NADPH oxidase complex Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2. (Gene Ontology, GO_0043020)
External Link http://amigo.geneontology.org/amigo/term/GO:0043020
Similar Terms
Downloads & Tools

Genes

16 proteins localized to the NADPH oxidase complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
NCF1 neutrophil cytosolic factor 1
NCF2 neutrophil cytosolic factor 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NCOA3 nuclear receptor coactivator 3
NOX1 NADPH oxidase 1
NOX3 NADPH oxidase 3
NOX4 NADPH oxidase 4
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NOXA1 NADPH oxidase activator 1
NOXO1 NADPH oxidase organizer 1
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)