| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mozavaptan_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0765558 |
| PKM | pyruvate kinase, muscle | 0.0681366 |
| ENO1 | enolase 1, (alpha) | 0.0652054 |
| RPS3 | ribosomal protein S3 | 0.0645932 |
| TOP1 | topoisomerase (DNA) I | 0.0634534 |
| TXNRD1 | thioredoxin reductase 1 | 0.0557829 |
| MKI67 | marker of proliferation Ki-67 | 0.0480373 |
| PGK1 | phosphoglycerate kinase 1 | 0.0479336 |
| RPL4 | ribosomal protein L4 | 0.0477881 |
| LAMB3 | laminin, beta 3 | 0.0440174 |
| ASPH | aspartate beta-hydroxylase | 0.0431837 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0426868 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.04254 |
| RPL41 | ribosomal protein L41 | 0.042051 |
| NGLY1 | N-glycanase 1 | 0.0405559 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0393429 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0390692 |
| LAMC2 | laminin, gamma 2 | 0.0389304 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0381538 |
| ZNF292 | zinc finger protein 292 | 0.0377632 |
| SLTM | SAFB-like, transcription modulator | 0.036584 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.034814 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0346038 |
| NUP58 | nucleoporin 58 | 0.0344935 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.033585 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0331566 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0327762 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0324392 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0323365 |
| ARRDC3 | arrestin domain containing 3 | 0.0321837 |
| ECT2 | epithelial cell transforming 2 | 0.0318124 |
| RUNX1 | runt-related transcription factor 1 | 0.029954 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0298948 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.029314 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0291157 |
| CANX | calnexin | 0.0289336 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0284048 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0276797 |
| TES | testin LIM domain protein | 0.027332 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0272622 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0271322 |
| HYOU1 | hypoxia up-regulated 1 | 0.0268998 |
| DSPP | dentin sialophosphoprotein | 0.0265456 |
| RPL37A | ribosomal protein L37a | 0.0264241 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0262345 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0261694 |
| YEATS2 | YEATS domain containing 2 | 0.0260437 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0258403 |
| NCKAP1 | NCK-associated protein 1 | 0.0250029 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.024947 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0247794 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0245856 |
| CALR | calreticulin | 0.0238782 |
| MATR3 | matrin 3 | 0.0237816 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0235853 |
| TPD52 | tumor protein D52 | 0.0235476 |
| APP | amyloid beta (A4) precursor protein | 0.0234421 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0231811 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0229785 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0229602 |
| RPS2 | ribosomal protein S2 | 0.0224696 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0223207 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0221983 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0221306 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0218462 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0215177 |
| RPL12 | ribosomal protein L12 | 0.0213397 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.021187 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.0208596 |
| CENPF | centromere protein F, 350/400kDa | 0.0207699 |
| PAPOLA | poly(A) polymerase alpha | 0.0204637 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0202272 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0201444 |
| CDC73 | cell division cycle 73 | 0.0200261 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0199865 |
| SLK | STE20-like kinase | 0.0199809 |
| YTHDC1 | YTH domain containing 1 | 0.0199509 |
| RPL3 | ribosomal protein L3 | 0.0199068 |
| RPL26 | ribosomal protein L26 | 0.0198393 |
| KLC1 | kinesin light chain 1 | 0.0196566 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0196463 |
| LMO7 | LIM domain 7 | 0.0195073 |
| RPS12 | ribosomal protein S12 | 0.0193695 |
| RASA2 | RAS p21 protein activator 2 | 0.0192782 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0189238 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.018651 |
| LAMA4 | laminin, alpha 4 | 0.0186475 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0186117 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.0182451 |
| RPL34 | ribosomal protein L34 | 0.0178725 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0178399 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.0177731 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0177444 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0175504 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0174595 |
| SERINC1 | serine incorporator 1 | 0.0173462 |
| RPN1 | ribophorin I | 0.0172475 |
| DTNA | dystrobrevin, alpha | 0.0172163 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0171732 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0171099 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.669644 |
