| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.135624 |
| DST | dystonin | 0.127411 |
| ENO1 | enolase 1, (alpha) | 0.11981 |
| POTEF | POTE ankyrin domain family, member F | 0.112278 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.111421 |
| TMSB4X | thymosin beta 4, X-linked | 0.105696 |
| MT2A | metallothionein 2A | 0.0836715 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0802019 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0772333 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0755475 |
| PKM | pyruvate kinase, muscle | 0.0710241 |
| CALR | calreticulin | 0.0677342 |
| CENPF | centromere protein F, 350/400kDa | 0.0624224 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0624151 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0622968 |
| RPS3 | ribosomal protein S3 | 0.060713 |
| EZR | ezrin | 0.0598235 |
| TXNIP | thioredoxin interacting protein | 0.059037 |
| SLK | STE20-like kinase | 0.0585666 |
| RPS12 | ribosomal protein S12 | 0.0564935 |
| TPM3 | tropomyosin 3 | 0.0559643 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0544329 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0517989 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0503129 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0495656 |
| CAPRIN2 | caprin family member 2 | 0.0489468 |
| LDHA | lactate dehydrogenase A | 0.0488166 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0468306 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.046332 |
| FMNL2 | formin-like 2 | 0.0455662 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0451746 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0417082 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0408055 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0402772 |
| NUP58 | nucleoporin 58 | 0.0400111 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0382205 |
| YBX1 | Y box binding protein 1 | 0.0378654 |
| RPL3 | ribosomal protein L3 | 0.0377574 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0370121 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0366968 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0354904 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0349393 |
| SET | SET nuclear proto-oncogene | 0.0343854 |
| TPR | translocated promoter region, nuclear basket protein | 0.0340115 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.033548 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0332321 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0330769 |
| RPL26 | ribosomal protein L26 | 0.0330075 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0325494 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0324319 |
| PCBP2 | poly(rC) binding protein 2 | 0.0315577 |
| PLK2 | polo-like kinase 2 | 0.0315476 |
| CANX | calnexin | 0.0315237 |
| SPAG9 | sperm associated antigen 9 | 0.0314404 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.031327 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0312286 |
| RPL4 | ribosomal protein L4 | 0.0311366 |
| CCNL1 | cyclin L1 | 0.0311267 |
| RPL41 | ribosomal protein L41 | 0.030792 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0301516 |
| MSN | moesin | 0.0296449 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0296311 |
| ZNF292 | zinc finger protein 292 | 0.0295368 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0294009 |
| GOLGA4 | golgin A4 | 0.0293395 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0291869 |
| PODXL | podocalyxin-like | 0.0291163 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0288121 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0286677 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0284887 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0284584 |
| PGK1 | phosphoglycerate kinase 1 | 0.02836 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.028309 |
| MKI67 | marker of proliferation Ki-67 | 0.028046 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.028006 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0275798 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0275204 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0275093 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0272794 |
| RPS2 | ribosomal protein S2 | 0.0267485 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.026597 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.02627 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.026232 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0261699 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0260485 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.025928 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0258298 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0257364 |
| DSCAM | Down syndrome cell adhesion molecule | 0.025377 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0252269 |
| RPS18 | ribosomal protein S18 | 0.0251775 |
| ARRDC3 | arrestin domain containing 3 | 0.0248965 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0246619 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0245045 |
| RPS6 | ribosomal protein S6 | 0.0240792 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0238453 |
| ZNF148 | zinc finger protein 148 | 0.0234654 |
| CBX3 | chromobox homolog 3 | 0.023334 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0232171 |
| CD109 | CD109 molecule | 0.0231459 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.422328 |
| VIM | vimentin | -0.157461 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.152956 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0944909 |
| TXNRD1 | thioredoxin reductase 1 | -0.0851542 |
| TP63 | tumor protein p63 | -0.0840311 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0814078 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0729859 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0603465 |
| SRGN | serglycin | -0.0577131 |
| AHNAK | AHNAK nucleoprotein | -0.0555082 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0534371 |
| RUNX1 | runt-related transcription factor 1 | -0.0489991 |
| ACTG1 | actin gamma 1 | -0.048583 |
| HLA-B | major histocompatibility complex, class I, B | -0.0461726 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0460022 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0457064 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0447892 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0436832 |
| CD44 | CD44 molecule (Indian blood group) | -0.0429964 |
| GNAS | GNAS complex locus | -0.0426367 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0426185 |
| RIGI | RNA sensor RIG-I | -0.0424266 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0410292 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0395352 |
| RAB7A | RAB7A, member RAS oncogene family | -0.038747 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0359272 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0346847 |
| EHBP1 | EH domain binding protein 1 | -0.034101 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0338142 |
| HMGA1 | high mobility group AT-hook 1 | -0.0332426 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0326362 |
| RPS24 | ribosomal protein S24 | -0.0325504 |
| EGR1 | early growth response 1 | -0.031733 |
| EMP1 | epithelial membrane protein 1 | -0.0316118 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0315674 |
| RPS15 | ribosomal protein S15 | -0.0307543 |
| SP100 | SP100 nuclear antigen | -0.0306735 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0305132 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0296822 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0296332 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0295122 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0277951 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0262839 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0259958 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0259214 |
| FBXO11 | F-box protein 11 | -0.0258663 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0256648 |
| RPL36A | ribosomal protein L36a | -0.0253427 |
| S100A10 | S100 calcium binding protein A10 | -0.0250859 |
| RPL28 | ribosomal protein L28 | -0.0247677 |
| CAVIN1 | caveolae associated protein 1 | -0.0247455 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0246898 |
| ANXA2 | annexin A2 | -0.0244821 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0239717 |
| PLSCR1 | phospholipid scramblase 1 | -0.0237959 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0236987 |
| CMIP | c-Maf inducing protein | -0.0236967 |
| EPHA4 | EPH receptor A4 | -0.0234463 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0234017 |
| NPR2 | natriuretic peptide receptor 2 | -0.0227227 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0226139 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0226086 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0225339 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.022533 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0224169 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.022319 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0221844 |
| CADM2 | cell adhesion molecule 2 | -0.0217517 |
| BMERB1 | bMERB domain containing 1 | -0.0217112 |
| PMP22 | peripheral myelin protein 22 | -0.0217022 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0216867 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0212885 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0212854 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.020591 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0202945 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 | -0.0197731 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0197712 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.01941 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0193857 |
| TNS3 | tensin 3 | -0.019184 |
| RPL38 | ribosomal protein L38 | -0.0191271 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0189859 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0189819 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0189796 |
| RGS4 | regulator of G-protein signaling 4 | -0.0187946 |
| INTS6 | integrator complex subunit 6 | -0.0187867 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0185882 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.018387 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0180451 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0180273 |
| CCNI | cyclin I | -0.0180221 |
| NF1 | neurofibromin 1 | -0.0179543 |
| TAOK1 | TAO kinase 1 | -0.0178382 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0176991 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.017502 |
| UBE3C | ubiquitin protein ligase E3C | -0.0174403 |
| ZFR | zinc finger RNA binding protein | -0.0173593 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0173405 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0172014 |
