NAT1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description N-acetyltransferase 1 (arylamine N-acetyltransferase)|This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 9)
External Link https://ncbi.nlm.nih.gov/gene/9
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Genes

499 genes differentially expressed following the NAT1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAGEA3 melanoma antigen family A3 0.0199576
HSPA1A heat shock 70kDa protein 1A 0.0181376
MAGEA12 melanoma antigen family A12 0.0159941
GNAS GNAS complex locus 0.0140655
S100P S100 calcium binding protein P 0.0124552
MAGEA1 melanoma antigen family A1 0.0120399
MAGEA4 melanoma antigen family A4 0.0115532
KRT18 keratin 18, type I 0.0105721
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.0101686
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00984906
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00939236
PLAAT3 phospholipase A and acyltransferase 3 0.00907273
MAL mal, T-cell differentiation protein 0.00901647
MCAM melanoma cell adhesion molecule 0.0089627
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00879007
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.00878655
GAB2 GRB2-associated binding protein 2 0.00866601
RPS4Y1 ribosomal protein S4, Y-linked 1 0.00853824
PRAME preferentially expressed antigen in melanoma 0.00831961
HSPH1 heat shock 105kDa/110kDa protein 1 0.0083103
APOLD1 apolipoprotein L domain containing 1 0.00809074
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.00803087
IL6ST interleukin 6 signal transducer 0.00795813
BAG3 BCL2-associated athanogene 3 0.00787449
RGS5 regulator of G-protein signaling 5 0.00782329
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0077859
ATF3 activating transcription factor 3 0.00754455
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00753963
ITGA6 integrin, alpha 6 0.0074713
EGFL6 EGF-like-domain, multiple 6 0.00745316
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00744839
ATOX1 antioxidant 1 copper chaperone 0.00742173
LEF1 lymphoid enhancer-binding factor 1 0.00740315
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.00722314
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 0.00721625
MSLN mesothelin 0.00721492
CHMP4A charged multivesicular body protein 4A 0.00721088
HIST1H2BK histone cluster 1, H2bk 0.00710999
VWF von Willebrand factor 0.00707272
CHPT1 choline phosphotransferase 1 0.00706867
CXCL9 chemokine (C-X-C motif) ligand 9 0.00706609
KRT13 keratin 13, type I 0.00706353
GRB14 growth factor receptor-bound protein 14 0.00698399
CXCL13 chemokine (C-X-C motif) ligand 13 0.00696794
HHEX hematopoietically expressed homeobox 0.00694894
BCAP31 B-cell receptor-associated protein 31 0.00692536
NKX3-1 NK3 homeobox 1 0.00676108
MSMB microseminoprotein, beta- 0.0067481
AQP3 aquaporin 3 (Gill blood group) 0.00672794
PRKCQ protein kinase C, theta 0.00658552
KLK11 kallikrein-related peptidase 11 0.00657988
CAV2 caveolin 2 0.00655228
RXYLT1 ribitol xylosyltransferase 1 0.00655072
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00651807
RETREG1 reticulophagy regulator 1 0.00651602
HMGA1 high mobility group AT-hook 1 0.00651143
PNN pinin, desmosome associated protein 0.00650188
BMP2 bone morphogenetic protein 2 0.00649982
CXCL10 chemokine (C-X-C motif) ligand 10 0.00649838
PDE8B phosphodiesterase 8B 0.00649671
MTUS1 microtubule associated tumor suppressor 1 0.00648727
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.00648578
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.00646586
ADGRG2 adhesion G protein-coupled receptor G2 0.00644306
ZYX zyxin 0.00641534
WFDC2 WAP four-disulfide core domain 2 0.00640419
ANO1 anoctamin 1, calcium activated chloride channel 0.0063887
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.00635779
TBL1X transducin (beta)-like 1X-linked 0.0063525
ARG2 arginase 2 0.0063515
PPARG peroxisome proliferator-activated receptor gamma 0.00635006
RBPMS RNA binding protein with multiple splicing 0.00634259
