| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.157275 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.102231 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0916697 |
| GOLGA4 | golgin A4 | 0.0911805 |
| HYOU1 | hypoxia up-regulated 1 | 0.0818444 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.08037 |
| TES | testin LIM domain protein | 0.0780619 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0655848 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0655269 |
| CLTC | clathrin, heavy chain (Hc) | 0.0580198 |
| TMSB4X | thymosin beta 4, X-linked | 0.0576162 |
| AREG | amphiregulin | 0.0571156 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0564761 |
| DSPP | dentin sialophosphoprotein | 0.056347 |
| RAB6A | RAB6A, member RAS oncogene family | 0.054689 |
| RPL35A | ribosomal protein L35a | 0.0541305 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0514139 |
| FAM13A | family with sequence similarity 13, member A | 0.0507913 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.049219 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0467353 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0462773 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0459544 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0457688 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.044958 |
| S100A6 | S100 calcium binding protein A6 | 0.0449264 |
| H1-0 | H1.0 linker histone | 0.0436054 |
| ANLN | anillin, actin binding protein | 0.0427436 |
| KRT19 | keratin 19, type I | 0.0420221 |
| RPLP0 | ribosomal protein, large, P0 | 0.0410245 |
| NUP58 | nucleoporin 58 | 0.0408661 |
| AGR2 | anterior gradient 2 | 0.040267 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0394712 |
| KRT18 | keratin 18, type I | 0.0392152 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0387473 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0382728 |
| POTEF | POTE ankyrin domain family, member F | 0.0378106 |
| ENO1 | enolase 1, (alpha) | 0.037475 |
| SRP54 | signal recognition particle 54kDa | 0.0374711 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.037203 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0371398 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0368095 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0366058 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0365807 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0362509 |
| ZNF292 | zinc finger protein 292 | 0.0361456 |
| RPN1 | ribophorin I | 0.0356148 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.0353182 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0349047 |
| SLK | STE20-like kinase | 0.034838 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | 0.0347416 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0345888 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0342447 |
| CANX | calnexin | 0.0341689 |
| ATF4 | activating transcription factor 4 | 0.0341238 |
| CD164 | CD164 molecule, sialomucin | 0.0341161 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0340997 |
| MUC17 | mucin 17, cell surface associated | 0.0337934 |
| MORF4L2 | mortality factor 4 like 2 | 0.0336605 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0332971 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0326206 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0323838 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0322771 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0321764 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0318531 |
| CLINT1 | clathrin interactor 1 | 0.0317823 |
| PGM3 | phosphoglucomutase 3 | 0.0313789 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0307199 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0307086 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0306557 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0304925 |
| RPL4 | ribosomal protein L4 | 0.0304598 |
| UBE4A | ubiquitination factor E4A | 0.030449 |
| WDR45B | WD repeat domain 45B | 0.0299755 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.029968 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0299201 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0296876 |
| DSG2 | desmoglein 2 | 0.0295166 |
| PKM | pyruvate kinase, muscle | 0.0292509 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.0291897 |
| RPL34 | ribosomal protein L34 | 0.0290831 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0290788 |
| SNX9 | sorting nexin 9 | 0.0289177 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.028449 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.027964 |
| COPA | coatomer protein complex, subunit alpha | 0.0276896 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0276747 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0275223 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0271319 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0270244 |
| PGK1 | phosphoglycerate kinase 1 | 0.0267577 |
| CTSE | cathepsin E | 0.0266084 |
| GOLPH3L | golgi phosphoprotein 3-like | 0.026555 |
| HM13 | histocompatibility (minor) 13 | 0.0264951 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0263799 |
| LDHA | lactate dehydrogenase A | 0.0263652 |
| RPS6 | ribosomal protein S6 | 0.0262878 |
| RPS2 | ribosomal protein S2 | 0.02626 |
| MEF2A | myocyte enhancer factor 2A | 0.0261949 |
