Mumps Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A viral infectious disease that results_in inflammation located_in salivary gland, has_material_basis_in Mumps virus, which is transmitted_by droplet spread of saliva or mucus from the mouth, nose, or throat of an infected person, or transmitted_by contaminated fomites. The infection has_symptom fever, has_symptom headache, has_symptom muscle aches, has_symptom tiredness, has_symptom loss of appetite, has_symptom swollen and tender salivary glands under the ears or jaw on one or both sides of the face. (Human Disease Ontology, DOID_10264)
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Genes

376 genes co-occuring with the disease Mumps in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
MFSD6 major facilitator superfamily domain containing 6 3.2
CD4 CD4 molecule 2.753
CD8A CD8a molecule 2.629
ACE2 angiotensin I converting enzyme 2 2.6
IFNG interferon, gamma 2.57
AMHR2 anti-Mullerian hormone receptor, type II 2.517
IFNA1 interferon, alpha 1 2.414
TNF tumor necrosis factor 2.341
IL6 interleukin 6 2.327
IL2 interleukin 2 2.283
STAT2 signal transducer and activator of transcription 2, 113kDa 2.259
TMPRSS2 transmembrane protease, serine 2 2.239
IL10 interleukin 10 2.225
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.224
CRP C-reactive protein, pentraxin-related 2.22
IFNB1 interferon, beta 1, fibroblast 2.201
TLR3 toll-like receptor 3 2.197
TLR7 toll-like receptor 7 2.174
CD46 CD46 molecule, complement regulatory protein 2.173
CD19 CD19 molecule 2.158
IL4 interleukin 4 2.15
IL1B interleukin 1, beta 2.148
IFNAR2 interferon (alpha, beta and omega) receptor 2 2.135
ERVW-1 endogenous retrovirus group W, member 1 2.134
IRF9 interferon regulatory factor 9 2.133
IFIH1 interferon induced with helicase C domain 1 2.112
STAT1 signal transducer and activator of transcription 1, 91kDa 2.065
FURIN furin (paired basic amino acid cleaving enzyme) 2.017
CD27 CD27 molecule 2.008
ALB albumin 2.006
SLAMF1 signaling lymphocytic activation molecule family member 1 2.005
IFNA2 interferon, alpha 2 1.977
IRF7 interferon regulatory factor 7 1.963
IL17A interleukin 17A 1.946
TLR9 toll-like receptor 9 1.941
IRF3 interferon regulatory factor 3 1.913
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.911
MOG myelin oligodendrocyte glycoprotein 1.906
TLR4 toll-like receptor 4 1.897
HLA-B major histocompatibility complex, class I, B 1.891
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 1.886
IL1A interleukin 1, alpha 1.879
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 1.877
CXCL10 chemokine (C-X-C motif) ligand 10 1.867
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 1.865
CXCL8 chemokine (C-X-C motif) ligand 8 1.857
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.853
ERV3-1 endogenous retrovirus group 3, member 1 1.845
IL5 interleukin 5 1.844
ERVFRD-1 endogenous retrovirus group FRD, member 1 1.844
ACE angiotensin I converting enzyme 1.84
HLA-A major histocompatibility complex, class I, A 1.837
NECTIN4 nectin cell adhesion molecule 4 1.836
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.835
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1.824
SH2D3A SH2 domain containing 3A 1.805
TLR8 toll-like receptor 8 1.798
MX1 MX dynamin-like GTPase 1 1.79
IFNL1 interferon, lambda 1 1.783
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.779
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1.775
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1.774
MYBPH myosin binding protein H 1.773
IL13 interleukin 13 1.771
INS insulin 1.77
TLR2 toll-like receptor 2 1.768
MBP myelin basic protein 1.766
ISG15 ISG15 ubiquitin-like modifier 1.761
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.759
TYK2 tyrosine kinase 2 1.753
CD80 CD80 molecule 1.751
CCL2 chemokine (C-C motif) ligand 2 1.733
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.729
CD38 CD38 molecule 1.725
IL7 interleukin 7 1.72
CCR7 chemokine (C-C motif) receptor 7 1.712
IFNA17 interferon, alpha 17 1.709
MYOM2 myomesin 2 1.701
MAVS mitochondrial antiviral signaling protein 1.696
IFNA13 interferon, alpha 13 1.694
IFNA4 interferon, alpha 4 1.692
IL18 interleukin 18 1.688
CD40LG CD40 ligand 1.687
IFNA21 interferon, alpha 21 1.678
CD28 CD28 molecule 1.672
