Myositis Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description An inflammatory process affecting the skeletal muscles. Causes include infections, injuries, and autoimmune disorders.|Inflammation of a muscle or muscle tissue. (Experimental Factor Ontology, EFO_0000783)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D009220
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Genes

729 genes/proteins associated with the disease Myositis from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
IL1RN interleukin 1 receptor antagonist 2.88009
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker) 2.88009
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) 2.88009
IGKC immunoglobulin kappa constant 2.88009
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.16214
IFNG interferon, gamma 2.12773
TNF tumor necrosis factor 2.10863
IGF1 insulin-like growth factor 1 (somatomedin C) 2.04792
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.04031
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.97771
CAT catalase 1.94422
CCL2 chemokine (C-C motif) ligand 2 1.92944
JUN jun proto-oncogene 1.91797
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.91384
IL6 interleukin 6 1.91217
PPARA peroxisome proliferator-activated receptor alpha 1.90242
PPARG peroxisome proliferator-activated receptor gamma 1.87725
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.87294
TGFB1 transforming growth factor, beta 1 1.87244
FOS FBJ murine osteosarcoma viral oncogene homolog 1.86637
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.8662
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.86427
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.84108
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.82919
APOE apolipoprotein E 1.82814
HMOX1 heme oxygenase 1 1.80999
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.80775
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.8051
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.80247
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.80153
POR P450 (cytochrome) oxidoreductase 1.79579
VCAM1 vascular cell adhesion molecule 1 1.79044
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.77878
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.77101
BCL2L1 BCL2-like 1 1.77043
EGR1 early growth response 1 1.76655
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.7621
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.76111
BCL2 B-cell CLL/lymphoma 2 1.75201
APOA1 apolipoprotein A-I 1.73758
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.73536
MMP9 matrix metallopeptidase 9 1.72968
BAX BCL2-associated X protein 1.72014
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.71932
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.71891
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.7185
GADD45A growth arrest and DNA-damage-inducible, alpha 1.71708
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.71565
COL1A1 collagen, type I, alpha 1 1.7014
VEGFA vascular endothelial growth factor A 1.68485
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.68379
FAS Fas cell surface death receptor 1.67376
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.67268
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.67246
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.67051
VCAN versican 1.66641
LDLR low density lipoprotein receptor 1.65753
MPO myeloperoxidase 1.65731
IL1B interleukin 1, beta 1.65336
TP53 tumor protein p53 1.65249
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.64033
RHOA ras homolog family member A 1.63966
NOS2 nitric oxide synthase 2, inducible 1.63877
NOS3 nitric oxide synthase 3 (endothelial cell) 1.63563
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.63563
ANXA5 annexin A5 1.63451
MAPK3 mitogen-activated protein kinase 3 1.6325
CCNG1 cyclin G1 1.63094
CFLAR CASP8 and FADD-like apoptosis regulator 1.62601
ANGPTL4 angiopoietin-like 4 1.62445
CCND3 cyclin D3 1.62106
CXCL8 chemokine (C-X-C motif) ligand 8 1.61529
INSIG1 insulin induced gene 1 1.6146
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.60967
CDK4 cyclin-dependent kinase 4 1.6036
FASN fatty acid synthase 1.60244
LPL lipoprotein lipase 1.60128
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.60128
E2F1 E2F transcription factor 1 1.59731
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.59544
