| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSPP | dentin sialophosphoprotein | 0.109439 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.10415 |
| PKM | pyruvate kinase, muscle | 0.0963996 |
| ENO1 | enolase 1, (alpha) | 0.0960668 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0933814 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.090612 |
| TXNIP | thioredoxin interacting protein | 0.0848157 |
| CALR | calreticulin | 0.0811893 |
| FAT1 | FAT atypical cadherin 1 | 0.0801315 |
| RPS12 | ribosomal protein S12 | 0.0772112 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0713426 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0693442 |
| RNF145 | ring finger protein 145 | 0.0674121 |
| TNS4 | tensin 4 | 0.0643886 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0625552 |
| CALB1 | calbindin 1, 28kDa | 0.0621233 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0615328 |
| VEGFA | vascular endothelial growth factor A | 0.0600394 |
| LDHA | lactate dehydrogenase A | 0.0572401 |
| TPM3 | tropomyosin 3 | 0.0570922 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.056419 |
| CD164 | CD164 molecule, sialomucin | 0.0558216 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0550412 |
| NUP58 | nucleoporin 58 | 0.0540088 |
| FAM13A | family with sequence similarity 13, member A | 0.0517242 |
| ZNF292 | zinc finger protein 292 | 0.0516555 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0498031 |
| YBX1 | Y box binding protein 1 | 0.0497714 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0494647 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0460205 |
| MLEC | malectin | 0.0450504 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0447273 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0444421 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0434441 |
| RPS3 | ribosomal protein S3 | 0.0425582 |
| TMSB4X | thymosin beta 4, X-linked | 0.0423071 |
| ABHD2 | abhydrolase domain containing 2 | 0.0422964 |
| RREB1 | ras responsive element binding protein 1 | 0.0419859 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.041856 |
| EREG | epiregulin | 0.0411898 |
| POTEF | POTE ankyrin domain family, member F | 0.0403034 |
| SLK | STE20-like kinase | 0.0402872 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0401336 |
| RPL3 | ribosomal protein L3 | 0.039104 |
| HSPA8 | heat shock 70kDa protein 8 | 0.038283 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0380079 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0374628 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0366123 |
| RPS2 | ribosomal protein S2 | 0.0362319 |
| KRT19 | keratin 19, type I | 0.0355232 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0353993 |
| RPS17 | ribosomal protein S17 | 0.0343524 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0343392 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.034112 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0339279 |
| EHF | ets homologous factor | 0.0337455 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0335585 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.033338 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0333049 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.033283 |
| RAB6A | RAB6A, member RAS oncogene family | 0.033225 |
| NCKAP1 | NCK-associated protein 1 | 0.0329412 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0324542 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0324528 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0324356 |
| INSIG2 | insulin induced gene 2 | 0.0322866 |
| KRT18 | keratin 18, type I | 0.0321853 |
| MCL1 | myeloid cell leukemia 1 | 0.0320594 |
| YTHDC1 | YTH domain containing 1 | 0.0320082 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0312601 |
| CCNL1 | cyclin L1 | 0.0309989 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0303475 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0298079 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0292197 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0291001 |
| MED13L | mediator complex subunit 13-like | 0.0290821 |
| RPL41 | ribosomal protein L41 | 0.0290648 |
| VMP1 | vacuole membrane protein 1 | 0.0288951 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.028623 |
| AREG | amphiregulin | 0.0284774 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0284091 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0283429 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0282169 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.0282059 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0279853 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0277692 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0275975 |
| CCNY | cyclin Y | 0.0274593 |
| RPL4 | ribosomal protein L4 | 0.0267401 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0267103 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0266344 |
| FOSL1 | FOS-like antigen 1 | 0.0264228 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0262304 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0259887 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0255802 |
| LRRC1 | leucine rich repeat containing 1 | 0.0254231 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0253342 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0252469 |
