NAAA Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description N-acylethanolamine acid amidase|This gene encodes an N-acylethanolamine-hydrolyzing enzyme which is highly similar to acid ceramidase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 27163)
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Genes

367 genes differentially expressed following the NAAA gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 2.45583
RIMBP2 RIMS binding protein 2 2.45583
IL5RA interleukin 5 receptor, alpha 2.45583
UMOD uromodulin 2.45583
ADTRP androgen-dependent TFPI-regulating protein 2.45583
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 2.45583
PAX7 paired box 7 2.45583
ARHGAP36 Rho GTPase activating protein 36 2.45583
CSMD3 CUB and Sushi multiple domains 3 2.45583
ASB14 ankyrin repeat and SOCS box containing 14 2.45583
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13 2.45583
GPR26 G protein-coupled receptor 26 2.45583
PNMA5 paraneoplastic Ma antigen family member 5 2.45583
SOX14 SRY (sex determining region Y)-box 14 2.45583
VTN vitronectin 2.45583
CHRND cholinergic receptor, nicotinic, delta (muscle) 2.45583
GPR55 G protein-coupled receptor 55 2.45583
OR52H1 olfactory receptor, family 52, subfamily H, member 1 2.45583
CABP4 calcium binding protein 4 2.45583
NANOS2 nanos homolog 2 (Drosophila) 2.45583
SCGB3A1 secretoglobin, family 3A, member 1 2.45583
GLUD2 glutamate dehydrogenase 2 2.45583
ZNF469 zinc finger protein 469 2.45583
TM4SF1 transmembrane 4 L six family member 1 2.45583
HES5 hes family bHLH transcription factor 5 2.45583
TAL1 T-cell acute lymphocytic leukemia 1 2.45583
TCAF2 TRPM8 channel-associated factor 2 2.45583
UNC45B unc-45 homolog B (C. elegans) 2.45583
MYO16 myosin XVI 2.45583
MYO1G myosin IG 2.45583
CPLX4 complexin 4 2.45583
TMC2 transmembrane channel-like 2 2.45583
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 2.45583
ACY3 aminoacylase 3 2.45583
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 2.45583
TDO2 tryptophan 2,3-dioxygenase 2.45583
DEFB105A defensin, beta 105A 2.45583
MYO9B myosin IXB 2.45583
SMCO3 single-pass membrane protein with coiled-coil domains 3 2.45583
BMP3 bone morphogenetic protein 3 2.45583
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 2.45583
ADAMTSL5 ADAMTS-like 5 2.45583
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 2.45583
ACVRL1 activin A receptor type II-like 1 2.45583
SOWAHB sosondowah ankyrin repeat domain family member B 2.45583
S100A1 S100 calcium binding protein A1 2.45583
PNOC prepronociceptin 2.45583
HBZ hemoglobin, zeta 2.45583
CRYGB crystallin, gamma B 2.45583
CRYGA crystallin, gamma A 2.45583
BFSP2 beaded filament structural protein 2, phakinin 2.45583
TAS2R13 taste receptor, type 2, member 13 2.45583
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 2.45583
OR5P3 olfactory receptor, family 5, subfamily P, member 3 2.45583
CPNE8-AS1 CPNE8 antisense RNA 1 2.45583
PLAAT2 phospholipase A and acyltransferase 2 2.45583
SHISAL1 shisa like 1 2.45583
DEPP1 DEPP autophagy regulator 1 2.45583
ESS2 ess-2 splicing factor homolog 2.45583
GOLGA6L7 golgin A6 family like 7 2.45583
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 2.45583
GBP6 guanylate binding protein family, member 6 2.45583
EPCIP exosomal polycystin 1 interacting protein 2.45583
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 2.45583
GPR33 G protein-coupled receptor 33 (gene/pseudogene) 2.45583
STX11 syntaxin 11 2.45583
CBY2 chibby family member 2 2.45583
H3C15 H3 clustered histone 15 2.45583
NOTCH2NLB notch 2 N-terminal like B 2.45583
DEFB109B defensin beta 109B 2.45583
CIMAP1B ciliary microtubule associated protein 1B 2.45583
