| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mozavaptan_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.166892 |
| GRB10 | growth factor receptor-bound protein 10 | 0.165046 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.149154 |
| FAM13A | family with sequence similarity 13, member A | 0.142853 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.123883 |
| ENO1 | enolase 1, (alpha) | 0.10651 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0995345 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.09041 |
| NGLY1 | N-glycanase 1 | 0.0899952 |
| PKM | pyruvate kinase, muscle | 0.0876296 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0853395 |
| ATP13A3 | ATPase type 13A3 | 0.0852833 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.082825 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0824618 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0817886 |
| LOX | lysyl oxidase | 0.0815682 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0802572 |
| MEF2A | myocyte enhancer factor 2A | 0.0779875 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.076732 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0761288 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0738805 |
| FN1 | fibronectin 1 | 0.0733562 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0729296 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0726323 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0710731 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0699388 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0696179 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0665202 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.066025 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0660088 |
| CALR | calreticulin | 0.0653267 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0632171 |
| SMAD3 | SMAD family member 3 | 0.0629032 |
| PRELID2 | PRELI domain containing 2 | 0.0619202 |
| RPL4 | ribosomal protein L4 | 0.0614566 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0607465 |
| USP3 | ubiquitin specific peptidase 3 | 0.0604539 |
| CDH13 | cadherin 13 | 0.060383 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0591325 |
| APP | amyloid beta (A4) precursor protein | 0.0572213 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0561924 |
| RIOK3 | RIO kinase 3 | 0.0553156 |
| NAV2 | neuron navigator 2 | 0.0540035 |
| CANX | calnexin | 0.0531585 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0511151 |
| TMSB4X | thymosin beta 4, X-linked | 0.050968 |
| LDHA | lactate dehydrogenase A | 0.0507637 |
| SPAG9 | sperm associated antigen 9 | 0.0502202 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0501166 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0491757 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0489358 |
| GOLGA4 | golgin A4 | 0.0487829 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0479374 |
| HELZ | helicase with zinc finger | 0.0467483 |
| FMNL2 | formin-like 2 | 0.0464653 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0457855 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0455163 |
| MYO1B | myosin IB | 0.0454835 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.045099 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0434846 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0427802 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0424172 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0423999 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0415018 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0413564 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0406459 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0400018 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0397075 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0394683 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0394274 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0393155 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0393073 |
| COPA | coatomer protein complex, subunit alpha | 0.0391648 |
| AFF4 | AF4/FMR2 family, member 4 | 0.039081 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0390684 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0387278 |
| FLNB | filamin B, beta | 0.0384056 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0381479 |
| ADM | adrenomedullin | 0.0380867 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0380673 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0378863 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0376655 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0372826 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0371816 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0367991 |
| WDR45B | WD repeat domain 45B | 0.036569 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0364088 |
| INSIG2 | insulin induced gene 2 | 0.0362573 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 0.0356585 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0356152 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0349887 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0348325 |
| CDC73 | cell division cycle 73 | 0.0347002 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0345362 |
| PGK1 | phosphoglycerate kinase 1 | 0.0345073 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0344697 |
| FAM20C | family with sequence similarity 20, member C | 0.0337292 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.033553 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0335454 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0331197 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.240834 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.125621 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0928215 |
| OSMR | oncostatin M receptor | -0.0668472 |
| GLCCI1 | glucocorticoid induced 1 | -0.0661472 |
| MT2A | metallothionein 2A | -0.0572001 |
| NRP1 | neuropilin 1 | -0.0559651 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0554107 |
| CD44 | CD44 molecule (Indian blood group) | -0.0547435 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0508305 |
| EGR1 | early growth response 1 | -0.050461 |
| VIM | vimentin | -0.0490874 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0434395 |
| NCOA7 | nuclear receptor coactivator 7 | -0.041098 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0408356 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0406646 |
| HMGA1 | high mobility group AT-hook 1 | -0.0384252 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0377125 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.037582 |
| FRMD4A | FERM domain containing 4A | -0.0355678 |
| NDRG1 | N-myc downstream regulated 1 | -0.0338511 |
| BPTF | bromodomain PHD finger transcription factor | -0.0330041 |
| KYNU | kynureninase | -0.0327811 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0326116 |
| NABP1 | nucleic acid binding protein 1 | -0.0323396 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0323117 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0315944 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0312802 |
| SYAP1 | synapse associated protein 1 | -0.0312549 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0304588 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0297811 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0294713 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0294054 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0288107 |
| TGM2 | transglutaminase 2 | -0.0278999 |
| TMEM165 | transmembrane protein 165 | -0.0273667 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0271498 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0269293 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0268755 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0267282 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0266132 |
| VCL | vinculin | -0.0263801 |
| BRD2 | bromodomain containing 2 | -0.0262086 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.026156 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0252523 |
| HM13 | histocompatibility (minor) 13 | -0.0246939 |
| FNBP1 | formin binding protein 1 | -0.0246687 |
| ZNF609 | zinc finger protein 609 | -0.0246445 |
| ETV6 | ets variant 6 | -0.0244557 |
| MX2 | MX dynamin-like GTPase 2 | -0.0244414 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.02437 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0241309 |
| KSR1 | kinase suppressor of ras 1 | -0.023951 |
| B2M | beta-2-microglobulin | -0.0233408 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0233253 |
| ATF7 | activating transcription factor 7 | -0.023252 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0231737 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0230542 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0229368 |
| NTN4 | netrin 4 | -0.0226166 |
| RPL28 | ribosomal protein L28 | -0.021887 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0215702 |
| ZFP91 | ZFP91 zinc finger protein | -0.021438 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0209536 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0209344 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0209023 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0207291 |
| STC1 | stanniocalcin 1 | -0.0207169 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0204953 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0202206 |
| ANKRD28 | ankyrin repeat domain 28 | -0.020043 |
| RPS21 | ribosomal protein S21 | -0.0200243 |
| S100A10 | S100 calcium binding protein A10 | -0.0200115 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0200097 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0199882 |
| SELENOF | selenoprotein F | -0.0198861 |
| RAD51B | RAD51 paralog B | -0.0198476 |
| ARF4 | ADP-ribosylation factor 4 | -0.0196796 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0194451 |
| COPZ1 | coatomer protein complex, subunit zeta 1 | -0.019441 |
| RNF24 | ring finger protein 24 | -0.0193484 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0192653 |
| STK38L | serine/threonine kinase 38 like | -0.0192509 |
| TNNC1 | troponin C type 1 (slow) | -0.019165 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0188477 |
| EHBP1 | EH domain binding protein 1 | -0.0186547 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0185199 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0185029 |
| DUSP5 | dual specificity phosphatase 5 | -0.0183892 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0183077 |
| MX1 | MX dynamin-like GTPase 1 | -0.0180699 |
| ECE1 | endothelin converting enzyme 1 | -0.0180398 |
| IL1R1 | interleukin 1 receptor, type I | -0.0179886 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0178757 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0178036 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0177832 |
| KIAA1217 | KIAA1217 | -0.0177394 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0176825 |
| TMEM263 | transmembrane protein 263 | -0.0176194 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0175382 |
