| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Mozavaptan_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.208335 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.181399 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.152033 |
| FN1 | fibronectin 1 | 0.150728 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.111184 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0947246 |
| NAV2 | neuron navigator 2 | 0.0887598 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0876432 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0801684 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0758268 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0722808 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0667564 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0657727 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0632051 |
| CENPF | centromere protein F, 350/400kDa | 0.0616556 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0601802 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0582293 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0558069 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0546127 |
| DST | dystonin | 0.0527647 |
| ANLN | anillin, actin binding protein | 0.0514176 |
| MSN | moesin | 0.0492954 |
| MKI67 | marker of proliferation Ki-67 | 0.0467637 |
| SPAG9 | sperm associated antigen 9 | 0.0432433 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0430695 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0422569 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0409456 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0404323 |
| CCNL1 | cyclin L1 | 0.0395799 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0395797 |
| ENO1 | enolase 1, (alpha) | 0.0394689 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0392347 |
| ZNF292 | zinc finger protein 292 | 0.0390983 |
| ARRDC3 | arrestin domain containing 3 | 0.0386431 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0374984 |
| APP | amyloid beta (A4) precursor protein | 0.0374314 |
| VMP1 | vacuole membrane protein 1 | 0.0373684 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0370442 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0363185 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0359161 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.034926 |
| ATP13A3 | ATPase type 13A3 | 0.0349004 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0345732 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.03301 |
| SERINC1 | serine incorporator 1 | 0.0328414 |
| CD164 | CD164 molecule, sialomucin | 0.0326084 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0318675 |
| SMAD3 | SMAD family member 3 | 0.0307984 |
| RPL4 | ribosomal protein L4 | 0.0304611 |
| AFDN | afadin, adherens junction formation factor | 0.0301623 |
| DENND5A | DENN/MADD domain containing 5A | 0.0301557 |
| EZR | ezrin | 0.0292976 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0291573 |
| SBF2 | SET binding factor 2 | 0.0290837 |
| YBX1 | Y box binding protein 1 | 0.0284077 |
| MX1 | MX dynamin-like GTPase 1 | 0.0282175 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0280766 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.027636 |
| RPS3 | ribosomal protein S3 | 0.0274562 |
| DIAPH3 | diaphanous-related formin 3 | 0.02733 |
| TPM3 | tropomyosin 3 | 0.0271564 |
| KIF4A | kinesin family member 4A | 0.0270935 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0263759 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0257986 |
| CALR | calreticulin | 0.0256736 |
| RPL41 | ribosomal protein L41 | 0.0251191 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0249202 |
| HOMER2 | homer scaffolding protein 2 | 0.0244231 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.023563 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0235208 |
| MXI1 | MAX interactor 1, dimerization protein | 0.023401 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0232209 |
| MYOF | myoferlin | 0.0231868 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0231298 |
| TMSB4X | thymosin beta 4, X-linked | 0.0229432 |
| NCKAP1 | NCK-associated protein 1 | 0.0229233 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0228886 |
| PKM | pyruvate kinase, muscle | 0.0228581 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0227741 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0221511 |
| TXNRD1 | thioredoxin reductase 1 | 0.0221436 |
| AHR | aryl hydrocarbon receptor | 0.0220507 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.021961 |
| MED14 | mediator complex subunit 14 | 0.0218862 |
| NGLY1 | N-glycanase 1 | 0.0218703 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0218527 |
| RTN4 | reticulon 4 | 0.0216944 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0216197 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0215651 |
| RASA2 | RAS p21 protein activator 2 | 0.021377 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.021358 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0213395 |
| NOTCH2 | notch 2 | 0.0211895 |
| ZNF451 | zinc finger protein 451 | 0.02104 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0209987 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.02097 |
| THBS1 | thrombospondin 1 | 0.0209372 |
| PCBP2 | poly(rC) binding protein 2 | 0.0207941 |
| KLF6 | Kruppel-like factor 6 | 0.0207926 |