SERTM2 serine rich and transmembrane domain containing 2 2.45583
CFAP73 cilia and flagella associated protein 73 2.45583
MUCL3 mucin like 3 2.45583
CLEC20A C-type lectin domain containing 20A 2.45583
TUBB8B tubulin beta 8B 2.45583
CPHXL cytoplasmic polyadenylated homeobox like 2.45583
STPG3 sperm-tail PG-rich repeat containing 3 2.45583
SPEM2 SPEM family member 2 2.45583
FMO2 flavin containing monooxygenase 2 (non-functional) 2.45583
BDKRB2 bradykinin receptor B2 2.45583
PELI2 pellino E3 ubiquitin protein ligase family member 2 2.45583
ZIC4 Zic family member 4 2.45583
TMEM235 transmembrane protein 235 2.45583
CATSPER1 cation channel, sperm associated 1 2.45583
CBLN3 cerebellin 3 precursor 2.45583
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.45583
NXPE2 neurexophilin and PC-esterase domain family, member 2 2.45583
ITK IL2-inducible T-cell kinase 2.45583
IRF8 interferon regulatory factor 8 2.45583
CLDN9 claudin 9 2.45583
RLBP1 retinaldehyde binding protein 1 2.45583
GRXCR1 glutaredoxin, cysteine rich 1 2.45583
DMBX1 diencephalon/mesencephalon homeobox 1 2.45583
PRKCE protein kinase C, epsilon 2.45583
SPATA25 spermatogenesis associated 25 2.45583
GCSAM germinal center-associated, signaling and motility 2.45583
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 2.45583
GDF9 growth differentiation factor 9 2.45583
GPR84 G protein-coupled receptor 84 2.45583
BARX2 BARX homeobox 2 2.45583
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.45583
INSRR insulin receptor-related receptor 2.45583
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 2.45583
ESR1 estrogen receptor 1 2.45583
SLC45A2 solute carrier family 45, member 2 2.45583
COL19A1 collagen, type XIX, alpha 1 2.45583
RHOJ ras homolog family member J 2.45583
SHOX short stature homeobox 2.45583
PMP2 peripheral myelin protein 2 2.45583
SLC22A24 solute carrier family 22, member 24 2.45583
PCDHGB2 protocadherin gamma subfamily B, 2 2.45583
DHH desert hedgehog 2.45583
KRTAP5-11 keratin associated protein 5-11 2.45583
SRRM5 serine/arginine repetitive matrix 5 2.45583
NIM1K NIM1 serine/threonine protein kinase 2.45583
HAMP hepcidin antimicrobial peptide 2.45583
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.45583
PLA2G4D phospholipase A2, group IVD (cytosolic) 2.45583
CATIP ciliogenesis associated TTC17 interacting protein 2.45583
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.45583
SAMD5 sterile alpha motif domain containing 5 2.45583
KLK5 kallikrein-related peptidase 5 2.45583
CALML6 calmodulin-like 6 2.45583
FBXO40 F-box protein 40 2.45583
ZMYND15 zinc finger, MYND-type containing 15 2.45583
FCN3 ficolin (collagen/fibrinogen domain containing) 3 2.45583
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 2.45583
DNAH10 dynein, axonemal, heavy chain 10 2.45583
RGSL1 regulator of G-protein signaling like 1 2.45583
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 2.45583
WFDC9 WAP four-disulfide core domain 9 2.45583
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.45583
BAHCC1 BAH domain and coiled-coil containing 1 2.45583
PAGE4 P antigen family, member 4 (prostate associated) 2.45583
CLEC4G C-type lectin domain family 4, member G 2.45583
PCDHGA2 protocadherin gamma subfamily A, 2 2.45583
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 2.45583
TRIM55 tripartite motif containing 55 2.45583
GOLGA6A golgin A6 family, member A 2.45583
KLHL41 kelch-like family member 41 2.45583
FOXE3 forkhead box E3 2.45583
EHF ets homologous factor 2.45583
MUC13 mucin 13, cell surface associated 2.45583
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 2.45583