SCARB1 scavenger receptor class B, member 1 1.58537
PCNA proliferating cell nuclear antigen 1.58467
GSN gelsolin 1.58444
CCNA2 cyclin A2 1.58303
ICAM1 intercellular adhesion molecule 1 1.57306
CDK2 cyclin-dependent kinase 2 1.57257
CP ceruloplasmin (ferroxidase) 1.56947
FN1 fibronectin 1 1.56851
EDN1 endothelin 1 1.56361
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.56239
GNAS GNAS complex locus 1.55723
S100A9 S100 calcium binding protein A9 1.54354
MAPK1 mitogen-activated protein kinase 1 1.53941
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.53724
GSK3B glycogen synthase kinase 3 beta 1.53627
MMP2 matrix metallopeptidase 2 1.53481
IL4 interleukin 4 1.53481
SLCO1B1 solute carrier organic anion transporter family, member 1B1 1.53431
HSPA8 heat shock 70kDa protein 8 1.53086
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.53086
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.53086
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.52987
SPP1 secreted phosphoprotein 1 1.52889
RUNX2 runt-related transcription factor 2 1.52889
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.52889
S100A8 S100 calcium binding protein A8 1.5254
STMN1 stathmin 1 1.5254
BIRC5 baculoviral IAP repeat containing 5 1.52262
CYBA cytochrome b-245, alpha polypeptide 1.51835
APOB apolipoprotein B 1.51305
FBXO32 F-box protein 32 1.50953
ANXA4 annexin A4 1.50953
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.50852
C1QBP complement component 1, q subcomponent binding protein 1.50549
FADS1 fatty acid desaturase 1 1.50423
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.50348
CCNB1 cyclin B1 1.49992
CCND1 cyclin D1 1.49508
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.49226
HSDL2 hydroxysteroid dehydrogenase like 2 1.49226
RB1 retinoblastoma 1 1.49226
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.49174
CYCS cytochrome c, somatic 1.48479
KLF10 Kruppel-like factor 10 1.48428
CXCL10 chemokine (C-X-C motif) ligand 10 1.48376
ECH1 enoyl CoA hydratase 1, peroxisomal 1.48196
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.48196
APP amyloid beta (A4) precursor protein 1.47991
CCNE1 cyclin E1 1.47966
XBP1 X-box binding protein 1 1.47889
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.47736
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.47296
CHEK1 checkpoint kinase 1 1.47296
IL1A interleukin 1, alpha 1.46648
TF transferrin 1.46542
CD14 CD14 molecule 1.46542
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.46146
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 1.46093
NFE2L2 nuclear factor, erythroid 2-like 2 1.46067
FADS2 fatty acid desaturase 2 1.4591
HMHA1 histocompatibility (minor) HA-1 1.45857
PHYH phytanoyl-CoA 2-hydroxylase 1.45723
ATF3 activating transcription factor 3 1.45643
MAPK14 mitogen-activated protein kinase 14 1.45537
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.45115
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.44599
DDIT3 DNA-damage-inducible transcript 3 1.44436
ALB albumin 1.44355
F2 coagulation factor II (thrombin) 1.44246
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.44219
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.44084
INS insulin 1.44029
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.43974
EFNB3 ephrin-B3 1.43782
TRADD TNFRSF1A-associated via death domain 1.43591
CCL5 chemokine (C-C motif) ligand 5 1.43537
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.4313
EGFR epidermal growth factor receptor 1.43021
TAGLN transgelin 1.4294
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.42859
PLTP phospholipid transfer protein 1.42589
CTSL cathepsin L 1.42562
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.42374
BMP2 bone morphogenetic protein 2 1.42347
ACADVL acyl-CoA dehydrogenase, very long chain 1.42266
ACADL acyl-CoA dehydrogenase, long chain 1.42266
LEP leptin 1.42101
ARNTL aryl hydrocarbon receptor nuclear translocator-like 1.41938
PRDX2 peroxiredoxin 2 1.41775
LOX lysyl oxidase 1.41586
TIMP1 TIMP metallopeptidase inhibitor 1 1.41559
MAPK8 mitogen-activated protein kinase 8 1.41424
COL11A1 collagen, type XI, alpha 1 1.41313
MKI67 marker of proliferation Ki-67 1.41313
EDNRA endothelin receptor type A 1.41202
CDKN2A cyclin-dependent kinase inhibitor 2A 1.41063
ERP29 endoplasmic reticulum protein 29 1.41008
