| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.126707 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.115636 |
| PKM | pyruvate kinase, muscle | 0.114168 |
| ENO1 | enolase 1, (alpha) | 0.0959287 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0858316 |
| LDHA | lactate dehydrogenase A | 0.080843 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0797203 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0749162 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0747136 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0706176 |
| GOLGA4 | golgin A4 | 0.0677655 |
| POTEF | POTE ankyrin domain family, member F | 0.0656348 |
| KIF5B | kinesin family member 5B | 0.0632289 |
| SPAG9 | sperm associated antigen 9 | 0.0619135 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0600937 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0578969 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0538226 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0521549 |
| RPS3 | ribosomal protein S3 | 0.051372 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0507619 |
| TPI1 | triosephosphate isomerase 1 | 0.050409 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0502603 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0496419 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0493222 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0484846 |
| ZNF292 | zinc finger protein 292 | 0.0469953 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0469583 |
| RPL26 | ribosomal protein L26 | 0.0468009 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0466916 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0464414 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0461051 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0455969 |
| FMNL2 | formin-like 2 | 0.0448563 |
| HSPA8 | heat shock 70kDa protein 8 | 0.044453 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0444432 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0438747 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0437274 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0436272 |
| SEC24A | SEC24 family member A | 0.0435464 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0435248 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0429844 |
| ADM | adrenomedullin | 0.0426995 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0423382 |
| LMO7 | LIM domain 7 | 0.041205 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0409891 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0403091 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0401775 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0394674 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0388874 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.038862 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0388522 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0383068 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0381322 |
| NCKAP1 | NCK-associated protein 1 | 0.0381119 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0380751 |
| CHMP4B | charged multivesicular body protein 4B | 0.0374761 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0371327 |
| NUP58 | nucleoporin 58 | 0.0371002 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0370899 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0367003 |
| CAPRIN2 | caprin family member 2 | 0.0366412 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0363457 |
| RPL37A | ribosomal protein L37a | 0.0361369 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0359068 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0355897 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0355496 |
| ASPH | aspartate beta-hydroxylase | 0.0353846 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0351776 |
| ZNF638 | zinc finger protein 638 | 0.0350949 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0349447 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0347363 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0347157 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0340941 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0339623 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0338967 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0336415 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0329393 |
| CLTC | clathrin, heavy chain (Hc) | 0.0322819 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0321608 |
| CEP250 | centrosomal protein 250kDa | 0.0320085 |
| RPS12 | ribosomal protein S12 | 0.031589 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0314965 |
| TXNIP | thioredoxin interacting protein | 0.0314953 |
| NF1 | neurofibromin 1 | 0.0313691 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0313352 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0310314 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0309997 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0309301 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0308785 |
| MORF4L2 | mortality factor 4 like 2 | 0.0308564 |
| CCNL1 | cyclin L1 | 0.0308193 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.030806 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.030693 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0306535 |
| OGA | O-GlcNAcase | 0.0305955 |
| ATP13A3 | ATPase type 13A3 | 0.0303712 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0300334 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0296343 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0295905 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.029576 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.223889 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0736178 |
| SVIL | supervillin | -0.0701207 |
| OSMR | oncostatin M receptor | -0.0656895 |
| SMYD3 | SET and MYND domain containing 3 | -0.0640802 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0630322 |
| JMJD1C | jumonji domain containing 1C | -0.0579771 |
| VCL | vinculin | -0.0579146 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0532244 |
| VIM | vimentin | -0.047332 |
| ANXA2 | annexin A2 | -0.0466456 |
| TMEM123 | transmembrane protein 123 | -0.0460417 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0440883 |
| AHNAK | AHNAK nucleoprotein | -0.0431619 |
| HLA-C | major histocompatibility complex, class I, C | -0.0427608 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0413108 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0409645 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0404484 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0401825 |
| EGR1 | early growth response 1 | -0.039269 |
| IER3 | immediate early response 3 | -0.0388178 |
| MAP1B | microtubule-associated protein 1B | -0.0382456 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0374654 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0364338 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0363692 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0359983 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0358541 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0358272 |
| ETF1 | eukaryotic translation termination factor 1 | -0.035245 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0349315 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0344701 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0343888 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0343446 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0332489 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0330935 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0330364 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0329507 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0323931 |
| RBM39 | RNA binding motif protein 39 | -0.0314939 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0312844 |
| NABP1 | nucleic acid binding protein 1 | -0.0309936 |
| TMSB10 | thymosin beta 10 | -0.0303531 |
| TOM1L2 | target of myb1-like 2 (chicken) | -0.0299057 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0298326 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.029141 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0286142 |
| TCF12 | transcription factor 12 | -0.0285677 |
| ZNF438 | zinc finger protein 438 | -0.028162 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0277721 |
| RAD51B | RAD51 paralog B | -0.0276168 |
| PRKD1 | protein kinase D1 | -0.0273186 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0272679 |
| RHEB | Ras homolog enriched in brain | -0.0272557 |
| NLK | nemo-like kinase | -0.0272358 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0269302 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0267164 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0264883 |
| HM13 | histocompatibility (minor) 13 | -0.0263515 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0262505 |
| DIDO1 | death inducer-obliterator 1 | -0.0262479 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0261988 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0260687 |
| CCNI | cyclin I | -0.0259185 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.025864 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.0258534 |
| NALCN | sodium leak channel, non selective | -0.0258368 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0255015 |
| BSG | basigin (Ok blood group) | -0.0254995 |
| CREBBP | CREB binding protein | -0.0254575 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0254253 |
| RAB27A | RAB27A, member RAS oncogene family | -0.0254251 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0253815 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0251924 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0250594 |
| CENPP | centromere protein P | -0.0249868 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0249502 |
| RPLP0 | ribosomal protein, large, P0 | -0.0249352 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0247353 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.024472 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0243847 |
| ACTG1 | actin gamma 1 | -0.0243222 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0242808 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0242107 |
| SERPINA2 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) | -0.0239287 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0238196 |
| FAF2 | Fas associated factor family member 2 | -0.0237665 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.023711 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0236813 |
| AFTPH | aftiphilin | -0.0234312 |
| LDLR | low density lipoprotein receptor | -0.0234026 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0232651 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0232031 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0231671 |
| SKIL | SKI-like proto-oncogene | -0.0231193 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0231107 |
| ADIPOR2 | adiponectin receptor 2 | -0.0228573 |
| CEP295 | centrosomal protein 295kDa | -0.0227686 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0227532 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0226764 |
| TLE5 | TLE family member 5, transcriptional modulator | -0.0226468 |