| CD59 | CD59 molecule, complement regulatory protein | 0.020774 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.328276 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.228255 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.169498 |
| HLA-B | major histocompatibility complex, class I, B | -0.132983 |
| NDRG1 | N-myc downstream regulated 1 | -0.131679 |
| IER3 | immediate early response 3 | -0.109062 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0978043 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0894865 |
| GLIS3 | GLIS family zinc finger 3 | -0.0872744 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0846272 |
| FTL | ferritin, light polypeptide | -0.0816872 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0801417 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0756955 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0738012 |
| TMSB10 | thymosin beta 10 | -0.0684374 |
| HMGA2 | high mobility group AT-hook 2 | -0.0668865 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0623962 |
| CDH13 | cadherin 13 | -0.0619552 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0561943 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.054649 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0545064 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0544163 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0494472 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.048029 |
| PLIN2 | perilipin 2 | -0.0474831 |
| HLA-A | major histocompatibility complex, class I, A | -0.0460198 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0450965 |
| RPS24 | ribosomal protein S24 | -0.0445012 |
| RPL36A | ribosomal protein L36a | -0.0441493 |
| RPS23 | ribosomal protein S23 | -0.0439884 |
| CTSD | cathepsin D | -0.0439253 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0431658 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0411997 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0405428 |
| INTS6 | integrator complex subunit 6 | -0.0392569 |
| EGR1 | early growth response 1 | -0.0388991 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0376042 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0375076 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0352222 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0349504 |
| TMEM132D | transmembrane protein 132D | -0.0349124 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0333679 |
| FRMD4A | FERM domain containing 4A | -0.0328854 |
| DIAPH2 | diaphanous-related formin 2 | -0.0325249 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0314645 |
| RAI14 | retinoic acid induced 14 | -0.0313048 |
| COL1A1 | collagen, type I, alpha 1 | -0.031251 |
| NAV1 | neuron navigator 1 | -0.0311976 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0310429 |
| MT2A | metallothionein 2A | -0.0304422 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0303922 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0302571 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0302534 |
| LOX | lysyl oxidase | -0.0301553 |
| RPLP2 | ribosomal protein, large, P2 | -0.0300381 |
| RPS10 | ribosomal protein S10 | -0.0296814 |
| COL5A1 | collagen, type V, alpha 1 | -0.0296112 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.029591 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0295383 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0294434 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0292088 |
| UBC | ubiquitin C | -0.0288941 |
| HLA-E | major histocompatibility complex, class I, E | -0.0282561 |
| GPC6 | glypican 6 | -0.028136 |
| GNAS | GNAS complex locus | -0.0279175 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0274814 |
| ACTG1 | actin gamma 1 | -0.0273984 |
| RPL7A | ribosomal protein L7a | -0.0273287 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0272838 |
| RPLP1 | ribosomal protein, large, P1 | -0.0271089 |
| RPS6 | ribosomal protein S6 | -0.0267844 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0263615 |
| NRN1 | neuritin 1 | -0.026184 |
| HMGA1 | high mobility group AT-hook 1 | -0.0258221 |
| PTMA | prothymosin, alpha | -0.0257683 |
| EFNA5 | ephrin-A5 | -0.0256151 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0251665 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0251391 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0249914 |
| RPS8 | ribosomal protein S8 | -0.0247878 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.024373 |
| BNC2 | basonuclin 2 | -0.0243507 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0239952 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0238624 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0237801 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0237762 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.023701 |
| RPS25 | ribosomal protein S25 | -0.023604 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0234499 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0234317 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0232017 |
| RPS15 | ribosomal protein S15 | -0.0228163 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0227125 |
| RPL31 | ribosomal protein L31 | -0.022583 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0225691 |
| IGF1R | insulin-like growth factor 1 receptor | -0.022363 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0222674 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0221077 |
| RPL28 | ribosomal protein L28 | -0.0220605 |
| RPS21 | ribosomal protein S21 | -0.0218209 |
