Muscle contraction Gene Set

Dataset Reactome Pathways 2014
Category structural or functional annotations
Type pathway
Description A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. (Gene Ontology, GO_0006936)
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-397014
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Genes

49 proteins participating in the Muscle contraction pathway from the Reactome Pathways dataset.

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTN2 actinin, alpha 2
ACTN3 actinin, alpha 3 (gene/pseudogene)
CALD1 caldesmon 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
DES desmin
DMD dystrophin
ITGA1 integrin, alpha 1
ITGB5 integrin, beta 5
LMOD1 leiomodin 1 (smooth muscle)
MYBPC1 myosin binding protein C, slow type
MYBPC2 myosin binding protein C, fast type
MYBPC3 myosin binding protein C, cardiac
MYH11 myosin, heavy chain 11, smooth muscle
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
MYL1 myosin, light chain 1, alkali; skeletal, fast
MYL12B myosin, light chain 12B, regulatory
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle
MYL9 myosin, light chain 9, regulatory
MYLK myosin light chain kinase
NEB nebulin
PXN paxillin
SORBS1 sorbin and SH3 domain containing 1
SORBS3 sorbin and SH3 domain containing 3
TCAP titin-cap
TLN1 talin 1
TMOD1 tropomodulin 1
TNNC1 troponin C type 1 (slow)
TNNC2 troponin C type 2 (fast)
TNNI1 troponin I type 1 (skeletal, slow)
TNNI2 troponin I type 2 (skeletal, fast)
TNNI3 troponin I type 3 (cardiac)
TNNT1 troponin T type 1 (skeletal, slow)
TNNT2 troponin T type 2 (cardiac)
TNNT3 troponin T type 3 (skeletal, fast)
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TPM3 tropomyosin 3
TPM4 tropomyosin 4
TTN titin
VCL vinculin
VIM vimentin