 |
| FLNB | filamin B, beta | 0.12673 |
| MEF2A | myocyte enhancer factor 2A | 0.125756 |
| MTSS1 | metastasis suppressor 1 | 0.119742 |
| PODXL | podocalyxin-like | 0.111545 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0940238 |
| ASPH | aspartate beta-hydroxylase | 0.0746129 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0740293 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0693419 |
| SLK | STE20-like kinase | 0.0687693 |
| PLEC | plectin | 0.0673397 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0664268 |
| ANLN | anillin, actin binding protein | 0.0662693 |
| SMAD3 | SMAD family member 3 | 0.0644554 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0597257 |
| MYO10 | myosin X | 0.0595185 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0594664 |
| KIAA1217 | KIAA1217 | 0.0575041 |
| PKM | pyruvate kinase, muscle | 0.0573933 |
| MSN | moesin | 0.0572326 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0567103 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0560996 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0560862 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0559355 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0552765 |
| CUL4B | cullin 4B | 0.0551351 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0549619 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0548592 |
| ITGA6 | integrin, alpha 6 | 0.0534166 |
| TMSB4X | thymosin beta 4, X-linked | 0.0530841 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0526922 |
| CALR | calreticulin | 0.0510962 |
| NAV2 | neuron navigator 2 | 0.0501352 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0495603 |
| AMOTL1 | angiomotin like 1 | 0.0495174 |
| PRELID2 | PRELI domain containing 2 | 0.0494704 |
| TPM3 | tropomyosin 3 | 0.0493453 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0486806 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0478367 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0470323 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0458376 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0446957 |
| DST | dystonin | 0.0443352 |
| PGK1 | phosphoglycerate kinase 1 | 0.0441986 |
| CAPRIN2 | caprin family member 2 | 0.0434968 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0433626 |
| SPAG9 | sperm associated antigen 9 | 0.0425517 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0422067 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0415193 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0414217 |
| LMO7 | LIM domain 7 | 0.0410888 |
| EZR | ezrin | 0.0410066 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0407341 |
| APP | amyloid beta (A4) precursor protein | 0.0399573 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0391738 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0389916 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0388747 |
| CANX | calnexin | 0.0385419 |
| NUP58 | nucleoporin 58 | 0.0383132 |
| FNIP1 | folliculin interacting protein 1 | 0.0379368 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0378673 |
| SQLE | squalene epoxidase | 0.0378373 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0369409 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0368049 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0365554 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0364483 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0364387 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0363724 |
| PLS3 | plastin 3 | 0.0358598 |
| RAI14 | retinoic acid induced 14 | 0.0357124 |
| YEATS2 | YEATS domain containing 2 | 0.0354955 |
| SLTM | SAFB-like, transcription modulator | 0.0353443 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0351095 |
| ZNF292 | zinc finger protein 292 | 0.0348032 |
| ARRDC3 | arrestin domain containing 3 | 0.0347122 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0346408 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0345971 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0345696 |
| PTK2 | protein tyrosine kinase 2 | 0.0341998 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0340998 |
| MCL1 | myeloid cell leukemia 1 | 0.0337998 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0325523 |
| BLCAP | bladder cancer associated protein | 0.0325126 |
| LDHA | lactate dehydrogenase A | 0.0324327 |
| KRT6A | keratin 6A, type II | 0.0324287 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0320837 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0320304 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0318804 |
| JAG1 | jagged 1 | 0.0317569 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0316837 |
| RPL4 | ribosomal protein L4 | 0.0316396 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0315623 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0313312 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0311556 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0309145 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0308607 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0307616 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.2104 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.187698 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.12236 |