KLHL6 kelch-like family member 6 2.45583
EVPLL envoplakin-like 2.45583
BTNL8 butyrophilin-like 8 2.45583
DGCR6 DiGeorge syndrome critical region gene 6 2.45583
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 2.45583
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 2.45583
KRTAP13-4 keratin associated protein 13-4 2.45583
TAS2R41 taste receptor, type 2, member 41 2.45583
IL18RAP interleukin 18 receptor accessory protein 2.45583
HEPACAM hepatic and glial cell adhesion molecule 2.45583
ADAM20 ADAM metallopeptidase domain 20 2.45583
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.45583
HCRT hypocretin (orexin) neuropeptide precursor 2.45583
CNGB1 cyclic nucleotide gated channel beta 1 2.45583
TMEM156 transmembrane protein 156 2.45583
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 2.45583
TAS2R46 taste receptor, type 2, member 46 2.45583
ZPBP zona pellucida binding protein 2.45583
R3HDML R3H domain containing-like 2.45583
PHOX2A paired-like homeobox 2a 2.45583
IRX4 iroquois homeobox 4 2.45583
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) 2.45583
NEUROD2 neuronal differentiation 2 2.45583
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 2.45583
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 2.45583
RP1 retinitis pigmentosa 1 (autosomal dominant) 2.45583
DNAH8 dynein, axonemal, heavy chain 8 2.45583
MAGEA12 melanoma antigen family A12 2.45583
CLCNKA chloride channel, voltage-sensitive Ka 2.45583
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.45583
LAMP3 lysosomal-associated membrane protein 3 2.45583
APOL1 apolipoprotein L, 1 2.45583
CHRM1 cholinergic receptor, muscarinic 1 2.45583
ANKRD55 ankyrin repeat domain 55 2.45583
ERP27 endoplasmic reticulum protein 27 2.45583
HLA-DOB major histocompatibility complex, class II, DO beta 2.45583
MC5R melanocortin 5 receptor 2.45583
PGR progesterone receptor 2.45583
RIBC1 RIB43A domain with coiled-coils 1 2.45583
CCDC70 coiled-coil domain containing 70 2.45583
PRAP1 proline-rich acidic protein 1 2.45583
LMX1A LIM homeobox transcription factor 1, alpha 2.45583
WNT10B wingless-type MMTV integration site family, member 10B 2.45583
TM4SF19 transmembrane 4 L six family member 19 2.45583
LAMB4 laminin, beta 4 2.45583
ESPNL espin-like 2.45583
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.45583
C9ORF57 chromosome 9 open reading frame 57 2.45583
PNMA8B PNMA family member 8B 2.43148
DCDC2B doublecortin domain containing 2B 2.4135
WAS Wiskott-Aldrich syndrome 2.40909
AHSG alpha-2-HS-glycoprotein 2.40909
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.40909
CFAP141 cilia and flagella associated protein 141 2.40909
IZUMO2 IZUMO family member 2 2.39598
FZD2 frizzled class receptor 2 2.39598
CDC14B cell division cycle 14B 2.39598
CERT1 ceramide transporter 1 2.35958
PXK PX domain containing serine/threonine kinase 2.33184
IAPP islet amyloid polypeptide 2.33184
KY kyphoscoliosis peptidase 2.33184
CREB3L1 cAMP responsive element binding protein 3-like 1 2.32779
MICOS10 mitochondrial contact site and cristae organizing system subunit 10 2.28625
GLYATL1B glycine-N-acyltransferase like 1B 2.28259
SLC39A7 solute carrier family 39 (zinc transporter), member 7 2.2425
FAM156A family with sequence similarity 156, member A 2.24041
CDHR1 cadherin-related family member 1 2.24032
MYH14 myosin, heavy chain 14, non-muscle 2.24032
DDRGK1 DDRGK domain containing 1 2.22878
APOO apolipoprotein O 2.22353
UBR5 ubiquitin protein ligase E3 component n-recognin 5 2.21813
HARS2 histidyl-tRNA synthetase 2, mitochondrial 2.20916
TMEM52 transmembrane protein 52 2.1979
CCNE2 cyclin E2 2.1979
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 2.19562