PF4 platelet factor 4 1.668
IFNA5 interferon, alpha 5 1.666
CD209 CD209 molecule 1.662
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 1.661
IFNA10 interferon, alpha 10 1.658
IFNA6 interferon, alpha 6 1.657
IFNA8 interferon, alpha 8 1.657
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.657
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 1.656
IFNA16 interferon, alpha 16 1.654
IFNA7 interferon, alpha 7 1.653
IFNA14 interferon, alpha 14 1.653
IL12RB1 interleukin 12 receptor, beta 1 1.649
IFI44L interferon-induced protein 44-like 1.648
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.638
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.633
UNC93B1 unc-93 homolog B1 (C. elegans) 1.623
NCAM1 neural cell adhesion molecule 1 1.618
CD69 CD69 molecule 1.615
CCL3 chemokine (C-C motif) ligand 3 1.614
CD86 CD86 molecule 1.612
CD40 CD40 molecule, TNF receptor superfamily member 5 1.606
MYD88 myeloid differentiation primary response 88 1.604
JAK1 Janus kinase 1 1.604
ANO3 anoctamin 3 1.588
FCGRT Fc fragment of IgG, receptor, transporter, alpha 1.581
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 1.579
PRF1 perforin 1 (pore forming protein) 1.579
HLA-C major histocompatibility complex, class I, C 1.575
IL15 interleukin 15 1.569
OTOF otoferlin 1.567
PXDNL peroxidasin-like 1.556
PXDN peroxidasin 1.555
CSF3 colony stimulating factor 3 (granulocyte) 1.551
FOXP3 forkhead box P3 1.548
PRTN3 proteinase 3 1.544
TBK1 TANK-binding kinase 1 1.543
SH2D3C SH2 domain containing 3C 1.542
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 1.542
USP18 ubiquitin specific peptidase 18 1.54
TGFB1 transforming growth factor, beta 1 1.539
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 1.537
CCL5 chemokine (C-C motif) ligand 5 1.534
OCA2 oculocutaneous albinism II 1.533
ADAR adenosine deaminase, RNA-specific 1.531
C3 complement component 3 1.528
PFAS phosphoribosylformylglycinamidine synthase 1.527
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 1.525
IL10RB interleukin 10 receptor, beta 1.525
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.518
ENPEP glutamyl aminopeptidase (aminopeptidase A) 1.517
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 1.507
TPO thyroid peroxidase 1.505
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.505
TG thyroglobulin 1.495
FUT2 fucosyltransferase 2 (secretor status included) 1.49
IL12RB2 interleukin 12 receptor, beta 2 1.49
RSAD2 radical S-adenosyl methionine domain containing 2 1.49
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 1.487
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 1.486
TLR5 toll-like receptor 5 1.476
IL2RA interleukin 2 receptor, alpha 1.462
IL22 interleukin 22 1.46
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) 1.451
PTPRC protein tyrosine phosphatase, receptor type, C 1.444
CXCR5 chemokine (C-X-C motif) receptor 5 1.444
IRF1 interferon regulatory factor 1 1.44
CCL4 chemokine (C-C motif) ligand 4 1.439
CXCR3 chemokine (C-X-C motif) receptor 3 1.435
LAMP1 lysosomal-associated membrane protein 1 1.435
AMH anti-Mullerian hormone 1.435
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 1.434
SCN1A sodium channel, voltage gated, type I alpha subunit 1.431
IFNE interferon, epsilon 1.429
FIMP1 fertilization-influencing membrane protein 1 1.419
GJB2 gap junction protein, beta 2, 26kDa 1.418
CTSL cathepsin L 1.415
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 1.414
CNTNAP2 contactin associated protein-like 2 1.413
DOCK8 dedicator of cytokinesis 8 1.409
F2 coagulation factor II (thrombin) 1.406
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.4
IFNK interferon, kappa 1.4
LTF lactotransferrin 1.399
F3 coagulation factor III (thromboplastin, tissue factor) 1.397
MUC1 mucin 1, cell surface associated 1.394
SELL selectin L 1.394
IFNLR1 interferon, lambda receptor 1 1.392
SLC26A5 solute carrier family 26 (anion exchanger), member 5 1.382
BCR breakpoint cluster region 1.371
PF4V1 platelet factor 4 variant 1 1.368
CLEC7A C-type lectin domain family 7, member A 1.365
IL7R interleukin 7 receptor 1.362
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 1.36
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.355
ADA adenosine deaminase 1.353
INSM2 insulinoma-associated 2 1.353
