| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.148248 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.123657 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0992249 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0744102 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0668334 |
| TPM3 | tropomyosin 3 | 0.0625241 |
| XPO1 | exportin 1 | 0.0555028 |
| PHIP | pleckstrin homology domain interacting protein | 0.0530912 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0514181 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0505164 |
| RTN4 | reticulon 4 | 0.0454014 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0452497 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0441179 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0416383 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0408922 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0404226 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0390474 |
| PCBP2 | poly(rC) binding protein 2 | 0.0375969 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0356282 |
| CEP192 | centrosomal protein 192kDa | 0.0352991 |
| OGA | O-GlcNAcase | 0.034921 |
| CENPF | centromere protein F, 350/400kDa | 0.0345118 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0343331 |
| MKI67 | marker of proliferation Ki-67 | 0.0341046 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0338948 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0336835 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.033237 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0331979 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0327908 |
| BBX | bobby sox homolog (Drosophila) | 0.0325836 |
| YBX1 | Y box binding protein 1 | 0.0325247 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.029821 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0297911 |
| ANKRD36 | ankyrin repeat domain 36 | 0.029415 |
| NCKAP1 | NCK-associated protein 1 | 0.0289966 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.028865 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0284216 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0284048 |
| NUP58 | nucleoporin 58 | 0.0281932 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.028094 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0274471 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0274356 |
| PCNX1 | pecanex 1 | 0.0272921 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0272642 |
| ZNF292 | zinc finger protein 292 | 0.027235 |
| NUP153 | nucleoporin 153kDa | 0.0271292 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0269598 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0269396 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0268809 |
| PLCB4 | phospholipase C, beta 4 | 0.026805 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0267009 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.026348 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0262874 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0262623 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0261644 |
| RPL3 | ribosomal protein L3 | 0.0260735 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0258675 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0258482 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0255955 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0254938 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0254387 |
| PCM1 | pericentriolar material 1 | 0.0253166 |
| PKM | pyruvate kinase, muscle | 0.0250708 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0248243 |
| SET | SET nuclear proto-oncogene | 0.0246975 |
| ENO1 | enolase 1, (alpha) | 0.0242681 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0242553 |
| KIF5B | kinesin family member 5B | 0.0242501 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0242117 |
| MIS18BP1 | MIS18 binding protein 1 | 0.024067 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0239479 |
| IPO7 | importin 7 | 0.0239104 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0235446 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0235202 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0233975 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0233529 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0232685 |
| PNN | pinin, desmosome associated protein | 0.0232647 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0231825 |
| SRPK1 | SRSF protein kinase 1 | 0.0231688 |
| LDHB | lactate dehydrogenase B | 0.0231179 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0230636 |
| MELK | maternal embryonic leucine zipper kinase | 0.0225935 |
| COG5 | component of oligomeric golgi complex 5 | 0.0224098 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0221539 |
| TMPO | thymopoietin | 0.0220477 |
| THOC1 | THO complex 1 | 0.0219832 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0219567 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0218455 |
| RPL41 | ribosomal protein L41 | 0.0217891 |
| SPAG9 | sperm associated antigen 9 | 0.0214731 |
| AFF4 | AF4/FMR2 family, member 4 | 0.021304 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0211883 |
| PALS1 | protein associated with LIN7 1, MAGUK p55 family member | 0.0206656 |
| MATR3 | matrin 3 | 0.0206623 |
| OLA1 | Obg-like ATPase 1 | 0.0205581 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0204156 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0204088 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0203634 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0202886 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.294846 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.186229 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.177764 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.119989 |
| OSMR | oncostatin M receptor | -0.104828 |
| MCL1 | myeloid cell leukemia 1 | -0.0994542 |
| YBX3 | Y box binding protein 3 | -0.098253 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0962356 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0858229 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0842421 |
| VCL | vinculin | -0.08309 |
| TMSB10 | thymosin beta 10 | -0.0815726 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0808816 |
| PDE10A | phosphodiesterase 10A | -0.0801538 |
| HMGA2 | high mobility group AT-hook 2 | -0.0742747 |
| AEBP2 | AE binding protein 2 | -0.0662642 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0645423 |
| HLA-B | major histocompatibility complex, class I, B | -0.0639399 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0639301 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0633978 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0631821 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.062283 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0598757 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.059824 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0596063 |
| INTS6 | integrator complex subunit 6 | -0.058153 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0569829 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0552206 |
| RYR3 | ryanodine receptor 3 | -0.0535828 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0526564 |
| DOCK5 | dedicator of cytokinesis 5 | -0.05015 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0493267 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0463844 |
| ATXN1 | ataxin 1 | -0.0461561 |
| EGR1 | early growth response 1 | -0.0453513 |
| FMNL2 | formin-like 2 | -0.04508 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0448515 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0444253 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0442733 |
| RNF213 | ring finger protein 213 | -0.0434266 |
| CUX1 | cut-like homeobox 1 | -0.042298 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0421266 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0418847 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0418485 |
| RPL35A | ribosomal protein L35a | -0.0400175 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0399588 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0398229 |
| PTMA | prothymosin, alpha | -0.0392137 |
| ATG7 | autophagy related 7 | -0.0391757 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0390264 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0385246 |
| NABP1 | nucleic acid binding protein 1 | -0.0384224 |
| RAD51B | RAD51 paralog B | -0.0381399 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0377265 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0375626 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0370611 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0370207 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0366628 |
| ACTG1 | actin gamma 1 | -0.0366122 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0366022 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0360669 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0360037 |
| STC1 | stanniocalcin 1 | -0.035955 |
| WWOX | WW domain containing oxidoreductase | -0.0352016 |
| NF1 | neurofibromin 1 | -0.0350232 |
| MT2A | metallothionein 2A | -0.0349937 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0348926 |
| EHBP1 | EH domain binding protein 1 | -0.0334847 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0331257 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0323094 |
| EGFR | epidermal growth factor receptor | -0.0322187 |
| TPM4 | tropomyosin 4 | -0.0320734 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0318886 |
| FBXO11 | F-box protein 11 | -0.0310962 |
| RBM39 | RNA binding motif protein 39 | -0.0310813 |
| DENND5B | DENN/MADD domain containing 5B | -0.0309643 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0309611 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0308756 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0306724 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0305884 |
| GNAS | GNAS complex locus | -0.0305857 |
| R3HDM2 | R3H domain containing 2 | -0.0304253 |
| RPL37 | ribosomal protein L37 | -0.0304124 |
| AHNAK | AHNAK nucleoprotein | -0.0299906 |
| RPS8 | ribosomal protein S8 | -0.0298667 |
| NEK10 | NIMA-related kinase 10 | -0.0295998 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0295474 |
| LOXL2 | lysyl oxidase-like 2 | -0.0287134 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0287022 |
| IER3 | immediate early response 3 | -0.0283993 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0278138 |
| SVIL | supervillin | -0.0278055 |
| RPL31 | ribosomal protein L31 | -0.0276356 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0272787 |
| PCNX4 | pecanex 4 | -0.0272152 |
| RSU1 | Ras suppressor protein 1 | -0.027168 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0268965 |
| ITSN1 | intersectin 1 (SH3 domain protein) | -0.0266927 |
| VIM | vimentin | -0.0265994 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0261932 |
