| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Mozavaptan perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Mozavaptan_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.110291 |
| ENO1 | enolase 1, (alpha) | 0.10979 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0747787 |
| PKM | pyruvate kinase, muscle | 0.0745958 |
| STC2 | stanniocalcin 2 | 0.0723357 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0668399 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0653721 |
| TMSB4X | thymosin beta 4, X-linked | 0.0608475 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0592773 |
| CALR | calreticulin | 0.059145 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0562355 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0561111 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0556428 |
| FAT1 | FAT atypical cadherin 1 | 0.0553715 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0538154 |
| TPM3 | tropomyosin 3 | 0.0523919 |
| TXNIP | thioredoxin interacting protein | 0.0513288 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.050379 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0501556 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0490453 |
| RNF145 | ring finger protein 145 | 0.0489459 |
| ZNF292 | zinc finger protein 292 | 0.0482592 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0477735 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.047677 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0472985 |
| ZNF148 | zinc finger protein 148 | 0.0472975 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0463112 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0453576 |
| GPC6 | glypican 6 | 0.0452964 |
| CD109 | CD109 molecule | 0.0448586 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0444402 |
| NUP58 | nucleoporin 58 | 0.0440071 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0438068 |
| VEGFA | vascular endothelial growth factor A | 0.0435185 |
| FAM13A | family with sequence similarity 13, member A | 0.0418752 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0418541 |
| COPA | coatomer protein complex, subunit alpha | 0.0409786 |
| TPR | translocated promoter region, nuclear basket protein | 0.0401897 |
| AHR | aryl hydrocarbon receptor | 0.0392774 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.038474 |
| AFDN | afadin, adherens junction formation factor | 0.0383254 |
| POTEF | POTE ankyrin domain family, member F | 0.0380029 |
| CLTC | clathrin, heavy chain (Hc) | 0.0379962 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0379288 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0366174 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0364706 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0363439 |
| CCNL1 | cyclin L1 | 0.0362818 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0361173 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0359811 |
| INSIG2 | insulin induced gene 2 | 0.0351571 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0349054 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0347005 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0344933 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0340348 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0338134 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0336911 |
| ARRDC3 | arrestin domain containing 3 | 0.0327959 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0324176 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0322231 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0321627 |
| FMNL2 | formin-like 2 | 0.0321511 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0318313 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0317467 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.031428 |
| PDS5A | PDS5 cohesin associated factor A | 0.0313645 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.031289 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0303586 |
| RPL41 | ribosomal protein L41 | 0.0302589 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0299994 |
| ATP11A | ATPase, class VI, type 11A | 0.0299094 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.029757 |
| PAPOLA | poly(A) polymerase alpha | 0.0297228 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0295843 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0294565 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0294476 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0293962 |
| HYOU1 | hypoxia up-regulated 1 | 0.0292766 |
| MYO1B | myosin IB | 0.0292401 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0291397 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0290295 |
| MYOF | myoferlin | 0.0286341 |
| EGFR | epidermal growth factor receptor | 0.0285889 |
| RUNX2 | runt-related transcription factor 2 | 0.02785 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.027846 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0278266 |
| MSN | moesin | 0.027819 |
| JAK1 | Janus kinase 1 | 0.0278055 |
| ANXA5 | annexin A5 | 0.0277864 |
| ATP13A3 | ATPase type 13A3 | 0.0274066 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.02736 |
| RANBP2 | RAN binding protein 2 | 0.0271179 |
| WAC | WW domain containing adaptor with coiled-coil | 0.027105 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0269394 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0268494 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.026377 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0263721 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0262011 |