| TMSB10 | thymosin beta 10 | -0.0880704 |
| PTMA | prothymosin, alpha | -0.0853661 |
| S100A10 | S100 calcium binding protein A10 | -0.0769065 |
| MT2A | metallothionein 2A | -0.069742 |
| GNAS | GNAS complex locus | -0.0669794 |
| RPS21 | ribosomal protein S21 | -0.0639965 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0627695 |
| B2M | beta-2-microglobulin | -0.0602173 |
| HLA-B | major histocompatibility complex, class I, B | -0.0587522 |
| RPS6 | ribosomal protein S6 | -0.0549664 |
| NDRG1 | N-myc downstream regulated 1 | -0.0541342 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.053645 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0522865 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0516646 |
| RPS8 | ribosomal protein S8 | -0.0467119 |
| RPLP1 | ribosomal protein, large, P1 | -0.044814 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0447953 |
| IGF2 | insulin-like growth factor 2 | -0.0446315 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0413526 |
| RPS13 | ribosomal protein S13 | -0.0405883 |
| RPS24 | ribosomal protein S24 | -0.0391239 |
| RPS25 | ribosomal protein S25 | -0.0390661 |
| RPLP2 | ribosomal protein, large, P2 | -0.0380374 |
| RPS19 | ribosomal protein S19 | -0.0376225 |
| LAMA5 | laminin, alpha 5 | -0.0375393 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0373725 |
| FTL | ferritin, light polypeptide | -0.0357185 |
| MYADM | myeloid-associated differentiation marker | -0.0355612 |
| S100A9 | S100 calcium binding protein A9 | -0.034326 |
| S100A11 | S100 calcium binding protein A11 | -0.0329722 |
| HM13 | histocompatibility (minor) 13 | -0.0327098 |
| HMGA1 | high mobility group AT-hook 1 | -0.0323173 |
| RPL34 | ribosomal protein L34 | -0.0313012 |
| RPL28 | ribosomal protein L28 | -0.0312928 |
| STC1 | stanniocalcin 1 | -0.0307812 |
| RPL11 | ribosomal protein L11 | -0.0304198 |
| RPL8 | ribosomal protein L8 | -0.0301171 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.029878 |
| RPL27A | ribosomal protein L27a | -0.0296178 |
| RPL31 | ribosomal protein L31 | -0.0293504 |
| S100A2 | S100 calcium binding protein A2 | -0.0291261 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0286005 |
| RPS14 | ribosomal protein S14 | -0.0284095 |
| S100A6 | S100 calcium binding protein A6 | -0.0282547 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0277257 |
| RPL35A | ribosomal protein L35a | -0.0274492 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0273328 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0271054 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0269108 |
| RPS15 | ribosomal protein S15 | -0.0266986 |
| RPL12 | ribosomal protein L12 | -0.0265415 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0264501 |
| RPL36 | ribosomal protein L36 | -0.0260994 |
| RPLP0 | ribosomal protein, large, P0 | -0.0258945 |
| RPS23 | ribosomal protein S23 | -0.0255665 |
| DSTN | destrin (actin depolymerizing factor) | -0.0254632 |
| WASF2 | WAS protein family, member 2 | -0.024893 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0248015 |
| RPS29 | ribosomal protein S29 | -0.024687 |
| ASTN2 | astrotactin 2 | -0.0246645 |
| RPS5 | ribosomal protein S5 | -0.0245772 |
| GUK1 | guanylate kinase 1 | -0.0244144 |
| EGR1 | early growth response 1 | -0.0243524 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0242772 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0240114 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0237608 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0236716 |
| HLA-A | major histocompatibility complex, class I, A | -0.0235739 |
| FBXO11 | F-box protein 11 | -0.0232142 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0230684 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0229897 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0228165 |
| PFN1 | profilin 1 | -0.0226574 |
| RPL23 | ribosomal protein L23 | -0.0223003 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0221193 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.021955 |
| CSTB | cystatin B (stefin B) | -0.0219493 |
| ACTG1 | actin gamma 1 | -0.0219255 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0217924 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0217482 |
| EMP1 | epithelial membrane protein 1 | -0.021715 |
| RPL37A | ribosomal protein L37a | -0.0217082 |
| PALLD | palladin, cytoskeletal associated protein | -0.021703 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0216044 |
| RPL21 | ribosomal protein L21 | -0.0213616 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0211705 |
| CST3 | cystatin C | -0.0211307 |
| IFI44L | interferon-induced protein 44-like | -0.021051 |
| RPL32 | ribosomal protein L32 | -0.0209986 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0209643 |
| RPL36A | ribosomal protein L36a | -0.0209389 |
| RPS27 | ribosomal protein S27 | -0.0208608 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0206994 |
| PLTP | phospholipid transfer protein | -0.0205787 |
| S100A4 | S100 calcium binding protein A4 | -0.0202567 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0202481 |
| RPS16 | ribosomal protein S16 | -0.0201856 |