| NDRG1 | N-myc downstream regulated 1 | -0.189762 |
| EGFR | epidermal growth factor receptor | -0.127935 |
| EGR1 | early growth response 1 | -0.102068 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0917265 |
| S100A10 | S100 calcium binding protein A10 | -0.0840686 |
| ACTG1 | actin gamma 1 | -0.0728636 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0647394 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0643054 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0639567 |
| INTS6 | integrator complex subunit 6 | -0.0617673 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0605002 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0597419 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.057376 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0570091 |
| STC1 | stanniocalcin 1 | -0.0494399 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.048534 |
| PTMA | prothymosin, alpha | -0.0481839 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0461581 |
| NABP1 | nucleic acid binding protein 1 | -0.0445592 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.043152 |
| RPS25 | ribosomal protein S25 | -0.0424576 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0415841 |
| CST3 | cystatin C | -0.0408988 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0401528 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0401214 |
| WASF2 | WAS protein family, member 2 | -0.0394762 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.038567 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0384296 |
| TMSB10 | thymosin beta 10 | -0.0374565 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0373002 |
| GNAS | GNAS complex locus | -0.0367228 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0343397 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0333483 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0333244 |
| IER3 | immediate early response 3 | -0.0330137 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0320438 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0316153 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0315393 |
| MCL1 | myeloid cell leukemia 1 | -0.0307366 |
| PDE8A | phosphodiesterase 8A | -0.0305582 |
| HMGA1 | high mobility group AT-hook 1 | -0.0303591 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0303223 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0300803 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.029853 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0294363 |
| HLA-B | major histocompatibility complex, class I, B | -0.0280393 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0275935 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0275119 |
| MYO1E | myosin IE | -0.0273947 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0273339 |
| TMEM165 | transmembrane protein 165 | -0.0271848 |
| ARF4 | ADP-ribosylation factor 4 | -0.0270503 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0269619 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0267143 |
| CSTB | cystatin B (stefin B) | -0.0262301 |
| CDCP1 | CUB domain containing protein 1 | -0.0261847 |
| RAB10 | RAB10, member RAS oncogene family | -0.0255123 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0253663 |
| UBC | ubiquitin C | -0.0245674 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0243262 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0241566 |
| AGR2 | anterior gradient 2 | -0.0241226 |
| FOXP1 | forkhead box P1 | -0.0239577 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0239077 |
| CAV2 | caveolin 2 | -0.0236346 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.023516 |
| CCND1 | cyclin D1 | -0.0234626 |
| FUS | FUS RNA binding protein | -0.0232651 |
| IRF1 | interferon regulatory factor 1 | -0.0232556 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0232341 |
| FNDC3B | fibronectin type III domain containing 3B | -0.023171 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0229605 |
| CCNI | cyclin I | -0.0228116 |
| CPE | carboxypeptidase E | -0.0227621 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.02275 |
| NUMB | numb homolog (Drosophila) | -0.0224506 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0222208 |
| CUX1 | cut-like homeobox 1 | -0.0221843 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0218893 |
| VCL | vinculin | -0.0217778 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0217616 |
| AHNAK | AHNAK nucleoprotein | -0.0213941 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.021385 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0212695 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0211346 |
| HM13 | histocompatibility (minor) 13 | -0.0209004 |
| RPS23 | ribosomal protein S23 | -0.0208345 |
| POTEF | POTE ankyrin domain family, member F | -0.0207801 |
| CSNK1E | casein kinase 1, epsilon | -0.0205805 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0205187 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0205001 |
| BRD2 | bromodomain containing 2 | -0.0203802 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0202823 |
| BBX | bobby sox homolog (Drosophila) | -0.0202438 |
| BPTF | bromodomain PHD finger transcription factor | -0.0200319 |
| PHF21A | PHD finger protein 21A | -0.0199844 |
| CD99 | CD99 molecule | -0.0199089 |
| JMJD1C | jumonji domain containing 1C | -0.0198324 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0198098 |