CTGF connective tissue growth factor 1.40925
SREBF2 sterol regulatory element binding transcription factor 2 1.40705
ACACB acetyl-CoA carboxylase beta 1.40705
PLAT plasminogen activator, tissue 1.40316
ARG1 arginase 1 1.40092
DGAT1 diacylglycerol O-acyltransferase 1 1.40092
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 1.40092
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.40064
ECI1 enoyl-CoA delta isomerase 1 1.39813
STAT1 signal transducer and activator of transcription 1, 91kDa 1.39702
VIM vimentin 1.39451
FASLG Fas ligand (TNF superfamily, member 6) 1.39198
RARA retinoic acid receptor, alpha 1.39002
CKM creatine kinase, muscle 1.38946
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.38724
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 1.38641
SOD1 superoxide dismutase 1, soluble 1.38128
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.37817
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.37817
DUSP1 dual specificity phosphatase 1 1.37789
HES5 hes family bHLH transcription factor 5 1.37561
RRM2 ribonucleotide reductase M2 1.37446
KRT8 keratin 8, type II 1.37303
ANXA1 annexin A1 1.37132
CPT2 carnitine palmitoyltransferase 2 1.37018
TUBB3 tubulin, beta 3 class III 1.37018
PDIA4 protein disulfide isomerase family A, member 4 1.36735
TGFB2 transforming growth factor, beta 2 1.36304
CD83 CD83 molecule 1.36218
NDRG1 N-myc downstream regulated 1 1.35821
ALPL alkaline phosphatase, liver/bone/kidney 1.35821
SELE selectin E 1.35676
BID BH3 interacting domain death agonist 1.3556
SGK1 serum/glucocorticoid regulated kinase 1 1.35357
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 1.35213
CXCR4 chemokine (C-X-C motif) receptor 4 1.35041
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.34723
KCNK1 potassium channel, two pore domain subfamily K, member 1 1.34314
BTG2 BTG family, member 2 1.34285
GJB1 gap junction protein, beta 1, 32kDa 1.34227
HADH hydroxyacyl-CoA dehydrogenase 1.34227
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.34169
ATF4 activating transcription factor 4 1.34111
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.33966
CPT1A carnitine palmitoyltransferase 1A (liver) 1.3382
CAV1 caveolin 1, caveolae protein, 22kDa 1.33672
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.33523
IGF1R insulin-like growth factor 1 receptor 1.33228
FSCN1 fascin actin-bundling protein 1 1.33052
FABP5 fatty acid binding protein 5 (psoriasis-associated) 1.33052
NQO1 NAD(P)H dehydrogenase, quinone 1 1.32816
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.32816
FOSL1 FOS-like antigen 1 1.32637
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 1.32607
BDNF brain-derived neurotrophic factor 1.32428
COL1A2 collagen, type I, alpha 2 1.32339
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 1.32221
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.31506
SERINC3 serine incorporator 3 1.31476
CDK5 cyclin-dependent kinase 5 1.31476
ENPEP glutamyl aminopeptidase (aminopeptidase A) 1.31446
POMC proopiomelanocortin 1.31446
HMGB2 high mobility group box 2 1.31267
ELOVL6 ELOVL fatty acid elongase 6 1.31267
NCOA1 nuclear receptor coactivator 1 1.31267
LIF leukemia inhibitory factor 1.31267
GLDC glycine dehydrogenase (decarboxylating) 1.31089
G0S2 G0/G1 switch 2 1.31059
SRGN serglycin 1.31059
CLCN4 chloride channel, voltage-sensitive 4 1.30911
PGRMC1 progesterone receptor membrane component 1 1.30696
COL12A1 collagen, type XII, alpha 1 1.30696
MGP matrix Gla protein 1.30635
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.3039
ISYNA1 inositol-3-phosphate synthase 1 1.30329
NRP1 neuropilin 1 1.30208
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.29966
SPON2 spondin 2, extracellular matrix protein 1.29936
TMSB4X thymosin beta 4, X-linked 1.29595
A2M alpha-2-macroglobulin 1.29564
INSR insulin receptor 1.29379
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 1.29348
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.29194
RHOB ras homolog family member B 1.29164
FMO1 flavin containing monooxygenase 1 1.29164
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.2895
HMGB1 high mobility group box 1 1.2895
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.28889
FKBP5 FK506 binding protein 5 1.28549
SOD2 superoxide dismutase 2, mitochondrial 1.2818
TPM1 tropomyosin 1 (alpha) 1.28149
