| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the N-acetyl-L-leucine-3085 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ACRV1 | acrosomal vesicle protein 1 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOE | apolipoprotein E |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| CACTIN | cactin, spliceosome C complex subunit |
| CCR9 | chemokine (C-C motif) receptor 9 |
| CD1E | CD1e molecule |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFAP70 | cilia and flagella associated protein 70 |
| CLDN3 | claudin 3 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| COL7A1 | collagen, type VII, alpha 1 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) |
| CRX | cone-rod homeobox |
| CRYM | crystallin, mu |
| CSNK1E | casein kinase 1, epsilon |
| DLX2 | distal-less homeobox 2 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EPHA1 | EPH receptor A1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FGF6 | fibroblast growth factor 6 |
| FOXE3 | forkhead box E3 |
| FST | follistatin |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR107 | G protein-coupled receptor 107 |
| HEMK1 | HemK methyltransferase family member 1 |
| HHLA1 | HERV-H LTR-associating 1 |
| HIST1H3G | histone cluster 1, H3g |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 |
| HNF1A | HNF1 homeobox A |
| HOXA2 | homeobox A2 |
| HOXC11 | homeobox C11 |
| HOXD11 | homeobox D11 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFT27 | intraflagellar transport 27 |
| ITGB1BP2 | integrin beta 1 binding protein (melusin) 2 |
| IZUMO4 | IZUMO family member 4 |
| JRK | Jrk homolog (mouse) |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KLHL18 | kelch-like family member 18 |
| LARGE | like-glycosyltransferase |
| LIG3 | ligase III, DNA, ATP-dependent |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 |
| MCHR1 | melanin-concentrating hormone receptor 1 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NEBL | nebulette |
| NFIB | nuclear factor I/B |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NUP50 | nucleoporin 50kDa |
| OMG | oligodendrocyte myelin glycoprotein |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PADI2 | peptidyl arginine deiminase, type II |
| PCDH12 | protocadherin 12 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PLAC4 | placenta-specific 4 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POU2F2 | POU class 2 homeobox 2 |
| POU3F4 | POU class 3 homeobox 4 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PRKCE | protein kinase C, epsilon |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PRPH | peripherin |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SH2D4A | SH2 domain containing 4A |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC6A16 | solute carrier family 6, member 16 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNAI2 | snail family zinc finger 2 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| STK38 | serine/threonine kinase 38 |
| T | T, brachyury homolog (mouse) |
| TDO2 | tryptophan 2,3-dioxygenase |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TNPO3 | transportin 3 |
| TRIM15 | tripartite motif containing 15 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF219 | zinc finger protein 219 |
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| AGBL5 | ATP/GTP binding protein-like 5 |
| AKTIP | AKT interacting protein |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARMC7 | armadillo repeat containing 7 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| BAG4 | BCL2-associated athanogene 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) |
| BTBD2 | BTB (POZ) domain containing 2 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CBR1 | carbonyl reductase 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DEPDC1 | DEP domain containing 1 |
| FAM127B | family with sequence similarity 127, member B |
| FES | FES proto-oncogene, tyrosine kinase |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GRAMD1B | GRAM domain containing 1B |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIRA | histone cell cycle regulator |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4E | histone cluster 1, H4e |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IREB2 | iron-responsive element binding protein 2 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| KPTN | kaptin (actin binding protein) |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| METTL8 | methyltransferase like 8 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MYO5C | myosin VC |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NABP2 | nucleic acid binding protein 2 |
| NAG18 | NAG18 mRNA |
| NDE1 | nudE neurodevelopment protein 1 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDZD7 | PDZ domain containing 7 |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POLM | polymerase (DNA directed), mu |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PRAF2 | PRA1 domain family, member 2 |
| RAB8B | RAB8B, member RAS oncogene family |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF122 | ring finger protein 122 |
| RPA4 | replication protein A4, 30kDa |
| SCRIB | scribbled planar cell polarity protein |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SPAG4 | sperm associated antigen 4 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STEAP3 | STEAP family member 3, metalloreductase |
| STRN | striatin, calmodulin binding protein |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TACO1 | translational activator of mitochondrially encoded cytochrome c oxidase I |
| TBX19 | T-box 19 |
| TESK2 | testis-specific kinase 2 |
| TGM5 | transglutaminase 5 |
| TMEM159 | transmembrane protein 159 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM5 | tripartite motif containing 5 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUFT1 | tuftelin 1 |
| UNKL | unkempt family zinc finger-like |
| USP18 | ubiquitin specific peptidase 18 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WDR46 | WD repeat domain 46 |
| YY2 | YY2 transcription factor |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZMYM3 | zinc finger, MYM-type 3 |
