N-Myc Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog|This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] (NCBI Entrez Gene Database, 4613)
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Genes

9 target genes of the N-Myc transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ASPHD1 aspartate beta-hydroxylase domain containing 1
CLK2 CDC-like kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
G6PC3 glucose 6 phosphatase, catalytic, 3
GADD45G growth arrest and DNA-damage-inducible, gamma
NOP56 NOP56 ribonucleoprotein
PCBP1 poly(rC) binding protein 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD)