NADPH oxidase complex Gene Set

Dataset	GO Cellular Component Annotations 2023
Category	structural or functional annotations
Type	biological process
Description	A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2. (Gene Ontology, GO_0043020)
External Link	http://amigo.geneontology.org/amigo/term/GO:0043020
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Genes

18 proteins localized to the NADPH oxidase complex cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol	Name
CYBA	cytochrome b-245, alpha polypeptide
CYBB	cytochrome b-245, beta polypeptide
DUOX1	dual oxidase 1
DUOX2	dual oxidase 2
NCF1	neutrophil cytosolic factor 1
NCF1B	neutrophil cytosolic factor 1B pseudogene
NCF1C	neutrophil cytosolic factor 1C pseudogene
NCF2	neutrophil cytosolic factor 2
NCF4	neutrophil cytosolic factor 4, 40kDa
NOX1	NADPH oxidase 1
NOX3	NADPH oxidase 3
NOX4	NADPH oxidase 4
NOX5	NADPH oxidase, EF-hand calcium binding domain 5
NOXA1	NADPH oxidase activator 1
NOXO1	NADPH oxidase organizer 1
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)