GFOD2 glucose-fructose oxidoreductase domain containing 2 2.18959
ACSBG1 acyl-CoA synthetase bubblegum family member 1 2.18445
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 2.18169
PDLIM4 PDZ and LIM domain 4 2.16477
RPL26L1 ribosomal protein L26-like 1 2.13231
PHF23 PHD finger protein 23 2.13069
CEP76 centrosomal protein 76kDa 2.12317
ZBED1 zinc finger, BED-type containing 1 2.10096
RABGAP1L RAB GTPase activating protein 1-like 2.05701
LY6G5B lymphocyte antigen 6 complex, locus G5B 2.04933
H3C8 H3 clustered histone 8 2.04274
CARMIL1 capping protein regulator and myosin 1 linker 1 2.03977
SRGAP2B SLIT-ROBO Rho GTPase activating protein 2B 2.03868
MMP24 matrix metallopeptidase 24 (membrane-inserted) 2.03676
PFKL phosphofructokinase, liver 2.03661
ARL17A ADP-ribosylation factor-like 17A 2.03661
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 2.03491
PLPP7 phospholipid phosphatase 7 (inactive) 2.01744
MGA MGA, MAX dimerization protein 2.01744
FASN fatty acid synthase 2.01466
DHODH dihydroorotate dehydrogenase (quinone) 2.01426
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 2.0142
GRIP1 glutamate receptor interacting protein 1 2.01173
RNF182 ring finger protein 182 2.01173

decreased expression

Symbol Name Standardized Value
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 -2.45583
TMC3 transmembrane channel-like 3 -2.45583
GALR3 galanin receptor 3 -2.45583
ASMT acetylserotonin O-methyltransferase -2.45583
SERF1B small EDRK-rich factor 1B (centromeric) -2.45583
CC2D2B coiled-coil and C2 domain containing 2B -2.45583
PTGES3L prostaglandin E synthase 3 (cytosolic)-like -2.45583
TIAM1 T-cell lymphoma invasion and metastasis 1 -2.45583
ELMO3 engulfment and cell motility 3 -2.45583
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -2.45583
FAM110D family with sequence similarity 110, member D -2.45583
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) -2.45583
PTPN5 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) -2.45583
ADRA1B adrenoceptor alpha 1B -2.45583
SHISA3 shisa family member 3 -2.45583
EPSTI1 epithelial stromal interaction 1 (breast) -2.45583
PLS1 plastin 1 -2.45583
NR4A3 nuclear receptor subfamily 4, group A, member 3 -2.45583
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -2.45583
TPPP tubulin polymerization promoting protein -2.45583
NXPH3 neurexophilin 3 -2.45583
SLC46A2 solute carrier family 46, member 2 -2.45583
HTRA3 HtrA serine peptidase 3 -2.45583
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -2.45583
CCNQ cyclin Q -2.45583
DEFB131B defensin beta 131B -2.45583
CCNP cyclin P -2.45583
STMP1 short transmembrane mitochondrial protein 1 -2.45583
LOC124903233 uncharacterized LOC124903233 -2.45583
CSP2 CS pseudogene 2 -2.45583
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A -2.45583
DUSP8 dual specificity phosphatase 8 -2.45583
LY6H lymphocyte antigen 6 complex, locus H -2.45583
NPPC natriuretic peptide C -2.45583
TBX22 T-box 22 -2.45583
PCDHB11 protocadherin beta 11 -2.45583
CCDC13 coiled-coil domain containing 13 -2.45583
BBS5 Bardet-Biedl syndrome 5 -2.45583
REC114 REC114 meiotic recombination protein -2.45583
XRN2 5'-3' exoribonuclease 2 -2.45583
VSIG10 V-set and immunoglobulin domain containing 10 -2.45583
MAP3K4-AS1 MAP3K4 antisense RNA 1 -2.45583
SGSM3 small G protein signaling modulator 3 -2.45583
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.45583
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -2.45583
TAPBPL TAP binding protein-like -2.45583
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 -2.45583
ZNF221 zinc finger protein 221 -2.45583
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -2.45583
KLF4 Kruppel-like factor 4 (gut) -2.45583
AKNAD1 AKNA domain containing 1 -2.45583
KLK6 kallikrein-related peptidase 6 -2.45583
EGR2 early growth response 2 -2.45583
EMILIN1 elastin microfibril interfacer 1 -2.45583
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.45583
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 -2.45583
CST1 cystatin SN -2.45583
C17ORF107 chromosome 17 open reading frame 107 -2.45583
SYT5 synaptotagmin V -2.45583
DRC7 dynein regulatory complex subunit 7 -2.45583
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -2.45583
CER1 cerberus 1, DAN family BMP antagonist -2.45583
WNT4 wingless-type MMTV integration site family, member 4 -2.45583
JPH2 junctophilin 2 -2.45583
ANKRD54 ankyrin repeat domain 54 -2.45583
GNG3 guanine nucleotide binding protein (G protein), gamma 3 -2.45583
LYPD1 LY6/PLAUR domain containing 1 -2.45583
PROCR protein C receptor, endothelial -2.43148
H3C4 H3 clustered histone 4 -2.40909
MYH11 myosin, heavy chain 11, smooth muscle -2.40909
RNF166 ring finger protein 166 -2.39639
FANCI Fanconi anemia, complementation group I -2.39598
SNX19 sorting nexin 19 -2.35958
KIF26A kinesin family member 26A -2.33259
DENND10 DENN domain containing 10 -2.32779
NXPH2 neurexophilin 2 -2.32005
CORO1A coronin, actin binding protein, 1A -2.28259
COMMD4 COMM domain containing 4 -2.26725
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -2.23605
NBDY negative regulator of P-body association -2.23605
NINJ2 ninjurin 2 -2.23524
LAMA4 laminin, alpha 4 -2.2264
ZNF557 zinc finger protein 557 -2.21884
LAMA2 laminin, alpha 2 -2.21884
KCTD4 potassium channel tetramerization domain containing 4 -2.1979
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 -2.19562
ADI1 acireductone dioxygenase 1 -2.19246
WASHC3 WASH complex subunit 3 -2.18169
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.17982
HSPH1 heat shock 105kDa/110kDa protein 1 -2.17982
ZNF461 zinc finger protein 461 -2.17473
CKAP5 cytoskeleton associated protein 5 -2.16477
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -2.15258
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -2.152
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 -2.14391
MALL mal, T-cell differentiation protein-like -2.13991
CRTAC1 cartilage acidic protein 1 -2.13814
RAD9B RAD9 homolog B (S. pombe) -2.13814
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -2.13288
CIB2 calcium and integrin binding family member 2 -2.11638
TMEM53 transmembrane protein 53 -2.11638
PHLDB1 pleckstrin homology-like domain, family B, member 1 -2.09805
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 -2.08642
OCLN occludin -2.08642
MIPEP mitochondrial intermediate peptidase -2.08579
SKP1 S-phase kinase-associated protein 1 -2.07697
PRMT8 protein arginine methyltransferase 8 -2.07164
FLT4 fms-related tyrosine kinase 4 -2.07144
PTBP2 polypyrimidine tract binding protein 2 -2.07144
LYPD3 LY6/PLAUR domain containing 3 -2.07144
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -2.07102
CDK4 cyclin-dependent kinase 4 -2.05213
BRSK2 BR serine/threonine kinase 2 -2.0499
SNX8 sorting nexin 8 -2.03737
RETREG2 reticulophagy regulator family member 2 -2.03714
AP4M1 adaptor-related protein complex 4, mu 1 subunit -2.01586
TGFBR3 transforming growth factor, beta receptor III -2.01173
MDK midkine (neurite growth-promoting factor 2) -2.01173
SRSF11 serine/arginine-rich splicing factor 11 -2.01078
PAN3 PAN3 poly(A) specific ribonuclease subunit -2.01078
TMCC1 transmembrane and coiled-coil domain family 1 -2.01078
CHD8 chromodomain helicase DNA binding protein 8 -2.0031
SYT10 synaptotagmin X -2.00058