Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the N-acetyl-L-leucine-5683 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
AEBP1 | AE binding protein 1 |
ALLC | allantoicase |
APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
BIN2 | bridging integrator 2 |
C2ORF72 | chromosome 2 open reading frame 72 |
C6 | complement component 6 |
C8A | complement component 8, alpha polypeptide |
CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
CAMK1D | calcium/calmodulin-dependent protein kinase ID |
CASR | calcium-sensing receptor |
CD209 | CD209 molecule |
CD244 | CD244 molecule, natural killer cell receptor 2B4 |
CD36 | CD36 molecule (thrombospondin receptor) |
CD53 | CD53 molecule |
CHD5 | chromodomain helicase DNA binding protein 5 |
CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
CNTNAP2 | contactin associated protein-like 2 |
COL1A2 | collagen, type I, alpha 2 |
CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
CRHR2 | corticotropin releasing hormone receptor 2 |
DFNB31 | deafness, autosomal recessive 31 |
DGCR8 | DGCR8 microprocessor complex subunit |
DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
DTX3 | deltex 3, E3 ubiquitin ligase |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
FAM63B | family with sequence similarity 63, member B |
FBLN1 | fibulin 1 |
FIGF | c-fos induced growth factor (vascular endothelial growth factor D) |
GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type |
GP5 | glycoprotein V (platelet) |
GPER1 | G protein-coupled estrogen receptor 1 |
GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
GRK4 | G protein-coupled receptor kinase 4 |
GRM1 | glutamate receptor, metabotropic 1 |
GSK3A | glycogen synthase kinase 3 alpha |
GUK1 | guanylate kinase 1 |
HAP1 | huntingtin-associated protein 1 |
HCRT | hypocretin (orexin) neuropeptide precursor |
HES2 | hes family bHLH transcription factor 2 |
HIST1H4E | histone cluster 1, H4e |
HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
IDUA | iduronidase, alpha-L- |
IGF2-AS | IGF2 antisense RNA |
IGFBP5 | insulin-like growth factor binding protein 5 |
IL18 | interleukin 18 |
IL22 | interleukin 22 |
KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
KCTD17 | potassium channel tetramerization domain containing 17 |
KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
KRT6B | keratin 6B, type II |
KRTAP9-9 | keratin associated protein 9-9 |
LDB3 | LIM domain binding 3 |
LY86 | lymphocyte antigen 86 |
MAU2 | MAU2 sister chromatid cohesion factor |
MBD3 | methyl-CpG binding domain protein 3 |
MOXD1 | monooxygenase, DBH-like 1 |
MPO | myeloperoxidase |
NDRG2 | NDRG family member 2 |
NPFF | neuropeptide FF-amide peptide precursor |
NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
OR7C1 | olfactory receptor, family 7, subfamily C, member 1 |
PCDH9 | protocadherin 9 |
PCDHB13 | protocadherin beta 13 |
PDPN | podoplanin |
PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
PLCE1 | phospholipase C, epsilon 1 |
PLP1 | proteolipid protein 1 |
PRDM16 | PR domain containing 16 |
PRKCA | protein kinase C, alpha |
RB1 | retinoblastoma 1 |
RHBG | Rh family, B glycoprotein (gene/pseudogene) |
RIMS2 | regulating synaptic membrane exocytosis 2 |
RS1 | retinoschisin 1 |
SCARF1 | scavenger receptor class F, member 1 |
SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
SLC43A3 | solute carrier family 43, member 3 |
SMG7-AS1 | SMG7 antisense RNA 1 |
SPAG6 | sperm associated antigen 6 |
SPHK2 | sphingosine kinase 2 |
SRCAP | Snf2-related CREBBP activator protein |
STXBP5L | syntaxin binding protein 5-like |
SYT12 | synaptotagmin XII |
TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
TAT | tyrosine aminotransferase |
TBC1D2B | TBC1 domain family, member 2B |
TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
TPSB2 | tryptase beta 2 (gene/pseudogene) |
TRIM3 | tripartite motif containing 3 |
TSPAN12 | tetraspanin 12 |
VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
ZBTB7A | zinc finger and BTB domain containing 7A |
ZFAND5 | zinc finger, AN1-type domain 5 |
ZNF471 | zinc finger protein 471 |
Symbol | Name |
---|---|
ACAD10 | acyl-CoA dehydrogenase family, member 10 |
ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
AFAP1 | actin filament associated protein 1 |
ARL15 | ADP-ribosylation factor-like 15 |
ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
ATP13A2 | ATPase type 13A2 |
AXIN1 | axin 1 |
BCOR | BCL6 corepressor |
BEX4 | brain expressed, X-linked 4 |
BFSP1 | beaded filament structural protein 1, filensin |
BPGM | 2,3-bisphosphoglycerate mutase |
C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
CAMKMT | calmodulin-lysine N-methyltransferase |
CAPN5 | calpain 5 |
CASP3 | caspase 3, apoptosis-related cysteine peptidase |
CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
CDKL3 | cyclin-dependent kinase-like 3 |
CENPQ | centromere protein Q |
CGA | glycoprotein hormones, alpha polypeptide |
CLCN2 | chloride channel, voltage-sensitive 2 |
CLGN | calmegin |
COTL1 | coactosin-like F-actin binding protein 1 |
CTNND2 | catenin (cadherin-associated protein), delta 2 |
DGAT1 | diacylglycerol O-acyltransferase 1 |
ELOVL4 | ELOVL fatty acid elongase 4 |
EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
ERI3 | ERI1 exoribonuclease family member 3 |
FAM169A | family with sequence similarity 169, member A |
FKBP5 | FK506 binding protein 5 |
GBP2 | guanylate binding protein 2, interferon-inducible |
GLI3 | GLI family zinc finger 3 |
GLS2 | glutaminase 2 (liver, mitochondrial) |
GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
GRTP1 | growth hormone regulated TBC protein 1 |
HHLA3 | HERV-H LTR-associating 3 |
HIST1H1D | histone cluster 1, H1d |
HMHA1 | histocompatibility (minor) HA-1 |
HOXD11 | homeobox D11 |
HSPA1L | heat shock 70kDa protein 1-like |
IFI27 | interferon, alpha-inducible protein 27 |
IFI6 | interferon, alpha-inducible protein 6 |
IFT81 | intraflagellar transport 81 |
IPP | intracisternal A particle-promoted polypeptide |
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
KRI1 | KRI1 homolog (S. cerevisiae) |
LAMA3 | laminin, alpha 3 |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
MANBA | mannosidase, beta A, lysosomal |
MAPK12 | mitogen-activated protein kinase 12 |
MBNL3 | muscleblind-like splicing regulator 3 |
MBTD1 | mbt domain containing 1 |
MITF | microphthalmia-associated transcription factor |
MXD3 | MAX dimerization protein 3 |
MYL5 | myosin, light chain 5, regulatory |
MYO1D | myosin ID |
NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
NDE1 | nudE neurodevelopment protein 1 |
NECAB3 | N-terminal EF-hand calcium binding protein 3 |
NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
PDE8B | phosphodiesterase 8B |
PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
POLH | polymerase (DNA directed), eta |
POLL | polymerase (DNA directed), lambda |
POMZP3 | POM121 and ZP3 fusion |
PRAF2 | PRA1 domain family, member 2 |
PRPH | peripherin |
PRSS16 | protease, serine, 16 (thymus) |
PTK6 | protein tyrosine kinase 6 |
PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
PTPRU | protein tyrosine phosphatase, receptor type, U |
RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
S100A9 | S100 calcium binding protein A9 |
SCAMP5 | secretory carrier membrane protein 5 |
SETD8 | SET domain containing (lysine methyltransferase) 8 |
SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
SHARPIN | SHANK-associated RH domain interactor |
SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
SLC41A3 | solute carrier family 41, member 3 |
TDRD1 | tudor domain containing 1 |
TET3 | tet methylcytosine dioxygenase 3 |
THOP1 | thimet oligopeptidase 1 |
TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
TTC33 | tetratricopeptide repeat domain 33 |
USP20 | ubiquitin specific peptidase 20 |
VASP | vasodilator-stimulated phosphoprotein |
VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
ZBED1 | zinc finger, BED-type containing 1 |
ZFHX3 | zinc finger homeobox 3 |
ZFP69B | ZFP69 zinc finger protein B |
ZNF250 | zinc finger protein 250 |
ZNF254 | zinc finger protein 254 |
ZNF324 | zinc finger protein 324 |
ZNF329 | zinc finger protein 329 |