| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the N-acetyl-L-leucine-6462 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY10 | adenylate cyclase 10 (soluble) |
| AIM2 | absent in melanoma 2 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| APOL2 | apolipoprotein L, 2 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ASPH | aspartate beta-hydroxylase |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BCO1 | beta-carotene oxygenase 1 |
| CA1 | carbonic anhydrase I |
| CCDC134 | coiled-coil domain containing 134 |
| CD44 | CD44 molecule (Indian blood group) |
| CD86 | CD86 molecule |
| CD8A | CD8a molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLEC4E | C-type lectin domain family 4, member E |
| CLEC7A | C-type lectin domain family 7, member A |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| COL3A1 | collagen, type III, alpha 1 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FOXP3 | forkhead box P3 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GJB3 | gap junction protein, beta 3, 31kDa |
| HBS1L | HBS1-like translational GTPase |
| HIST1H3F | histone cluster 1, H3f |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IHH | indian hedgehog |
| IL18BP | interleukin 18 binding protein |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIF21B | kinesin family member 21B |
| KIF5A | kinesin family member 5A |
| LEFTY1 | left-right determination factor 1 |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRC23 | leucine rich repeat containing 23 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LRRN2 | leucine rich repeat neuronal 2 |
| LTB4R | leukotriene B4 receptor |
| MAPK10 | mitogen-activated protein kinase 10 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MED14 | mediator complex subunit 14 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| NHLH2 | nescient helix loop helix 2 |
| NKX3-2 | NK3 homeobox 2 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUP188 | nucleoporin 188kDa |
| OCM2 | oncomodulin 2 |
| PAX8 | paired box 8 |
| PCDH1 | protocadherin 1 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PKLR | pyruvate kinase, liver and RBC |
| PLTP | phospholipid transfer protein |
| PLXNB3 | plexin B3 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
| PVR | poliovirus receptor |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RASAL2 | RAS protein activator like 2 |
| RGS11 | regulator of G-protein signaling 11 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RUNX1 | runt-related transcription factor 1 |
| SAA3P | serum amyloid A3 pseudogene |
| SAMD9 | sterile alpha motif domain containing 9 |
| SIRT5 | sirtuin 5 |
| SIX1 | SIX homeobox 1 |
| SLA | Src-like-adaptor |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC5A12 | solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SPAG6 | sperm associated antigen 6 |
| TENM4 | teneurin transmembrane protein 4 |
| TMEM246 | transmembrane protein 246 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSC22D2 | TSC22 domain family, member 2 |
| USP46 | ubiquitin specific peptidase 46 |
| VSNL1 | visinin-like 1 |
| ZNF750 | zinc finger protein 750 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOD | apolipoprotein D |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASPN | asporin |
| BAG4 | BCL2-associated athanogene 4 |
| CA11 | carbonic anhydrase XI |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CAPRIN2 | caprin family member 2 |
| CCDC85C | coiled-coil domain containing 85C |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN17 | claudin 17 |
| CLSPN | claspin |
| CXADR | coxsackie virus and adenovirus receptor |
| CXXC4 | CXXC finger protein 4 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DYSF | dysferlin |
| EGFL7 | EGF-like-domain, multiple 7 |
| FBXO2 | F-box protein 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H4D | histone cluster 1, H4d |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXC5 | homeobox C5 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL15RA | interleukin 15 receptor, alpha |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRF1 | interferon regulatory factor 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC100287590 | uncharacterized LOC100287590 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MCC | mutated in colorectal cancers |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MED31 | mediator complex subunit 31 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXD3 | MAX dimerization protein 3 |
| MYBBP1A | MYB binding protein (P160) 1a |
| NECAP2 | NECAP endocytosis associated 2 |
| NELL2 | NEL-like 2 (chicken) |
| NPTX1 | neuronal pentraxin I |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PADI2 | peptidyl arginine deiminase, type II |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PLD3 | phospholipase D family, member 3 |
| PRDM14 | PR domain containing 14 |
| PRSS22 | protease, serine, 22 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF19B | ring finger protein 19B |
| RNF31 | ring finger protein 31 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SECTM1 | secreted and transmembrane 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SSFA2 | sperm specific antigen 2 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| STK16 | serine/threonine kinase 16 |
| STRA6 | stimulated by retinoic acid 6 |
| SYNC | syncoilin, intermediate filament protein |
| SYNGR3 | synaptogyrin 3 |
| THBS3 | thrombospondin 3 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TLR5 | toll-like receptor 5 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TOM1 | target of myb1 (chicken) |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TTC4 | tetratricopeptide repeat domain 4 |
| UBQLN4 | ubiquilin 4 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| XYLT2 | xylosyltransferase II |
| ZNF365 | zinc finger protein 365 |
| ZNF428 | zinc finger protein 428 |
| ZNF442 | zinc finger protein 442 |
| ZNF492 | zinc finger protein 492 |
| ZNF506 | zinc finger protein 506 |
| ZNF623 | zinc finger protein 623 |
