| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.171705 |
| IGF2 | insulin-like growth factor 2 | 0.170617 |
| EFNA5 | ephrin-A5 | 0.10788 |
| SEPTIN9 | septin 9 | 0.103309 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0938422 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0923174 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.088661 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0882493 |
| FN1 | fibronectin 1 | 0.0844347 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0805253 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0796508 |
| TPM3 | tropomyosin 3 | 0.0779223 |
| FTL | ferritin, light polypeptide | 0.0759158 |
| ZNF292 | zinc finger protein 292 | 0.073239 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0719039 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0693267 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0686696 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0684774 |
| FAM13A | family with sequence similarity 13, member A | 0.0684724 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0677582 |
| PRELID2 | PRELI domain containing 2 | 0.0667274 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0667047 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0665819 |
| RORA | RAR-related orphan receptor A | 0.0641573 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0633951 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0609231 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0585874 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0585296 |
| TOP1 | topoisomerase (DNA) I | 0.056779 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0567122 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.056282 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0542121 |
| SYT1 | synaptotagmin I | 0.053874 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0532714 |
| OGA | O-GlcNAcase | 0.0529904 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0526256 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0525157 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0520345 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0496017 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.048997 |
| PREPL | prolyl endopeptidase-like | 0.0488109 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0478493 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0474657 |
| ENO1 | enolase 1, (alpha) | 0.0470969 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.045407 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0452127 |
| HELZ | helicase with zinc finger | 0.0434456 |
| BRD4 | bromodomain containing 4 | 0.0434348 |
| USP25 | ubiquitin specific peptidase 25 | 0.0424181 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0423444 |
| GOLGB1 | golgin B1 | 0.0415422 |
| B2M | beta-2-microglobulin | 0.0401631 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0399227 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0394286 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0392231 |
| PTMA | prothymosin, alpha | 0.0391076 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0389758 |
| RSF1 | remodeling and spacing factor 1 | 0.0388176 |
| USP34 | ubiquitin specific peptidase 34 | 0.0363139 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0350976 |
| PARD3 | par-3 family cell polarity regulator | 0.0350429 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0349841 |
| GPHN | gephyrin | 0.0349377 |
| XPO1 | exportin 1 | 0.0346042 |
| RPLP1 | ribosomal protein, large, P1 | 0.03348 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0320553 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0318894 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0310307 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0310089 |
| RPS3 | ribosomal protein S3 | 0.0309792 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0309121 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0307495 |
| KIF5B | kinesin family member 5B | 0.0306286 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0300535 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0294833 |
| PKM | pyruvate kinase, muscle | 0.028554 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0284268 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0276601 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0265796 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0262861 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0260838 |
| CCDC88A | coiled-coil domain containing 88A | 0.0260565 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0258251 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0254632 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0253104 |
| RPS12 | ribosomal protein S12 | 0.0252104 |
| RBM26 | RNA binding motif protein 26 | 0.0251131 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0238617 |
| PTK2 | protein tyrosine kinase 2 | 0.0236437 |
| RPL11 | ribosomal protein L11 | 0.0231818 |
| RLF | rearranged L-myc fusion | 0.0223635 |
| CANX | calnexin | 0.0222632 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0222166 |
| FNIP1 | folliculin interacting protein 1 | 0.0214314 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0210811 |
| MEF2A | myocyte enhancer factor 2A | 0.020985 |
| RIOK3 | RIO kinase 3 | 0.0209366 |
| NAV2 | neuron navigator 2 | 0.020752 |
| NBAS | neuroblastoma amplified sequence | 0.0207327 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0201728 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.169454 |
| GPC6 | glypican 6 | -0.128947 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.115685 |
| TENM3 | teneurin transmembrane protein 3 | -0.110028 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.105416 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0961862 |
| CD2AP | CD2-associated protein | -0.0949922 |
| ACTG1 | actin gamma 1 | -0.0946762 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0928079 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.091568 |
| VMP1 | vacuole membrane protein 1 | -0.0898406 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0849498 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0791427 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0788806 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0770268 |
| VCL | vinculin | -0.070557 |
| FLNB | filamin B, beta | -0.0702143 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.068684 |
| RPS8 | ribosomal protein S8 | -0.0675569 |
| VIM | vimentin | -0.0671394 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0651052 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0643911 |
| MAP4 | microtubule-associated protein 4 | -0.0618703 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.061776 |
| QKI | QKI, KH domain containing, RNA binding | -0.0616938 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0614128 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0601326 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0570423 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0543898 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0543861 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0541835 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0534813 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0525968 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0524555 |
| NDRG1 | N-myc downstream regulated 1 | -0.0519111 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0507699 |
| RTN4 | reticulon 4 | -0.0504623 |
| JMJD1C | jumonji domain containing 1C | -0.0498081 |
| RPL26 | ribosomal protein L26 | -0.0492395 |
| GNAS | GNAS complex locus | -0.049111 |
| RPS27A | ribosomal protein S27a | -0.048414 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0474293 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.04679 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0466195 |
| PGK1 | phosphoglycerate kinase 1 | -0.0463964 |
| PEG10 | paternally expressed 10 | -0.0453291 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0439295 |
| DST | dystonin | -0.0436486 |
| RPL34 | ribosomal protein L34 | -0.0435457 |
| RBM25 | RNA binding motif protein 25 | -0.0424796 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.040929 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0401647 |
| RPLP0 | ribosomal protein, large, P0 | -0.0395653 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0394605 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0385964 |
| GOLGA4 | golgin A4 | -0.0379096 |
| STK4 | serine/threonine kinase 4 | -0.0375523 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0364861 |
| RPL23 | ribosomal protein L23 | -0.036214 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0360302 |
| RPS6 | ribosomal protein S6 | -0.035741 |
| ZNF148 | zinc finger protein 148 | -0.0357102 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0342293 |
| AHNAK | AHNAK nucleoprotein | -0.033795 |
| STC1 | stanniocalcin 1 | -0.0336665 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0323234 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0321831 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0294391 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0288705 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0286914 |
| FRMD5 | FERM domain containing 5 | -0.0282029 |
| RPL35A | ribosomal protein L35a | -0.0277007 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0270658 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0262325 |
| RPS23 | ribosomal protein S23 | -0.0261118 |
| RRBP1 | ribosome binding protein 1 | -0.0258773 |
| LAMA4 | laminin, alpha 4 | -0.0250758 |
| MSN | moesin | -0.0235286 |
| RPS16 | ribosomal protein S16 | -0.0233791 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0230821 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0229143 |
| EZR | ezrin | -0.0224497 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0216009 |
| LDHA | lactate dehydrogenase A | -0.0211238 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0205057 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0203181 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0194941 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0192548 |
| CD44 | CD44 molecule (Indian blood group) | -0.0186689 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0185693 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0177131 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0164348 |
| PHF21A | PHD finger protein 21A | -0.016349 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0162727 |
| DIAPH2 | diaphanous-related formin 2 | -0.0162219 |
| EGR1 | early growth response 1 | -0.0161752 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0154708 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0150205 |
| SEPTIN7 | septin 7 | -0.0140027 |
| ACTN4 | actinin, alpha 4 | -0.0137838 |