TMEM97 transmembrane protein 97 1.27845
EGR2 early growth response 2 1.27564
PDK4 pyruvate dehydrogenase kinase, isozyme 4 1.27564
CD36 CD36 molecule (thrombospondin receptor) 1.27533
CALB1 calbindin 1, 28kDa 1.27502
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.27378
IL18 interleukin 18 1.27255
GDF15 growth differentiation factor 15 1.27255
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.27255
G6PC glucose-6-phosphatase, catalytic subunit 1.27193
FABP2 fatty acid binding protein 2, intestinal 1.27193
PC pyruvate carboxylase 1.27193
BAD BCL2-associated agonist of cell death 1.27162
TLR4 toll-like receptor 4 1.26917
PPARD peroxisome proliferator-activated receptor delta 1.26825
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.26763
GJA1 gap junction protein, alpha 1, 43kDa 1.26669
LGALS3 lectin, galactoside-binding, soluble, 3 1.26638
HBEGF heparin-binding EGF-like growth factor 1.26452
XDH xanthine dehydrogenase 1.26421
CLU clusterin 1.26421
CA3 carbonic anhydrase III 1.26236
GSTP1 glutathione S-transferase pi 1 1.26083
CALR calreticulin 1.26083
HRAS Harvey rat sarcoma viral oncogene homolog 1.2596
TFRC transferrin receptor 1.2596
SREBF1 sterol regulatory element binding transcription factor 1 1.25713
RELN reelin 1.25619
BCL3 B-cell CLL/lymphoma 3 1.25619
RUNX1 runt-related transcription factor 1 1.25619
ALAS2 5'-aminolevulinate synthase 2 1.25619
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.25557
RAD51 RAD51 recombinase 1.25369
AK4 adenylate kinase 4 1.25307
BCAT1 branched chain amino-acid transaminase 1, cytosolic 1.24997
ODC1 ornithine decarboxylase 1 1.24905
EPHX2 epoxide hydrolase 2, cytoplasmic 1.24843
THBS1 thrombospondin 1 1.24843
KRT18 keratin 18, type I 1.24687
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.24496
DBP D site of albumin promoter (albumin D-box) binding protein 1.24433
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.24338
FGF21 fibroblast growth factor 21 1.2415
ACACA acetyl-CoA carboxylase alpha 1.2415
FABP1 fatty acid binding protein 1, liver 1.23993
NPPB natriuretic peptide B 1.23993
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.23837
CDO1 cysteine dioxygenase type 1 1.23837
SDC2 syndecan 2 1.23837
ACSL1 acyl-CoA synthetase long-chain family member 1 1.23648
FMOD fibromodulin 1.23584
WNT4 wingless-type MMTV integration site family, member 4 1.23552
LHB luteinizing hormone beta polypeptide 1.23328
IRS1 insulin receptor substrate 1 1.23328
CYR61 cysteine-rich, angiogenic inducer, 61 1.23328
SDC1 syndecan 1 1.23265
AKAP12 A kinase (PRKA) anchor protein 12 1.23265
SRXN1 sulfiredoxin 1 1.23169
APOC3 apolipoprotein C-III 1.23042
CCNB2 cyclin B2 1.22979
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 1.22979
MGST1 microsomal glutathione S-transferase 1 1.22821
ACTA2 actin, alpha 2, smooth muscle, aorta 1.2279
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 1.22758
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 1.22696
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.22501
KLF2 Kruppel-like factor 2 1.22469
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.22339
NPY neuropeptide Y 1.22339
CFD complement factor D (adipsin) 1.22177
CCL3 chemokine (C-C motif) ligand 3 1.22145
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.22016
RGS4 regulator of G-protein signaling 4 1.21919
ERRFI1 ERBB receptor feedback inhibitor 1 1.21919
PRL prolactin 1.21919
SCG2 secretogranin II 1.21919
MAOA monoamine oxidase A 1.21855
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.21855
HDC histidine decarboxylase 1.21663
EFNA1 ephrin-A1 1.21402
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 1.21402
LHX2 LIM homeobox 2 1.21402
COL15A1 collagen, type XV, alpha 1 1.21402
MAP3K4 mitogen-activated protein kinase kinase kinase 4 1.2137
EPCAM epithelial cell adhesion molecule 1.2137
FBP1 fructose-1,6-bisphosphatase 1 1.21141
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.21141
F3 coagulation factor III (thromboplastin, tissue factor) 1.20913
ASS1 argininosuccinate synthase 1 1.20881
S100A10 S100 calcium binding protein A10 1.20848
CCND2 cyclin D2 1.20751
CYP3A cytochrome P450, family 3, subfamily A 1.20654
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 1.20622
IL12A interleukin 12A 1.20622
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.20622
TRIB3 tribbles pseudokinase 3 1.2046
