Myxedema Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_11634)
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Genes

95 genes co-occuring with the disease Myxedema in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
TSHR thyroid stimulating hormone receptor 2.93
TG thyroglobulin 2.879
TPO thyroid peroxidase 2.58
AVP arginine vasopressin 2.066
POMC proopiomelanocortin 1.96
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 1.949
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.881
TRH thyrotropin-releasing hormone 1.857
ALB albumin 1.797
DIO2 deiodinase, iodothyronine, type II 1.784
INS insulin 1.781
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.728
CKMT1B creatine kinase, mitochondrial 1B 1.727
CKB creatine kinase, brain 1.724
CKM creatine kinase, muscle 1.723
TSHB thyroid stimulating hormone, beta 1.706
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 1.698
THRB thyroid hormone receptor, beta 1.589
IGF1 insulin-like growth factor 1 (somatomedin C) 1.587
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.574
PTH parathyroid hormone 1.534
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 1.53
PRL prolactin 1.526
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.512
IGF1R insulin-like growth factor 1 receptor 1.497
ACOT8 acyl-CoA thioesterase 8 1.49
CKMT1A creatine kinase, mitochondrial 1A 1.465
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1.46
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.447
AIRE autoimmune regulator 1.434
CRP C-reactive protein, pentraxin-related 1.417
REN renin 1.402
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10 1.387
CD4 CD4 molecule 1.324
SLC26A4 solute carrier family 26 (anion exchanger), member 4 1.311
PXDNL peroxidasin-like 1.298
PXDN peroxidasin 1.296
DIO1 deiodinase, iodothyronine, type I 1.29
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1 1.281
THRA thyroid hormone receptor, alpha 1.261
NPPA natriuretic peptide A 1.251
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 1.247
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.247
LDHAL6A lactate dehydrogenase A-like 6A 1.22
CD40 CD40 molecule, TNF receptor superfamily member 5 1.22
ENO1 enolase 1, (alpha) 1.212
ATP5PO ATP synthase peripheral stalk subunit OSCP 1.21
ACE angiotensin I converting enzyme 1.207
TNF tumor necrosis factor 1.206
SLC30A10 solute carrier family 30, member 10 1.2
PDCD1 programmed cell death 1 1.199
LDHAL6B lactate dehydrogenase A-like 6B 1.194
F2 coagulation factor II (thrombin) 1.187
IL6 interleukin 6 1.18
FCRL3 Fc receptor-like 3 1.171
IL16 interleukin 16 1.159
TTR transthyretin 1.153
CRH corticotropin releasing hormone 1.146
CD8A CD8a molecule 1.145
TXNRD2 thioredoxin reductase 2 1.134
IFNA16 interferon, alpha 16 1.122
IFNA14 interferon, alpha 14 1.121
IFNA7 interferon, alpha 7 1.121
TSGA10IP testis specific, 10 interacting protein 1.121
IFNA10 interferon, alpha 10 1.121
IFNA21 interferon, alpha 21 1.121
IFNA8 interferon, alpha 8 1.12
IFNA6 interferon, alpha 6 1.12
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 1.119
IFNA5 interferon, alpha 5 1.119
IFNA13 interferon, alpha 13 1.118
IFNA4 interferon, alpha 4 1.115
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.111
MYH14 myosin, heavy chain 14, non-muscle 1.107
LDHC lactate dehydrogenase C 1.106
IFNA1 interferon, alpha 1 1.105
IFNG interferon, gamma 1.101
IFNA17 interferon, alpha 17 1.092
IL2 interleukin 2 1.09
VWF von Willebrand factor 1.082
AQP2 aquaporin 2 (collecting duct) 1.075
IFNA2 interferon, alpha 2 1.071
NPPB natriuretic peptide B 1.067
TOR1A torsin family 1, member A (torsin A) 1.058
ELP6 elongator acetyltransferase complex subunit 6 1.058
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.05
ECM1 extracellular matrix protein 1 1.046
LHCGR luteinizing hormone/choriogonadotropin receptor 1.044
MB myoglobin 1.038
GCG glucagon 1.035
F3 coagulation factor III (thromboplastin, tissue factor) 1.023
IL1B interleukin 1, beta 1.021
CD274 CD274 molecule 1.009
AVPR2 arginine vasopressin receptor 2 1.007
HAS2 hyaluronan synthase 2 1.001