N-glycan trimming in the ER and Calnexin/Calreticulin cycle Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-532668
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Genes

35 proteins participating in the N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
CALR calreticulin
CANX calnexin
DERL1 derlin 1
DERL2 derlin 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
ENGASE endo-beta-N-acetylglucosaminidase
GANAB glucosidase, alpha; neutral AB
MAN1B1 mannosidase, alpha, class 1B, member 1
MARCHF6 membrane associated ring-CH-type finger 6
MLEC malectin
MOGS mannosyl-oligosaccharide glucosidase
NGLY1 N-glycanase 1
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
PDIA3 protein disulfide isomerase family A, member 3
PRKCSH protein kinase C substrate 80K-H
PSMC1 proteasome (prosome, macropain) 26S subunit, ATPase, 1
RAD23B RAD23 homolog B (S. cerevisiae)
RNF103 ring finger protein 103
RNF139 ring finger protein 139
RNF185 ring finger protein 185
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RPS27A ribosomal protein S27a
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TRIM13 tripartite motif containing 13
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBB ubiquitin B
UBC ubiquitin C
UBXN1 UBX domain protein 1
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VCP valosin containing protein