RAG1 recombination activating gene 1 1.347
LGI1 leucine-rich, glioma inactivated 1 1.346
ERCC6 excision repair cross-complementation group 6 1.345
CXCL9 chemokine (C-X-C motif) ligand 9 1.341
NLRP3 NLR family, pyrin domain containing 3 1.341
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 1.338
SDC1 syndecan 1 1.333
PRL prolactin 1.327
TRAF3 TNF receptor-associated factor 3 1.321
NOD2 nucleotide-binding oligomerization domain containing 2 1.318
C4A complement component 4A (Rodgers blood group) 1.318
BSG basigin (Ok blood group) 1.312
ICAM1 intercellular adhesion molecule 1 1.309
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 1.306
NTN5 netrin 5 1.306
MBL2 mannose-binding lectin (protein C) 2, soluble 1.305
PRSS57 protease, serine, 57 1.304
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 1.302
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.299
CD274 CD274 molecule 1.298
PTPRN protein tyrosine phosphatase, receptor type, N 1.296
TOR1A torsin family 1, member A (torsin A) 1.295
CXCR4 chemokine (C-X-C motif) receptor 4 1.294
TICAM1 toll-like receptor adaptor molecule 1 1.284
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 1.284
MPO myeloperoxidase 1.284
PNMA2 paraneoplastic Ma antigen 2 1.275
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.272
REN renin 1.272
IL9 interleukin 9 1.27
TRIM5 tripartite motif containing 5 1.263
POMC proopiomelanocortin 1.263
PVR poliovirus receptor 1.261
IFNL2 interferon, lambda 2 1.26
RCVRN recoverin 1.251
GYPC glycophorin C (Gerbich blood group) 1.249
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 1.249
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 1.247
TLR1 toll-like receptor 1 1.247
DPP10 dipeptidyl-peptidase 10 (non-functional) 1.246
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 1.245
SCN2A sodium channel, voltage gated, type II alpha subunit 1.244
IFI27 interferon, alpha-inducible protein 27 1.242
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.239
GP2 glycoprotein 2 (zymogen granule membrane) 1.238
IL10RA interleukin 10 receptor, alpha 1.236
NECTIN1 nectin cell adhesion molecule 1 1.236
CD68 CD68 molecule 1.229
ICOS inducible T-cell co-stimulator 1.228
IFNGR1 interferon gamma receptor 1 1.227
LALBA lactalbumin, alpha- 1.227
EFNB3 ephrin-B3 1.224
EFNB2 ephrin-B2 1.223
HSPA4 heat shock 70kDa protein 4 1.222
SPATC1 spermatogenesis and centriole associated 1 1.222
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 1.222
IRAK4 interleukin-1 receptor-associated kinase 4 1.211
CD1C CD1c molecule 1.21
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 1.206
LTA lymphotoxin alpha 1.205
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 1.201
B3GAT1 beta-1,3-glucuronyltransferase 1 1.199
GTPBP1 GTP binding protein 1 1.198
NELFCD negative elongation factor complex member C/D 1.194
IL4R interleukin 4 receptor 1.192
DDB1 damage-specific DNA binding protein 1, 127kDa 1.192
LST1 leukocyte specific transcript 1 1.189
TRIM21 tripartite motif containing 21 1.187
HP haptoglobin 1.185
IL1R1 interleukin 1 receptor, type I 1.184
DPP4 dipeptidyl-peptidase 4 1.176
CKB creatine kinase, brain 1.176
AIRE autoimmune regulator 1.175
ACTB actin, beta 1.175
CKM creatine kinase, muscle 1.174
CLEC4M C-type lectin domain family 4, member M 1.174
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.171
CKMT1B creatine kinase, mitochondrial 1B 1.17
BST2 bone marrow stromal cell antigen 2 1.17
JUN jun proto-oncogene 1.168
CX3CR1 chemokine (C-X3-C motif) receptor 1 1.164
DPP6 dipeptidyl-peptidase 6 1.162
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.157
TBX21 T-box 21 1.156
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 1.155
JAGN1 jagunal homolog 1 (Drosophila) 1.155
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.154
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.154
CREM cAMP responsive element modulator 1.153
PRSS1 protease, serine, 1 (trypsin 1) 1.151
CD276 CD276 molecule 1.15
CFP complement factor properdin 1.146
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.146
CD52 CD52 molecule 1.144
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.137
BTK Bruton agammaglobulinemia tyrosine kinase 1.133
APOBEC3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D 1.133
