| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mozavaptan_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPC6 | glypican 6 | 0.201055 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.109738 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0979482 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0978644 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0966594 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0895433 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0864262 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0852832 |
| ATP13A3 | ATPase type 13A3 | 0.0840155 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0805855 |
| NAV2 | neuron navigator 2 | 0.0763497 |
| SEPTIN9 | septin 9 | 0.0729087 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0700936 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0691705 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0690563 |
| FN1 | fibronectin 1 | 0.0674233 |
| FMNL2 | formin-like 2 | 0.0664375 |
| UVRAG | UV radiation resistance associated | 0.0652181 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0635622 |
| IST1 | increased sodium tolerance 1 homolog (yeast) | 0.0632377 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0609277 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0597742 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.05883 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) | 0.0582392 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0582208 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.0564421 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0556084 |
| CTBP2 | C-terminal binding protein 2 | 0.0550887 |
| SRFBP1 | serum response factor binding protein 1 | 0.054934 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0549123 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0546229 |
| VGLL4 | vestigial-like family member 4 | 0.0539815 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0534466 |
| ZNF638 | zinc finger protein 638 | 0.0529433 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0526809 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0520242 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0517781 |
| KLC1 | kinesin light chain 1 | 0.0495513 |
| TAOK1 | TAO kinase 1 | 0.0482252 |
| FAT1 | FAT atypical cadherin 1 | 0.047356 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0466681 |
| OXR1 | oxidation resistance 1 | 0.0463404 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0457986 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0453644 |
| WWOX | WW domain containing oxidoreductase | 0.0451404 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0446237 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0439282 |
| VGF | VGF nerve growth factor inducible | 0.0435578 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0434412 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0428679 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0415771 |
| NCKAP1 | NCK-associated protein 1 | 0.0413759 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0413738 |
| YTHDC1 | YTH domain containing 1 | 0.0409479 |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.0408353 |
| NHSL1 | NHS-like 1 | 0.0407305 |
| RPS24 | ribosomal protein S24 | 0.0404417 |
| PRKCA | protein kinase C, alpha | 0.0393528 |
| PTK2 | protein tyrosine kinase 2 | 0.0392687 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0385399 |
| ASPH | aspartate beta-hydroxylase | 0.0383563 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0378966 |
| NEMF | nuclear export mediator factor | 0.0378691 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0376428 |
| HMGA2 | high mobility group AT-hook 2 | 0.0375982 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0374495 |
| RPL35A | ribosomal protein L35a | 0.0373541 |
| RPL15 | ribosomal protein L15 | 0.037275 |
| USP36 | ubiquitin specific peptidase 36 | 0.0368881 |
| NUP58 | nucleoporin 58 | 0.0367654 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0366248 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0362299 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.035834 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0358136 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0357165 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0355608 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 0.0355012 |
| YEATS2 | YEATS domain containing 2 | 0.0354821 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.0350259 |
| CLTC | clathrin, heavy chain (Hc) | 0.0350165 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.034891 |
| COPA | coatomer protein complex, subunit alpha | 0.0347065 |
| MYOF | myoferlin | 0.0342006 |
| CALR | calreticulin | 0.0340432 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0338329 |
| ANXA11 | annexin A11 | 0.0337926 |
| ZNF644 | zinc finger protein 644 | 0.0337637 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0337286 |
| MAPK6 | mitogen-activated protein kinase 6 | 0.0334881 |
| MATR3 | matrin 3 | 0.0334844 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0334518 |
| NGLY1 | N-glycanase 1 | 0.033267 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0332645 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0332318 |
| CD2AP | CD2-associated protein | 0.0331988 |
| RPS8 | ribosomal protein S8 | 0.0331329 |
| PGK1 | phosphoglycerate kinase 1 | 0.0330436 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0327983 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0324638 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0323362 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.203393 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.199732 |
| MYO1E | myosin IE | -0.136312 |
| FNDC3B | fibronectin type III domain containing 3B | -0.114579 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.114415 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112207 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109514 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109259 |
| LAMB3 | laminin, beta 3 | -0.106157 |
| IGF2 | insulin-like growth factor 2 | -0.102098 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0917636 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0850666 |
| KYNU | kynureninase | -0.0804849 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0770413 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.074911 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0745572 |
| STC1 | stanniocalcin 1 | -0.074097 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0725807 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0717201 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0700085 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0699287 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0640173 |
| MXD1 | MAX dimerization protein 1 | -0.063815 |
| LDHA | lactate dehydrogenase A | -0.0624568 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0619897 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0617758 |
| MCTP2 | multiple C2 domains, transmembrane 2 | -0.060393 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0595605 |
| KRT17 | keratin 17, type I | -0.0595143 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0594152 |
| MCL1 | myeloid cell leukemia 1 | -0.0592396 |
| FMN1 | formin 1 | -0.0590069 |
| ANXA1 | annexin A1 | -0.0587028 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.058282 |
| NPTN | neuroplastin | -0.0582678 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0581222 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0580783 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0579777 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0564744 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0561656 |
| TJP1 | tight junction protein 1 | -0.055967 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.055094 |
| ACTG1 | actin gamma 1 | -0.0540082 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0529072 |
| ANO6 | anoctamin 6 | -0.0523965 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0521036 |
| B2M | beta-2-microglobulin | -0.0520025 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0518854 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0517923 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0504241 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0504068 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.049737 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0490354 |
| HLA-B | major histocompatibility complex, class I, B | -0.0483516 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0478389 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0474354 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0446696 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0441232 |
| RIGI | RNA sensor RIG-I | -0.0436459 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0430799 |
| RPS3 | ribosomal protein S3 | -0.0430787 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0429552 |
| ATP11B | ATPase, class VI, type 11B | -0.0421668 |
| ATOSA | atos homolog A | -0.0420733 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.041899 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0417021 |
| RBM39 | RNA binding motif protein 39 | -0.0415578 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0415277 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0413116 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.040916 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0408471 |
| PARD3 | par-3 family cell polarity regulator | -0.0405296 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0401296 |
| MEF2A | myocyte enhancer factor 2A | -0.0400304 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0400252 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0387511 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0383672 |
| SEPTIN7 | septin 7 | -0.0382833 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0382035 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0380223 |
| TMSB10 | thymosin beta 10 | -0.037887 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0378525 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0377035 |
| RNF145 | ring finger protein 145 | -0.0370417 |
| JMJD1C | jumonji domain containing 1C | -0.0365165 |
| CCNI | cyclin I | -0.0362026 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0357478 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0357395 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0349913 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0346025 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0343835 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0343665 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0333057 |
| LMO7 | LIM domain 7 | -0.0327696 |
| RNF24 | ring finger protein 24 | -0.0321639 |
| FLNB | filamin B, beta | -0.0317135 |
| S100A10 | S100 calcium binding protein A10 | -0.0312521 |
| YAP1 | Yes-associated protein 1 | -0.0309823 |
| WASF2 | WAS protein family, member 2 | -0.0306363 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0305718 |