IGFBP1 insulin-like growth factor binding protein 1 1.20295
CTSB cathepsin B 1.20295
LCN2 lipocalin 2 1.20295
MGMT O-6-methylguanine-DNA methyltransferase 1.20163
ADRB3 adrenoceptor beta 3 1.2013
TAT tyrosine aminotransferase 1.20097
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 1.19933
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1.199
ACAA2 acetyl-CoA acyltransferase 2 1.19868
IGFBP4 insulin-like growth factor binding protein 4 1.19835
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 1.19412
FRMD4A FERM domain containing 4A 1.19412
FAM107A family with sequence similarity 107, member A 1.19412
CD44 CD44 molecule (Indian blood group) 1.19246
COL4A1 collagen, type IV, alpha 1 1.19146
FABP4 fatty acid binding protein 4, adipocyte 1.18981
TIMP2 TIMP metallopeptidase inhibitor 2 1.18981
CLDN1 claudin 1 1.18882
MMP3 matrix metallopeptidase 3 1.18816
GPX1 glutathione peroxidase 1 1.18783
GSTO1 glutathione S-transferase omega 1 1.18652
HP haptoglobin 1.18652
GRN granulin 1.18652
CDK1 cyclin-dependent kinase 1 1.18587
FLOT1 flotillin 1 1.18554
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 1.18521
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.18521
SQSTM1 sequestosome 1 1.18521
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 1.18489
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 1.18489
CDC42 cell division cycle 42 1.18424
MCM4 minichromosome maintenance complex component 4 1.18424
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 1.18259
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.18259
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.18259
GSR glutathione reductase 1.18226
MAP2K6 mitogen-activated protein kinase kinase 6 1.18193
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.18126
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 1.18093
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.17959
FABP3 fatty acid binding protein 3, muscle and heart 1.17728
CD151 CD151 molecule (Raph blood group) 1.17629
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 1.17629
ACO2 aconitase 2, mitochondrial 1.17497
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 1.17497
PLAU plasminogen activator, urokinase 1.17431
IL13 interleukin 13 1.17431
MGLL monoglyceride lipase 1.173
ETFDH electron-transferring-flavoprotein dehydrogenase 1.17202
CD52 CD52 molecule 1.17168
VLDLR very low density lipoprotein receptor 1.17067
KIF20A kinesin family member 20A 1.17067
DHCR24 24-dehydrocholesterol reductase 1.17067
TNC tenascin C 1.16833
CDKN3 cyclin-dependent kinase inhibitor 3 1.16833
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.16833
SLCO3A1 solute carrier organic anion transporter family, member 3A1 1.16733
GHR growth hormone receptor 1.166
PLK2 polo-like kinase 2 1.16401
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.16368
ADAM9 ADAM metallopeptidase domain 9 1.16335
STX3 syntaxin 3 1.16335
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.16335
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1.16203
IGFBP3 insulin-like growth factor binding protein 3 1.16203
RXRA retinoid X receptor, alpha 1.1607
KDR kinase insert domain receptor 1.1607
HNF4A hepatocyte nuclear factor 4, alpha 1.15967
HDAC1 histone deacetylase 1 1.15967
COTL1 coactosin-like F-actin binding protein 1 1.15933
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 1.15899
BIRC3 baculoviral IAP repeat containing 3 1.15797
KLF4 Kruppel-like factor 4 (gut) 1.15763
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 1.15763
GCG glucagon 1.15763
BHLHE40 basic helix-loop-helix family, member e40 1.15763
APOA4 apolipoprotein A-IV 1.1556
TSC22D3 TSC22 domain family, member 3 1.15526
BMP1 bone morphogenetic protein 1 1.15526
GSTM2 glutathione S-transferase mu 2 (muscle) 1.15156
PRKCA protein kinase C, alpha 1.15156
SOX11 SRY (sex determining region Y)-box 11 1.15122
GSTT1 glutathione S-transferase theta 1 1.14919
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.14919
CH25H cholesterol 25-hydroxylase 1.14747
FSHB follicle stimulating hormone, beta polypeptide 1.14541
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.14507
HIST2H2BE histone cluster 2, H2be 1.1437
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 1.14336
CDCA7 cell division cycle associated 7 1.14336
THRA thyroid hormone receptor, alpha 1.14302