B2M beta-2-microglobulin 1.131
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1.13
CTRL chymotrypsin-like 1.128
CTRB2 chymotrypsinogen B2 1.127
LOC102723407 putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8 1.126
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 1.126
FASLG Fas ligand (TNF superfamily, member 6) 1.125
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.125
CTRB1 chymotrypsinogen B1 1.121
SLC30A10 solute carrier family 30, member 10 1.119
GJB6 gap junction protein, beta 6, 30kDa 1.118
THPO thrombopoietin 1.118
FAM3B family with sequence similarity 3, member B 1.116
TP53 tumor protein p53 1.114
CCR6 chemokine (C-C motif) receptor 6 1.113
MX2 MX dynamin-like GTPase 2 1.113
CD81 CD81 molecule 1.111
CD5 CD5 molecule 1.107
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.105
IFNL3 interferon, lambda 3 1.104
PIGR polymeric immunoglobulin receptor 1.101
ENTHD1 ENTH domain containing 1 1.101
RRM1 ribonucleotide reductase M1 1.101
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.099
IL33 interleukin 33 1.095
BCL2 B-cell CLL/lymphoma 2 1.095
GNLY granulysin 1.091
IFI44 interferon-induced protein 44 1.091
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.089
MVP major vault protein 1.088
IL2RG interleukin 2 receptor, gamma 1.086
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 1.085
CATSPER1 cation channel, sperm associated 1 1.084
TGM2 transglutaminase 2 1.084
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.083
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 1.083
CD34 CD34 molecule 1.083
PRDM1 PR domain containing 1, with ZNF domain 1.081
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.08
OSTF1 osteoclast stimulating factor 1 1.079
ST7 suppression of tumorigenicity 7 1.077
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.075
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.074
CUL4A cullin 4A 1.074
SPINK1 serine peptidase inhibitor, Kazal type 1 1.073
CCR2 chemokine (C-C motif) receptor 2 1.07
TRIM22 tripartite motif containing 22 1.067
IL17F interleukin 17F 1.067
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.065
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.063
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 1.062
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.062
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.06
CD83 CD83 molecule 1.06
CTSB cathepsin B 1.06
THBD thrombomodulin 1.057
HMGB1 high mobility group box 1 1.057
CTSS cathepsin S 1.057
C4B complement component 4B (Chido blood group) 1.054
TRAT1 T cell receptor associated transmembrane adaptor 1 1.054
MOGS mannosyl-oligosaccharide glucosidase 1.054
AICDA activation-induced cytidine deaminase 1.05
CD44 CD44 molecule (Indian blood group) 1.049
LIM2 lens intrinsic membrane protein 2, 19kDa 1.049
PDCD1 programmed cell death 1 1.048
JAK2 Janus kinase 2 1.048
TTR transthyretin 1.047
CCRL2 chemokine (C-C motif) receptor-like 2 1.045
IL3RA interleukin 3 receptor, alpha (low affinity) 1.044
AMY1B amylase, alpha 1B (salivary) 1.043
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 1.042
CYBC1 cytochrome b-245 chaperone 1 1.04
FAS Fas cell surface death receptor 1.039
GUSB glucuronidase, beta 1.037
IKZF1 IKAROS family zinc finger 1 (Ikaros) 1.036
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.036
MRC1 mannose receptor, C type 1 1.036
SSB Sjogren syndrome antigen B (autoantigen La) 1.036
AAK1 AP2 associated kinase 1 1.033
RARB retinoic acid receptor, beta 1.032
NCR1 natural cytotoxicity triggering receptor 1 1.031
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.031
ACKR2 atypical chemokine receptor 2 1.027
JAK3 Janus kinase 3 1.024
IL6R interleukin 6 receptor 1.024
CD1D CD1d molecule 1.02
CGAS cyclic GMP-AMP synthase 1.018
RAG2 recombination activating gene 2 1.015
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.014
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 1.012
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 1.012
ICAM3 intercellular adhesion molecule 3 1.011
SOCS1 suppressor of cytokine signaling 1 1.01
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.009
CLEC4E C-type lectin domain family 4, member E 1.008
CXCL12 chemokine (C-X-C motif) ligand 12 1.005
SHBG sex hormone-binding globulin 1.004