N-acetyl-L-aspartic acid-4125 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the N-acetyl-L-aspartic acid-4125 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ADD2 adducin 2 (beta)
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AMELY amelogenin, Y-linked
ANK1 ankyrin 1, erythrocytic
AQP3 aquaporin 3 (Gill blood group)
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATXN2L ataxin 2-like
C18ORF25 chromosome 18 open reading frame 25
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CDO1 cysteine dioxygenase type 1
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP41 centrosomal protein 41kDa
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLCN6 chloride channel, voltage-sensitive 6
COL13A1 collagen, type XIII, alpha 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL7A1 collagen, type VII, alpha 1
CRY2 cryptochrome circadian clock 2
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCC DCC netrin 1 receptor
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DLK2 delta-like 2 homolog (Drosophila)
DSC3 desmocollin 3
DYM dymeclin
EPHB2 EPH receptor B2
ETV5 ets variant 5
FCAR Fc fragment of IgA receptor
FGFR3 fibroblast growth factor receptor 3
GAS7 growth arrest-specific 7
GFAP glial fibrillary acidic protein
GIF gastric intrinsic factor (vitamin B synthesis)
GK glycerol kinase
GK2 glycerol kinase 2
GVINP1 GTPase, very large interferon inducible pseudogene 1
HR hair growth associated
HRASLS HRAS-like suppressor
ICA1 islet cell autoantigen 1, 69kDa
IL1RAP interleukin 1 receptor accessory protein
INHBC inhibin, beta C
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIAA1024 KIAA1024
KIAA1107 KIAA1107
KRT75 keratin 75, type II
LIMCH1 LIM and calponin homology domains 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPCAT4 lysophosphatidylcholine acyltransferase 4
MALL mal, T-cell differentiation protein-like
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MAST3 microtubule associated serine/threonine kinase 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MN1 meningioma (disrupted in balanced translocation) 1
MOBP myelin-associated oligodendrocyte basic protein
MX1 MX dynamin-like GTPase 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCKIPSD NCK interacting protein with SH3 domain
NDRG2 NDRG family member 2
NF2 neurofibromin 2 (merlin)
NOL10 nucleolar protein 10
OPCML opioid binding protein/cell adhesion molecule-like
PLXNC1 plexin C1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PRPH2 peripherin 2 (retinal degeneration, slow)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGS10 regulator of G-protein signaling 10
RIN1 Ras and Rab interactor 1
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPL35A ribosomal protein L35a
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RSU1 Ras suppressor protein 1
SASH3 SAM and SH3 domain containing 3
SERHL2 serine hydrolase-like 2
SH3BP2 SH3-domain binding protein 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SKAP1 src kinase associated phosphoprotein 1
SLAMF7 SLAM family member 7
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTA1 spectrin, alpha, erythrocytic 1
SQSTM1 sequestosome 1
SRD5A3 steroid 5 alpha-reductase 3
SSPN sarcospan
SULT4A1 sulfotransferase family 4A, member 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SVIL supervillin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THEMIS2 thymocyte selection associated family member 2
TLR2 toll-like receptor 2
TMOD1 tropomodulin 1
TUBB2B tubulin, beta 2B class IIb
TUBBP5 tubulin, beta pseudogene 5
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABLIM3 actin binding LIM protein family, member 3
ACTL8 actin-like 8
ADGRG2 adhesion G protein-coupled receptor G2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BAHCC1 BAH domain and coiled-coil containing 1
BCL9 B-cell CLL/lymphoma 9
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C19ORF73 chromosome 19 open reading frame 73
C5AR1 complement component 5a receptor 1
CCDC69 coiled-coil domain containing 69
CD82 CD82 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CENPO centromere protein O
CFHR4 complement factor H-related 4
CIC capicua transcriptional repressor
CLCN5 chloride channel, voltage-sensitive 5
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CUZD1 CUB and zona pellucida-like domains 1
DAGLA diacylglycerol lipase, alpha
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DYSF dysferlin
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM131A family with sequence similarity 131, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL6 F-box and leucine-rich repeat protein 6
FEM1C fem-1 homolog c (C. elegans)
FKBP14 FK506 binding protein 14, 22 kDa
FMOD fibromodulin
FRK fyn-related Src family tyrosine kinase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GOLGA8B golgin A8 family, member B
GUSBP3 glucuronidase, beta pseudogene 3
HCFC1 host cell factor C1
HIST1H1D histone cluster 1, H1d
HIST1H3E histone cluster 1, H3e
HOXB2 homeobox B2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IRF6 interferon regulatory factor 6
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCTD7 potassium channel tetramerization domain containing 7
KLF2 Kruppel-like factor 2
KLF3 Kruppel-like factor 3 (basic)
KRT13 keratin 13, type I
LMNB2 lamin B2
NPR3 natriuretic peptide receptor 3
OSGIN1 oxidative stress induced growth inhibitor 1
PARD6A par-6 family cell polarity regulator alpha
PDE12 phosphodiesterase 12
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNA3 plexin A3
POU4F2 POU class 4 homeobox 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PROL1 proline rich, lacrimal 1
PRR14L proline rich 14-like
R3HCC1L R3H domain and coiled-coil containing 1-like
RGS20 regulator of G-protein signaling 20
RHOBTB2 Rho-related BTB domain containing 2
RNF122 ring finger protein 122
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RUSC2 RUN and SH3 domain containing 2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SGK2 serum/glucocorticoid regulated kinase 2
SLC35F5 solute carrier family 35, member F5
SPAG4 sperm associated antigen 4
SPRR1B small proline-rich protein 1B
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD3 StAR-related lipid transfer (START) domain containing 3
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TEP1 telomerase-associated protein 1
TMEM53 transmembrane protein 53
TNS2 tensin 2
TRIM16 tripartite motif containing 16
TSNAXIP1 translin-associated factor X interacting protein 1
TYRP1 tyrosinase-related protein 1
UCN urocortin
USB1 U6 snRNA biogenesis 1
USP36 ubiquitin specific peptidase 36
VEGFB vascular endothelial growth factor B
VPS9D1 VPS9 domain containing 1
XYLT1 xylosyltransferase I
ZNF551 zinc finger protein 551
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669