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.14098
ACTN1 actinin, alpha 1 1.1403
SUCLG1 succinate-CoA ligase, alpha subunit 1.13997
SORBS1 sorbin and SH3 domain containing 1 1.13997
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.13997
CBR1 carbonyl reductase 1 1.13929
INHBA inhibin, beta A 1.13689
RBPMS RNA binding protein with multiple splicing 1.13621
PCDH7 protocadherin 7 1.13586
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.13586
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.13518
BGLAP bone gamma-carboxyglutamate (gla) protein 1.13518
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 1.13279
H2AFX H2A histone family, member X 1.13279
PTEN phosphatase and tensin homolog 1.13279
TOP2A topoisomerase (DNA) II alpha 170kDa 1.13279
SPON1 spondin 1, extracellular matrix protein 1.13245
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 1.13245
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.13143
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.13143
PDIA3 protein disulfide isomerase family A, member 3 1.13143
AQP3 aquaporin 3 (Gill blood group) 1.13109
NAPSA napsin A aspartic peptidase 1.13007
OAT ornithine aminotransferase 1.1294
DIO3 deiodinase, iodothyronine, type III 1.12906
RHOC ras homolog family member C 1.12906
DCXR dicarbonyl/L-xylulose reductase 1.12872
FGFR2 fibroblast growth factor receptor 2 1.12737
BMP4 bone morphogenetic protein 4 1.12737
SOD3 superoxide dismutase 3, extracellular 1.12737
LOXL2 lysyl oxidase-like 2 1.12564
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 1.1253
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.1253
PDLIM7 PDZ and LIM domain 7 (enigma) 1.1253
NPPA natriuretic peptide A 1.12461
SQLE squalene epoxidase 1.12357
FGF2 fibroblast growth factor 2 (basic) 1.12323
GSTM1 glutathione S-transferase mu 1 1.12323
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 1.12254
TDO2 tryptophan 2,3-dioxygenase 1.12219
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 1.12185
IRF1 interferon regulatory factor 1 1.12185
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.12151
KLF6 Kruppel-like factor 6 1.12014
GADD45G growth arrest and DNA-damage-inducible, gamma 1.1198
IGFBP5 insulin-like growth factor binding protein 5 1.1198
RARB retinoic acid receptor, beta 1.11843
IFITM1 interferon induced transmembrane protein 1 1.11843
PPL periplakin 1.11571
MDK midkine (neurite growth-promoting factor 2) 1.11536
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 1.11536
CES2 carboxylesterase 2 1.11466
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.11431
PTTG1IP pituitary tumor-transforming 1 interacting protein 1.11396
RPS6 ribosomal protein S6 1.1129
MAP1B microtubule-associated protein 1B 1.1122
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.11186
PLK4 polo-like kinase 4 1.11186
GRB10 growth factor receptor-bound protein 10 1.11186
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.11186
ADIPOQ adiponectin, C1Q and collagen domain containing 1.11081
GTSE1 G-2 and S-phase expressed 1 1.10872
STAR steroidogenic acute regulatory protein 1.10838
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.10803
PDGFB platelet-derived growth factor beta polypeptide 1.10734
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.10734
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.10734
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.10734
FAM101B family with sequence similarity 101, member B 1.10596
PCSK9 proprotein convertase subtilisin/kexin type 9 1.10596
FBLN1 fibulin 1 1.10562
C10ORF10 chromosome 10 open reading frame 10 1.10562
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.10388
CD40 CD40 molecule, TNF receptor superfamily member 5 1.10388
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.10282
SFRP2 secreted frizzled-related protein 2 1.10211
GLUL glutamate-ammonia ligase 1.10211
IL2 interleukin 2 1.10104
TIMP3 TIMP metallopeptidase inhibitor 3 1.10033
IL15RA interleukin 15 receptor, alpha 1.09998
HSPA1A heat shock 70kDa protein 1A 1.09963
MCAM melanoma cell adhesion molecule 1.09927
HSPB1 heat shock 27kDa protein 1 1.09857
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.09857
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.09716
EPO erythropoietin 1.09681
GPX2 glutathione peroxidase 2 1.09681
SMAD3 SMAD family member 3 1.09681