| TMEM41B | transmembrane protein 41B | 0.0261645 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0260743 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.114104 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.094729 |
| UBC | ubiquitin C | -0.0882152 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0854471 |
| EMP1 | epithelial membrane protein 1 | -0.074448 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0728094 |
| AHNAK | AHNAK nucleoprotein | -0.0680164 |
| TMSB10 | thymosin beta 10 | -0.0654116 |
| EHBP1 | EH domain binding protein 1 | -0.0624584 |
| LMO7 | LIM domain 7 | -0.0617131 |
| PTMA | prothymosin, alpha | -0.058509 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0580608 |
| INTS6 | integrator complex subunit 6 | -0.0521458 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0517555 |
| RPS27A | ribosomal protein S27a | -0.0510294 |
| RNF213 | ring finger protein 213 | -0.0459797 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0447315 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0439489 |
| COBL | cordon-bleu WH2 repeat protein | -0.0432368 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0427757 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0425276 |
| FLNB | filamin B, beta | -0.0425165 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0413869 |
| EXOC4 | exocyst complex component 4 | -0.0406184 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0396151 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0383351 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0382724 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0378908 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0364102 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.035793 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0353865 |
| AHR | aryl hydrocarbon receptor | -0.0349632 |
| CDK6 | cyclin-dependent kinase 6 | -0.0339695 |
| ACTN4 | actinin, alpha 4 | -0.0337128 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.0334701 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0333702 |
| YAP1 | Yes-associated protein 1 | -0.0329426 |
| PCBP2 | poly(rC) binding protein 2 | -0.0323487 |
| HLA-E | major histocompatibility complex, class I, E | -0.0323357 |
| KRT8 | keratin 8, type II | -0.0321881 |
| CMIP | c-Maf inducing protein | -0.032155 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0319883 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0319498 |
| LMNA | lamin A/C | -0.031759 |
| TMC5 | transmembrane channel-like 5 | -0.031513 |
| ASPH | aspartate beta-hydroxylase | -0.0315108 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0313959 |
| FRMD5 | FERM domain containing 5 | -0.0310965 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0305589 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.03045 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0302861 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0301243 |
| RRM2 | ribonucleotide reductase M2 | -0.0298871 |
| RAD51B | RAD51 paralog B | -0.0297346 |
| EFNA5 | ephrin-A5 | -0.0296288 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0291093 |
| UBE3C | ubiquitin protein ligase E3C | -0.0280362 |
| FUS | FUS RNA binding protein | -0.027973 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0279492 |
| RNF43 | ring finger protein 43 | -0.0279244 |
| FOXO3 | forkhead box O3 | -0.0274883 |
| RUNX1 | runt-related transcription factor 1 | -0.0274115 |
| POF1B | premature ovarian failure, 1B | -0.0273373 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0272993 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0270292 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0269648 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0267565 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0267316 |
| BPTF | bromodomain PHD finger transcription factor | -0.0262135 |
| ETV6 | ets variant 6 | -0.0260649 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0260514 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0260105 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0259832 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0259237 |
| PRKCE | protein kinase C, epsilon | -0.0257471 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0255496 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0255247 |
| AOPEP | aminopeptidase O (putative) | -0.0254993 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0254105 |
| MYO1E | myosin IE | -0.0249429 |
| USP34 | ubiquitin specific peptidase 34 | -0.0248899 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0248719 |
| EXPH5 | exophilin 5 | -0.0245008 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0244867 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0244652 |
| JUN | jun proto-oncogene | -0.0244184 |
| RCOR1 | REST corepressor 1 | -0.0239721 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0239314 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0238734 |
| MYO1D | myosin ID | -0.0236513 |
| RASEF | RAS and EF-hand domain containing | -0.0234523 |
| PLSCR1 | phospholipid scramblase 1 | -0.0233767 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0233351 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0231833 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.023174 |
| CFAP161 | cilia and flagella associated protein 161 | -0.0229636 |
| RIGI | RNA sensor RIG-I | -0.0228759 |
| EFNB2 | ephrin-B2 | -0.0228305 |
| WWOX | WW domain containing oxidoreductase | -0.0228273 |
| NABP1 | nucleic acid binding protein 1 | -0.0226206 |