| MORF4L2 | mortality factor 4 like 2 | 0.0261926 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.026081 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.426596 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.219869 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.142657 |
| SQSTM1 | sequestosome 1 | -0.0714962 |
| HLA-B | major histocompatibility complex, class I, B | -0.063022 |
| FN1 | fibronectin 1 | -0.0624874 |
| VIM | vimentin | -0.0605548 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.060198 |
| GLIS3 | GLIS family zinc finger 3 | -0.0596138 |
| MT2A | metallothionein 2A | -0.0536795 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0535336 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0509094 |
| NDRG1 | N-myc downstream regulated 1 | -0.0507607 |
| GNAS | GNAS complex locus | -0.0504206 |
| RPS6 | ribosomal protein S6 | -0.0503302 |
| ETV1 | ets variant 1 | -0.0498147 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0472691 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0439882 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0437963 |
| RPS24 | ribosomal protein S24 | -0.0434879 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0434213 |
| SYT1 | synaptotagmin I | -0.0415542 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0415344 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0415064 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0402217 |
| RPL9 | ribosomal protein L9 | -0.0379202 |
| OSMR | oncostatin M receptor | -0.037456 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.037375 |
| FTL | ferritin, light polypeptide | -0.0370494 |
| HMGA1 | high mobility group AT-hook 1 | -0.0368292 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0353392 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0349704 |
| PTMA | prothymosin, alpha | -0.0343724 |
| RRBP1 | ribosome binding protein 1 | -0.0342111 |
| MAP1B | microtubule-associated protein 1B | -0.0341814 |
| FNBP1 | formin binding protein 1 | -0.0334255 |
| MKI67 | marker of proliferation Ki-67 | -0.0334191 |
| ETV6 | ets variant 6 | -0.0333463 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0330292 |
| CENPF | centromere protein F, 350/400kDa | -0.0326741 |
| HMGA2 | high mobility group AT-hook 2 | -0.0326441 |
| NRP1 | neuropilin 1 | -0.0324866 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0322148 |
| TMSB10 | thymosin beta 10 | -0.0321535 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0308706 |
| FOXP1 | forkhead box P1 | -0.0307843 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0305571 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0301427 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0298907 |
| S100A10 | S100 calcium binding protein A10 | -0.0297779 |
| RPLP1 | ribosomal protein, large, P1 | -0.0291444 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0291252 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0289492 |
| RPS16 | ribosomal protein S16 | -0.0287583 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0285815 |
| IER3 | immediate early response 3 | -0.0285288 |
| SVIL | supervillin | -0.0284571 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0284294 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0283107 |
| RPS8 | ribosomal protein S8 | -0.0282236 |
| RPL38 | ribosomal protein L38 | -0.0281861 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.028087 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0270518 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.026318 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0259125 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.0256692 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0255243 |
| SDCBP | syndecan binding protein (syntenin) | -0.0255085 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0254127 |
| RPL28 | ribosomal protein L28 | -0.0248958 |
| CD44 | CD44 molecule (Indian blood group) | -0.0246377 |
| S100A6 | S100 calcium binding protein A6 | -0.024293 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0242713 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.024057 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0238824 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0238519 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.02382 |
| RPS5 | ribosomal protein S5 | -0.0237033 |
| RPS28 | ribosomal protein S28 | -0.0236525 |
| RTN4 | reticulon 4 | -0.023638 |
| RIGI | RNA sensor RIG-I | -0.023541 |
| CENPE | centromere protein E, 312kDa | -0.0235272 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0233298 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0232596 |
| RPS21 | ribosomal protein S21 | -0.0231804 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0231478 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0228454 |
| BSG | basigin (Ok blood group) | -0.0228116 |
| NUMB | numb homolog (Drosophila) | -0.0226007 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0223614 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0223463 |
| RPL35A | ribosomal protein L35a | -0.0222829 |
| RPS25 | ribosomal protein S25 | -0.0222408 |
| SELENOF | selenoprotein F | -0.0221355 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0218354 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0216218 |
| TXNRD1 | thioredoxin reductase 1 | -0.0215735 |
| RANBP17 | RAN binding protein 17 | -0.021505 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0213226 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0211808 |