MTTP microsomal triglyceride transfer protein 1.09646
ELN elastin 1.09646
ANGPT1 angiopoietin 1 1.09611
CDT1 chromatin licensing and DNA replication factor 1 1.09611
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 1.09611
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.09611
BBC3 BCL2 binding component 3 1.09506
ADM adrenomedullin 1.09332
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.09332
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.09332
GEM GTP binding protein overexpressed in skeletal muscle 1.09297
SLC39A8 solute carrier family 39 (zinc transporter), member 8 1.09262
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 1.09262
SFTPB surfactant protein B 1.09262
CYBB cytochrome b-245, beta polypeptide 1.0919
IL23A interleukin 23, alpha subunit p19 1.09047
TGFA transforming growth factor, alpha 1.09011
MVP major vault protein 1.08975
IL33 interleukin 33 1.08975
DUSP6 dual specificity phosphatase 6 1.08833
TGM2 transglutaminase 2 1.0869
TLR2 toll-like receptor 2 1.0869
MAP2K3 mitogen-activated protein kinase kinase 3 1.08407
TNNI3 troponin I type 3 (cardiac) 1.08372
HIST1H1C histone cluster 1, H1c 1.08372
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 1.08372
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.08337
IER3 immediate early response 3 1.08196
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.08055
IGF2 insulin-like growth factor 2 1.07875
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.07875
TXNIP thioredoxin interacting protein 1.0784
FGF9 fibroblast growth factor 9 1.07804
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.07804
ACOX1 acyl-CoA oxidase 1, palmitoyl 1.07553
PHLDA2 pleckstrin homology-like domain, family A, member 2 1.07482
ATF5 activating transcription factor 5 1.07482
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 1.07482
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.0734
SLCO2B1 solute carrier organic anion transporter family, member 2B1 1.07305
COL3A1 collagen, type III, alpha 1 1.07234
HLA-DRA major histocompatibility complex, class II, DR alpha 1.07199
SLCO4C1 solute carrier organic anion transporter family, member 4C1 1.07199
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 1.06987
ITGB4 integrin, beta 4 1.06987
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.06952
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 1.06734
EGR3 early growth response 3 1.06698
HSPA4L heat shock 70kDa protein 4-like 1.06661
LPIN1 lipin 1 1.06661
WNT5A wingless-type MMTV integration site family, member 5A 1.06661
SP110 SP110 nuclear body protein 1.06552
PDZRN3 PDZ domain containing ring finger 3 1.06552
SOCS3 suppressor of cytokine signaling 3 1.06479
NDRG2 NDRG family member 2 1.0637
NCF1 neutrophil cytosolic factor 1 1.06152
AREG amphiregulin 1.06152
POU5F1 POU class 5 homeobox 1 1.06152
TGIF1 TGFB-induced factor homeobox 1 1.06116
TBX3 T-box 3 1.06116
CRYAB crystallin, alpha B 1.05972
NUPR1 nuclear protein, transcriptional regulator, 1 1.05972
ECHDC2 enoyl CoA hydratase domain containing 2 1.05936
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 1.059
RPSA ribosomal protein SA 1.059
CLDN4 claudin 4 1.059
CD40LG CD40 ligand 1.059
MCM7 minichromosome maintenance complex component 7 1.05864
MMP13 matrix metallopeptidase 13 1.05828
ALOX5AP arachidonate 5-lipoxygenase-activating protein 1.05648
LHCGR luteinizing hormone/choriogonadotropin receptor 1.05648
STAT5A signal transducer and activator of transcription 5A 1.0561
LBP lipopolysaccharide binding protein 1.0561
PER1 period circadian clock 1 1.0561
LCAT lecithin-cholesterol acyltransferase 1.0561
ENO1 enolase 1, (alpha) 1.05535
PRC1 protein regulator of cytokinesis 1 1.05349
CAPN6 calpain 6 1.05349
PDCL3 phosducin-like 3 1.05312
MTFR1 mitochondrial fission regulator 1 1.05312
IGFBP6 insulin-like growth factor binding protein 6 1.05312
CREB1 cAMP responsive element binding protein 1 1.05163
RETN resistin 1.05089
COL18A1 collagen, type XVIII, alpha 1 1.05052
FBN1 fibrillin 1 1.05052
GBP2 guanylate binding protein 2, interferon-inducible 1.05052
GSTM3 glutathione S-transferase mu 3 (brain) 1.04941
SP1 Sp1 transcription factor 1.04941
SESN1 sestrin 1 1.04831
CCNF cyclin F 1.04831
RGN regucalcin 1.04794
HNF1B HNF1 homeobox B 1.04794
TINAGL1 tubulointerstitial nephritis antigen-like 1 1.04757
WLS wntless Wnt ligand secretion mediator 1.04721
