| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.234172 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.155551 |
| TMSB4X | thymosin beta 4, X-linked | 0.135213 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.122483 |
| RPS3 | ribosomal protein S3 | 0.103433 |
| RPL35A | ribosomal protein L35a | 0.102842 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.101683 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0892618 |
| ENO1 | enolase 1, (alpha) | 0.0865015 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0850484 |
| LDHA | lactate dehydrogenase A | 0.0796018 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0786921 |
| MT2A | metallothionein 2A | 0.0763101 |
| RPL12 | ribosomal protein L12 | 0.0741172 |
| RPL26 | ribosomal protein L26 | 0.0729375 |
| RPS12 | ribosomal protein S12 | 0.0708226 |
| S100A6 | S100 calcium binding protein A6 | 0.069629 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0695083 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0675242 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0672345 |
| EZR | ezrin | 0.0662661 |
| GOLGA4 | golgin A4 | 0.0660728 |
| RPL37A | ribosomal protein L37a | 0.0651575 |
| RPL34 | ribosomal protein L34 | 0.0639913 |
| RACK1 | receptor for activated C kinase 1 | 0.0609966 |
| RPL13A | ribosomal protein L13a | 0.0604726 |
| RPS8 | ribosomal protein S8 | 0.0604663 |
| CALR | calreticulin | 0.0595317 |
| RPL4 | ribosomal protein L4 | 0.0589059 |
| PKM | pyruvate kinase, muscle | 0.0574326 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0551804 |
| RPS19 | ribosomal protein S19 | 0.0540527 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0538706 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0514802 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0501026 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0486695 |
| RPL11 | ribosomal protein L11 | 0.0469808 |
| PGK1 | phosphoglycerate kinase 1 | 0.0465167 |
| RPL9 | ribosomal protein L9 | 0.0462418 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0456569 |
| TXNIP | thioredoxin interacting protein | 0.0455835 |
| FTL | ferritin, light polypeptide | 0.0444372 |
| RPL36 | ribosomal protein L36 | 0.0435246 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0431417 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0424593 |
| YBX1 | Y box binding protein 1 | 0.0422771 |
| RPS27A | ribosomal protein S27a | 0.0418311 |
| ZNF292 | zinc finger protein 292 | 0.040073 |
| TMSB10 | thymosin beta 10 | 0.0391846 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0391165 |
| RPS6 | ribosomal protein S6 | 0.0388254 |
| ECT2 | epithelial cell transforming 2 | 0.0380497 |
| RPL31 | ribosomal protein L31 | 0.0377718 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.037444 |
| CANX | calnexin | 0.0374247 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0372982 |
| RPL18 | ribosomal protein L18 | 0.0369309 |
| ATF4 | activating transcription factor 4 | 0.0366672 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0361224 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0358694 |
| COPA | coatomer protein complex, subunit alpha | 0.0357592 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0354847 |
| RPLP0 | ribosomal protein, large, P0 | 0.0350043 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0348691 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0342767 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0340786 |
| RPLP1 | ribosomal protein, large, P1 | 0.0339612 |
| TPI1 | triosephosphate isomerase 1 | 0.0337351 |
| SSR1 | signal sequence receptor, alpha | 0.0335557 |
| RPL19 | ribosomal protein L19 | 0.0334969 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0329595 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0328787 |
| RPL7 | ribosomal protein L7 | 0.0328197 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0326356 |
| HMGB2 | high mobility group box 2 | 0.032471 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0316865 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0316801 |
| RPL41 | ribosomal protein L41 | 0.0313325 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0309036 |
| TMF1 | TATA element modulatory factor 1 | 0.0289151 |
| PRDX2 | peroxiredoxin 2 | 0.0288686 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0285835 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0282615 |
| RNF145 | ring finger protein 145 | 0.0281879 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0272494 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.026948 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0268473 |
| RPS17 | ribosomal protein S17 | 0.0266758 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0264003 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0263064 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | 0.0262586 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0262487 |
| COG6 | component of oligomeric golgi complex 6 | 0.0262166 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0259563 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0259024 |
| WDR43 | WD repeat domain 43 | 0.025891 |
| PHF3 | PHD finger protein 3 | 0.0258765 |
| RPL5 | ribosomal protein L5 | 0.0258073 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0256767 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0253211 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.125633 |
| AHNAK | AHNAK nucleoprotein | -0.116513 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0978158 |
| VCL | vinculin | -0.0857101 |
| EGFR | epidermal growth factor receptor | -0.085504 |
| FOXP1 | forkhead box P1 | -0.0784508 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0740188 |
| NBEA | neurobeachin | -0.0737024 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0709191 |
| BMP10 | bone morphogenetic protein 10 | -0.0694455 |
| GSE1 | Gse1 coiled-coil protein | -0.0623754 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0581638 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0550247 |
| CCND1 | cyclin D1 | -0.0547995 |
| GLI3 | GLI family zinc finger 3 | -0.0542119 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.050324 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0484138 |
| PARD3 | par-3 family cell polarity regulator | -0.0471683 |
| GLI2 | GLI family zinc finger 2 | -0.0466393 |
| FLNB | filamin B, beta | -0.0440496 |
| BMP2K | BMP2 inducible kinase | -0.0387675 |
| PYGB | phosphorylase, glycogen; brain | -0.0384134 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0383069 |
| CUX1 | cut-like homeobox 1 | -0.0382454 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0380698 |
| USP34 | ubiquitin specific peptidase 34 | -0.0375319 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.036944 |
| TXNRD1 | thioredoxin reductase 1 | -0.0366155 |
| ZNF438 | zinc finger protein 438 | -0.0365935 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0357869 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0355391 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0354629 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0351528 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0342539 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0342019 |
| MYO5C | myosin VC | -0.0339535 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0331138 |
| NPAS2 | neuronal PAS domain protein 2 | -0.033103 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0326208 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0324797 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0316214 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0314333 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | -0.031269 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0312316 |
| EVI5 | ecotropic viral integration site 5 | -0.0307206 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0306519 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0302218 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0300767 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0298698 |
| MACROD2 | MACRO domain containing 2 | -0.0291917 |
| GPHN | gephyrin | -0.0291818 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.029103 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0288147 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0287283 |
| EXOC6B | exocyst complex component 6B | -0.0287271 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0287102 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0284169 |
| NF1 | neurofibromin 1 | -0.0280831 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0274721 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0274306 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0267925 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.026678 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0266282 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0265169 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0264094 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0263346 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.026111 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0261078 |
| SRPK2 | SRSF protein kinase 2 | -0.0254894 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.025239 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0252076 |
| SMYD3 | SET and MYND domain containing 3 | -0.0249015 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.02485 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0244991 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0243857 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0243311 |
| PKP4 | plakophilin 4 | -0.0242439 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0242153 |
| DGKH | diacylglycerol kinase, eta | -0.0241963 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0240773 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0240295 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0237236 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0236303 |
| PDE7B | phosphodiesterase 7B | -0.0233556 |
| ZNF609 | zinc finger protein 609 | -0.0230404 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.022982 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.022981 |
| DARS1 | aspartyl-tRNA synthetase 1 | -0.022729 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | -0.0226977 |
| COMMD10 | COMM domain containing 10 | -0.0226558 |
| OSMR | oncostatin M receptor | -0.0224596 |
| TCF12 | transcription factor 12 | -0.0221001 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.021994 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0217991 |
| METTL15 | methyltransferase like 15 | -0.0217076 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0216078 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0214133 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0211055 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0208774 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | -0.0208149 |