| CD9 | CD9 molecule | 0.0252452 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0250039 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.45175 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.119311 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.097837 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0694109 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.066976 |
| PTMA | prothymosin, alpha | -0.0637183 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0572748 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0469891 |
| AGR2 | anterior gradient 2 | -0.0461446 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0437481 |
| MYO1E | myosin IE | -0.043155 |
| AHNAK | AHNAK nucleoprotein | -0.0421697 |
| RRBP1 | ribosome binding protein 1 | -0.0421639 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.039585 |
| ACTG1 | actin gamma 1 | -0.0391921 |
| RPS6 | ribosomal protein S6 | -0.0390179 |
| ANXA1 | annexin A1 | -0.0373667 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.03595 |
| GDF15 | growth differentiation factor 15 | -0.0356058 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0350928 |
| LMNA | lamin A/C | -0.0348378 |
| RPS24 | ribosomal protein S24 | -0.0347278 |
| CADPS | Ca++-dependent secretion activator | -0.0346727 |
| RPL28 | ribosomal protein L28 | -0.0344785 |
| POF1B | premature ovarian failure, 1B | -0.0340292 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0336494 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0333392 |
| SBF2 | SET binding factor 2 | -0.0327603 |
| S100A10 | S100 calcium binding protein A10 | -0.032684 |
| TMSB10 | thymosin beta 10 | -0.0325897 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0319588 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0319127 |
| HDLBP | high density lipoprotein binding protein | -0.0315187 |
| RPL8 | ribosomal protein L8 | -0.0314852 |
| NEBL | nebulette | -0.0314231 |
| HMGA1 | high mobility group AT-hook 1 | -0.0313148 |
| RPLP1 | ribosomal protein, large, P1 | -0.0305235 |
| CCND1 | cyclin D1 | -0.0303235 |
| OGA | O-GlcNAcase | -0.0301836 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0300821 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0297452 |
| RPL32 | ribosomal protein L32 | -0.0294824 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0293818 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0283042 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.02822 |
| RPS25 | ribosomal protein S25 | -0.028092 |
| GPHN | gephyrin | -0.0279043 |
| EMP1 | epithelial membrane protein 1 | -0.0278238 |
| EXPH5 | exophilin 5 | -0.0277733 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0276574 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0275825 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0273903 |
| RPS23 | ribosomal protein S23 | -0.0268582 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0268443 |
| RPS15 | ribosomal protein S15 | -0.0265871 |
| PATJ | PATJ crumbs cell polarity complex component | -0.026056 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0259777 |
| RPLP0 | ribosomal protein, large, P0 | -0.0259419 |
| ATXN1 | ataxin 1 | -0.0252972 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0249587 |
| FOXP1 | forkhead box P1 | -0.0249554 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | -0.0249524 |
| CCNI | cyclin I | -0.0248345 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0248052 |
| STK17A | serine/threonine kinase 17a | -0.024792 |
| AHI1 | Abelson helper integration site 1 | -0.0244475 |
| RPS8 | ribosomal protein S8 | -0.0242977 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0241247 |
| RPS21 | ribosomal protein S21 | -0.0240395 |
| GNAS | GNAS complex locus | -0.0240394 |
| ERBIN | erbb2 interacting protein | -0.0239082 |
| LMO7 | LIM domain 7 | -0.023561 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0234661 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0234475 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0233717 |
| EPCAM | epithelial cell adhesion molecule | -0.0230004 |
| TRIM2 | tripartite motif containing 2 | -0.0226881 |
| RORA | RAR-related orphan receptor A | -0.0224021 |
| IER3 | immediate early response 3 | -0.0222265 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0218613 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0217119 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0216266 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0216124 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0214092 |
| RPS11 | ribosomal protein S11 | -0.0213546 |
| RPL7A | ribosomal protein L7a | -0.0213286 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0212064 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.021138 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0210126 |
| RPS5 | ribosomal protein S5 | -0.0209675 |
| SHROOM3 | shroom family member 3 | -0.0206318 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0206175 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0205319 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0205014 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0203428 |
| OSBP | oxysterol binding protein | -0.0202981 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0202834 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0202481 |
| INSIG1 | insulin induced gene 1 | -0.020192 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0201191 |
