| Dataset | GO Molecular Function Annotations 2025 |
| Category | structural or functional annotations |
| Type | molecular function |
| Description | Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser. (Gene Ontology, GO_0071885) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0071885 |
| Similar Terms | |
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2 genes performing the N-terminal protein N-methyltransferase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.
