| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.229364 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.12974 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.123103 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0970295 |
| MYOF | myoferlin | 0.0618104 |
| FTL | ferritin, light polypeptide | 0.052883 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0518623 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0500557 |
| ASPH | aspartate beta-hydroxylase | 0.0472823 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.046956 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0429507 |
| ITGA6 | integrin, alpha 6 | 0.0394253 |
| S100A6 | S100 calcium binding protein A6 | 0.0391029 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0378194 |
| PKM | pyruvate kinase, muscle | 0.037775 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0376537 |
| TMSB4X | thymosin beta 4, X-linked | 0.0359157 |
| TMSB10 | thymosin beta 10 | 0.0358403 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0355071 |
| RPL12 | ribosomal protein L12 | 0.0350647 |
| CALR | calreticulin | 0.0349969 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0348349 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0346869 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0344776 |
| MATR3 | matrin 3 | 0.0329121 |
| FNBP1L | formin binding protein 1-like | 0.0322905 |
| DENND4A | DENN/MADD domain containing 4A | 0.0321528 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0317873 |
| EZR | ezrin | 0.0315629 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0311522 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.029957 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0297728 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0294275 |
| ENO1 | enolase 1, (alpha) | 0.0293746 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0293298 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0287593 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0286119 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0284572 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0283456 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.0282905 |
| RPS6 | ribosomal protein S6 | 0.0274228 |
| ATP13A3 | ATPase type 13A3 | 0.0272215 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0272072 |
| RPS17 | ribosomal protein S17 | 0.026846 |
| SDC4 | syndecan 4 | 0.0266606 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0265621 |
| STK4 | serine/threonine kinase 4 | 0.026518 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.026396 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0262996 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0261387 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.02593 |
| CD63 | CD63 molecule | 0.0258114 |
| RPS3 | ribosomal protein S3 | 0.0257647 |
| CD47 | CD47 molecule | 0.0256949 |
| RPL26 | ribosomal protein L26 | 0.0256076 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0255718 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0254427 |
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.0254275 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0252433 |
| PRPF39 | pre-mRNA processing factor 39 | 0.0251044 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0249861 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0249835 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0249814 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0246921 |
| TPR | translocated promoter region, nuclear basket protein | 0.0245723 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.0245615 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.024142 |
| SFTPA2 | surfactant protein A2 | 0.0239751 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0239171 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0238724 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0237583 |
| RPLP0 | ribosomal protein, large, P0 | 0.0237174 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0236043 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0235018 |
| FBXO7 | F-box protein 7 | 0.0234791 |
| SMAD3 | SMAD family member 3 | 0.0233098 |
| GDNF | glial cell derived neurotrophic factor | 0.0232442 |
| TMEM41B | transmembrane protein 41B | 0.0231606 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0231432 |
| FAF2 | Fas associated factor family member 2 | 0.0230457 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0225155 |
| TFG | TRK-fused gene | 0.0224661 |
| RPS2 | ribosomal protein S2 | 0.0224226 |
| VMP1 | vacuole membrane protein 1 | 0.0223619 |
| CDC73 | cell division cycle 73 | 0.0222411 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0221492 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.02204 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0218782 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0218527 |
| BCL2L1 | BCL2-like 1 | 0.021777 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0217183 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0214033 |
| CTSB | cathepsin B | 0.0213506 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0213102 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.021274 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0212622 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0210812 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0210661 |
| SERINC1 | serine incorporator 1 | 0.0210374 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0210075 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.366661 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.220978 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.14981 |
| FN1 | fibronectin 1 | -0.131534 |
| HLA-B | major histocompatibility complex, class I, B | -0.130663 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0990833 |
| VCL | vinculin | -0.0900673 |
| CALD1 | caldesmon 1 | -0.0758853 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0734614 |
| GLIS3 | GLIS family zinc finger 3 | -0.0727973 |
| VIM | vimentin | -0.0726247 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0692907 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.066756 |
| COL1A1 | collagen, type I, alpha 1 | -0.064997 |
| AHNAK | AHNAK nucleoprotein | -0.0642887 |
| HMGA2 | high mobility group AT-hook 2 | -0.0642154 |
| IL6 | interleukin 6 | -0.0631514 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0609331 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0607108 |
| IL6ST | interleukin 6 signal transducer | -0.060521 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0601477 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0594395 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0592319 |
| POTEF | POTE ankyrin domain family, member F | -0.0591801 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0586794 |
| CDH13 | cadherin 13 | -0.0571376 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0552607 |
| HLA-C | major histocompatibility complex, class I, C | -0.0531845 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0529275 |
| MT2A | metallothionein 2A | -0.0522695 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0509823 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0507699 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0499326 |
| DPYD | dihydropyrimidine dehydrogenase | -0.049915 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0496451 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0486931 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0485344 |
| VEGFC | vascular endothelial growth factor C | -0.0484535 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0466716 |
| MYO1E | myosin IE | -0.0448587 |
| NAV1 | neuron navigator 1 | -0.0438689 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0423366 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0420463 |
| HLA-A | major histocompatibility complex, class I, A | -0.0415242 |
| HIP1 | huntingtin interacting protein 1 | -0.0404716 |
| CDK6 | cyclin-dependent kinase 6 | -0.0400901 |
| PRELID2 | PRELI domain containing 2 | -0.0396869 |
| EGFR | epidermal growth factor receptor | -0.0395855 |
| SEPTIN7 | septin 7 | -0.0388763 |
| ITGAV | integrin, alpha V | -0.0382095 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0379926 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0377865 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0374309 |
| FNIP1 | folliculin interacting protein 1 | -0.037375 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0369879 |
| TNS3 | tensin 3 | -0.0368258 |
| UBC | ubiquitin C | -0.0365866 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0362513 |
| SRPK2 | SRSF protein kinase 2 | -0.0360741 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0360478 |
| B2M | beta-2-microglobulin | -0.0354695 |
| ANLN | anillin, actin binding protein | -0.0343213 |
| STC1 | stanniocalcin 1 | -0.0342493 |
| CCNI | cyclin I | -0.0342007 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0337673 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0333704 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0332874 |
| AHR | aryl hydrocarbon receptor | -0.0329146 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0328945 |
| RUNX1 | runt-related transcription factor 1 | -0.0328828 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0320973 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0319938 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0317332 |
| ACTG1 | actin gamma 1 | -0.0314884 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0313121 |
| FRMD4A | FERM domain containing 4A | -0.0312558 |
| LOX | lysyl oxidase | -0.0310629 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0306981 |
| STK17A | serine/threonine kinase 17a | -0.0306416 |
| RASAL2 | RAS protein activator like 2 | -0.0305895 |
| CALU | calumenin | -0.0305555 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0303512 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0300954 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.029429 |
| CLIC4 | chloride intracellular channel 4 | -0.0290831 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0290771 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0289155 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0288596 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0287582 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0286984 |
| MED13L | mediator complex subunit 13-like | -0.0286835 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0283938 |
| RHEB | Ras homolog enriched in brain | -0.0282756 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0282313 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase | -0.0280924 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0280554 |
| CCDC88A | coiled-coil domain containing 88A | -0.0280254 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0279569 |
| RRBP1 | ribosome binding protein 1 | -0.0278897 |
| KAZN | kazrin, periplakin interacting protein | -0.027747 |