PLBD1 phospholipase B domain containing 1 1.04721
ACTB actin, beta 1.04647
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.04574
MYB v-myb avian myeloblastosis viral oncogene homolog 1.04574
PARP1 poly (ADP-ribose) polymerase 1 1.04538
NEFM neurofilament, medium polypeptide 1.04538
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.04389
TUBB tubulin, beta class I 1.04352
CD2AP CD2-associated protein 1.04314
DAPK2 death-associated protein kinase 2 1.04239
LARP6 La ribonucleoprotein domain family, member 6 1.04201
DEPTOR DEP domain containing MTOR-interacting protein 1.04201
LIPC lipase, hepatic 1.04088
WEE1 WEE1 G2 checkpoint kinase 1.04051
DDIT4 DNA-damage-inducible transcript 4 1.03901
SMAD7 SMAD family member 7 1.03789
CFB complement factor B 1.03789
LMNB1 lamin B1 1.03789
ECI2 enoyl-CoA delta isomerase 2 1.03678
COL13A1 collagen, type XIII, alpha 1 1.03641
FAM198B family with sequence similarity 198, member B 1.03641
GPC4 glypican 4 1.03641
NIT1 nitrilase 1 1.03641
PLEKHA5 pleckstrin homology domain containing, family A member 5 1.03604
RAD50 RAD50 homolog (S. cerevisiae) 1.0353
ARC activity-regulated cytoskeleton-associated protein 1.0353
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.0353
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.0353
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.03345
RXRG retinoid X receptor, gamma 1.03345
KLF5 Kruppel-like factor 5 (intestinal) 1.03308
ESR1 estrogen receptor 1 1.03271
NELL2 NEL-like 2 (chicken) 1.03122
TMOD1 tropomodulin 1 1.03084
TUBA1A tubulin, alpha 1a 1.03084
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 1.03046
PDIA6 protein disulfide isomerase family A, member 6 1.03046
MME membrane metallo-endopeptidase 1.03009
CXCL12 chemokine (C-X-C motif) ligand 12 1.02933
CPT1B carnitine palmitoyltransferase 1B (muscle) 1.02858
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 1.02783
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 1.02634
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 1.02596
ABHD1 abhydrolase domain containing 1 1.02596
CDC25A cell division cycle 25A 1.02596
RGS17 regulator of G-protein signaling 17 1.02559
WNT5B wingless-type MMTV integration site family, member 5B 1.02559
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.02559
RPS14 ribosomal protein S14 1.02559
GJA5 gap junction protein, alpha 5, 40kDa 1.02559
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.02336
PTK2B protein tyrosine kinase 2 beta 1.02336
GDNF glial cell derived neurotrophic factor 1.02336
IL33R interleukin 33 receptor 1.02336
GFAP glial fibrillary acidic protein 1.02262
VASN vasorin 1.02151
GRIK2 glutamate receptor, ionotropic, kainate 2 1.02151
CKS2 CDC28 protein kinase regulatory subunit 2 1.02114
ACO1 aconitase 1, soluble 1.02114
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.02077
FRMD6 FERM domain containing 6 1.02077
CCAR1 cell division cycle and apoptosis regulator 1 1.02077
MMP16 matrix metallopeptidase 16 (membrane-inserted) 1.0204
INHBE inhibin, beta E 1.01928
SESN2 sestrin 2 1.0189
TYMS thymidylate synthetase 1.01739
PKLR pyruvate kinase, liver and RBC 1.01701
SLC30A1 solute carrier family 30 (zinc transporter), member 1 1.01663
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.01625
LPCAT3 lysophosphatidylcholine acyltransferase 3 1.01625
NUSAP1 nucleolar and spindle associated protein 1 1.01625
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 1.01625
NPTX2 neuronal pentraxin II 1.01587
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 1.01587
EPHA4 EPH receptor A4 1.01587
NOS1 nitric oxide synthase 1 (neuronal) 1.01587
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1.01549
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.01437
IL10 interleukin 10 1.01399
MMP12 matrix metallopeptidase 12 1.01399
MT1A metallothionein 1A 1.01324
LY6D lymphocyte antigen 6 complex, locus D 1.01286
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.01249
CD38 CD38 molecule 1.01212
PDYN prodynorphin 1.01174
MT3 metallothionein 3 1.01174
NPAS2 neuronal PAS domain protein 2 1.01174
FXYD1 FXYD domain containing ion transport regulator 1 1.01174
CDCA7L cell division cycle associated 7-like 1.01137
TDRD7 tudor domain containing 7 1.01099
CNTN1 contactin 1 1.01099
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 1.01062