Myositis Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description An inflammatory process affecting the skeletal muscles. Causes include infections, injuries, and autoimmune disorders.|Inflammation of a muscle or muscle tissue. (Experimental Factor Ontology, EFO_0000783)
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Genes

137 genes associated with the disease Myositis in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 2.017
LST1 leukocyte specific transcript 1 2.017
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 2.017
NCR3 natural cytotoxicity triggering receptor 3 2.017
LTB lymphotoxin beta (TNF superfamily, member 3) 2.017
LTA lymphotoxin alpha 2.017
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 2.017
MICB MHC class I polypeptide-related sequence B 2.017
TNF tumor necrosis factor 2.017
MCCD1 mitochondrial coiled-coil domain 1 2.017
STAT4 signal transducer and activator of transcription 4 1.995
STAT1 signal transducer and activator of transcription 1, 91kDa 1.995
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1.992
RSBN1 round spermatid basic protein 1 1.992
KCP kielin/chordin-like protein 1.991
TNPO3 transportin 3 1.991
IRF5 interferon regulatory factor 5 1.991
DCLRE1B DNA cross-link repair 1B 1.981
AP4B1 adaptor-related protein complex 4, beta 1 subunit 1.981
BCL2L15 BCL2-like 15 1.981
HIPK1 homeodomain interacting protein kinase 1 1.981
BTNL2 butyrophilin-like 2 1.968
TSBP1 testis expressed basic protein 1 1.968
HLA-DRA major histocompatibility complex, class II, DR alpha 1.968
CDK6 cyclin-dependent kinase 6 1.948
AIF1 allograft inflammatory factor 1 1.947
BAG6 BCL2-associated athanogene 6 1.947
PRRC2A proline-rich coiled-coil 2A 1.947
HLA-B major histocompatibility complex, class I, B 1.946
PHTF1 putative homeodomain transcription factor 1 1.927
FLNC filamin C, gamma 1.721
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 1.721
RGL1 ral guanine nucleotide dissociation stimulator-like 1 1.655
NCF2 neutrophil cytosolic factor 2 1.655
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1.655
SMG7 SMG7 nonsense mediated mRNA decay factor 1.655
APOBEC4 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) 1.655
ATG5 autophagy related 5 1.471
PRDM1 PR domain containing 1, with ZNF domain 1.471
C1QTNF2 C1q and tumor necrosis factor related protein 2 1.462
PTTG1 pituitary tumor-transforming 1 1.462
SLU7 SLU7 splicing factor homolog (S. cerevisiae) 1.462
ANXA6 annexin A6 1.433
GPX3 glutathione peroxidase 3 1.433
TNIP1 TNFAIP3 interacting protein 1 1.433
SDK1 sidekick cell adhesion molecule 1 1.431
SSMEM1 serine-rich single-pass membrane protein 1 1.395
KLHDC10 kelch domain containing 10 1.395
TMEM209 transmembrane protein 209 1.395
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 1.386
IL23R interleukin 23 receptor 1.365
SERBP1 SERPINE1 mRNA binding protein 1 1.365
IL12RB2 interleukin 12 receptor, beta 2 1.365
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 1.36
PDE4A phosphodiesterase 4A, cAMP-specific 1.294
ICAM3 intercellular adhesion molecule 3 1.294
MRPL4 mitochondrial ribosomal protein L4 1.294
TYK2 tyrosine kinase 2 1.294
RAVER1 ribonucleoprotein, PTB-binding 1 1.294
CDC37 cell division cycle 37 1.294
ZGLP1 zinc finger, GATA-like protein 1 1.294
ICAM5 intercellular adhesion molecule 5, telencephalin 1.294
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 1.294
ICAM1 intercellular adhesion molecule 1 1.294
FDX2 ferredoxin 2 1.294
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 1.274
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.248
HLA-DOA major histocompatibility complex, class II, DO alpha 1.248
BRD2 bromodomain containing 2 1.248
COL11A2 collagen, type XI, alpha 2 1.248
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.248
BLK BLK proto-oncogene, Src family tyrosine kinase 1.156
FAM167A family with sequence similarity 167, member A 1.156
WDFY4 WDFY family member 4 1.129
LRRC18 leucine rich repeat containing 18 1.129
FLNB filamin B, beta 1.127
OLFML3 olfactomedin-like 3 1.127
DNASE1L3 deoxyribonuclease I-like 3 1.127
ABHD6 abhydrolase domain containing 6 1.127
TMEM175 transmembrane protein 175 1.074
RNF212 ring finger protein 212 1.074
GAK cyclin G associated kinase 1.074
DGKQ diacylglycerol kinase, theta 110kDa 1.074
SLC26A1 solute carrier family 26 (anion exchanger), member 1 1.074
IDUA iduronidase, alpha-L- 1.074
FGFRL1 fibroblast growth factor receptor-like 1 1.074
LRP5 low density lipoprotein receptor-related protein 5 1.059
C11ORF24 chromosome 11 open reading frame 24 1.059
PPP6R3 protein phosphatase 6, regulatory subunit 3 1.059
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.058
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 1.001
PRR12 proline rich 12 1.001
IRF3 interferon regulatory factor 3 1.001
ADM5 adrenomedullin 5 (putative) 1.001
SCAF1 SR-related CTD-associated factor 1 1.001
RRAS related RAS viral (r-ras) oncogene homolog 1.001
CPT1C carnitine palmitoyltransferase 1C 1.001
NOSIP nitric oxide synthase interacting protein 1.001
RCN3 reticulocalbin 3, EF-hand calcium binding domain 1.001
BCL2L12 BCL2-like 12 (proline rich) 1.001
PRMT1 protein arginine methyltransferase 1 1.001
FCGRT Fc fragment of IgG, receptor, transporter, alpha 1.001
RPH3A rabphilin 3A 0.963
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.963
RPL6 ribosomal protein L6 0.963
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.963
YPEL1 yippee-like 1 (Drosophila) 0.915
SDF2L1 stromal cell-derived factor 2-like 1 0.915
YDJC YdjC homolog (bacterial) 0.915
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 0.915
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.915
CCDC116 coiled-coil domain containing 116 0.915
RIMBP3C RIMS binding protein 3C 0.915
CDHR5 cadherin-related family member 5 0.654
LMNTD2 lamin tail domain containing 2 0.654
DRD4 dopamine receptor D4 0.654
SCT secretin 0.654
NEMP2 nuclear envelope integral membrane protein 2 0.654
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 0.654
LRRC56 leucine rich repeat containing 56 0.654
GLS glutaminase 0.654
DEAF1 DEAF1 transcription factor 0.654
HRAS Harvey rat sarcoma viral oncogene homolog 0.654
PHRF1 PHD and ring finger domains 1 0.654
TMEM80 transmembrane protein 80 0.654
EPS8L2 EPS8-like 2 0.654
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.654
IRF7 interferon regulatory factor 7 0.654
EIF4H eukaryotic translation initiation factor 4H 0.608
LIMK1 LIM domain kinase 1 0.608
ELN elastin 0.608
LAT2 linker for activation of T cells family, member 2 0.608
IRF8 interferon regulatory factor 8 0.581
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.56
ARL14 ADP-ribosylation factor-like 14 0.56
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.522
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 0.511