EGLN1 egl-9 family hypoxia-inducible factor 1 0.00631821
CCNA2 cyclin A2 0.00628239
COL15A1 collagen, type XV, alpha 1 0.00625825
HSPB8 heat shock 22kDa protein 8 0.00624705
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00621385
PSPC1 paraspeckle component 1 0.00620154
PITX1 paired-like homeodomain 1 0.00618903
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.00616186
CHD7 chromodomain helicase DNA binding protein 7 0.00614581
ZNF281 zinc finger protein 281 0.00613843
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.00613683
LGALS13 lectin, galactoside-binding, soluble, 13 0.00611047
CD93 CD93 molecule 0.00609025
ANXA3 annexin A3 0.00606709
RRAD Ras-related associated with diabetes 0.00602398
SHTN1 shootin 1 0.00599364
TACSTD2 tumor-associated calcium signal transducer 2 0.00598204
COL9A3 collagen, type IX, alpha 3 0.00597073
IL1RN interleukin 1 receptor antagonist 0.00593056
RBM47 RNA binding motif protein 47 0.00588772
NELL2 NEL-like 2 (chicken) 0.00586725
NID1 nidogen 1 0.0058657
TM4SF1 transmembrane 4 L six family member 1 0.00585994
TFPI2 tissue factor pathway inhibitor 2 0.00584629
HIST1H2BD histone cluster 1, H2bd 0.00584249
LMO2 LIM domain only 2 (rhombotin-like 1) 0.0058331
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00582922
ARMCX6 armadillo repeat containing, X-linked 6 0.00582762
GSTA1 glutathione S-transferase alpha 1 0.00581635
TESC tescalcin 0.00575515
FKBP4 FK506 binding protein 4, 59kDa 0.00574016
ITM2A integral membrane protein 2A 0.00571979
KRT17 keratin 17, type I 0.00568158
MECOM MDS1 and EVI1 complex locus 0.00566581
ABLIM1 actin binding LIM protein 1 0.00564195
ATAD2 ATPase family, AAA domain containing 2 0.00563115
LRP4 low density lipoprotein receptor-related protein 4 0.00560182
ATP5F1E ATP synthase F1 subunit epsilon 0.00559384
CRIP1 cysteine-rich protein 1 (intestinal) 0.00558454
CTSH cathepsin H 0.00558316
SPINK1 serine peptidase inhibitor, Kazal type 1 0.00558121
MTF2 metal response element binding transcription factor 2 0.00557194
S100A10 S100 calcium binding protein A10 0.00552521
RFX5 regulatory factor X, 5 (influences HLA class II expression) 0.00550507
TKTL1 transketolase-like 1 0.00547624
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.00545556
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.00544956
SSX1 synovial sarcoma, X breakpoint 1 0.00543595
SEPTIN8 septin 8 0.00543261
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.0054282
TPTE transmembrane phosphatase with tensin homology 0.00541419
TSC22D1 TSC22 domain family, member 1 0.00539854
TCTA T-cell leukemia translocation altered 0.00539514
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.0053878
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.00537913
SLCO3A1 solute carrier organic anion transporter family, member 3A1 0.00536282
RUNX3 runt-related transcription factor 3 0.00533591
ANGPT2 angiopoietin 2 0.00532539
CNPY3 canopy FGF signaling regulator 3 0.00532464
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.00530486
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00529233
MAGEA11 melanoma antigen family A11 0.00526356
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0052484
YAP1 Yes-associated protein 1 0.00524721
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.00524469
ARGLU1 arginine and glutamate rich 1 0.00522666
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00521463
HIST1H2BH histone cluster 1, H2bh 0.00519847
DOCK9 dedicator of cytokinesis 9 0.0051712
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.00515977
ASB9 ankyrin repeat and SOCS box containing 9 0.00515323
ZNF185 zinc finger protein 185 (LIM domain) 0.00514458
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.00514362
PIR pirin (iron-binding nuclear protein) 0.00513919
SSR4 signal sequence receptor, delta 0.00512724
HSPA4L heat shock 70kDa protein 4-like 0.00511607
SGK1 serum/glucocorticoid regulated kinase 1 0.0050995
HMOX1 heme oxygenase 1 0.00509233
EPPK1 epiplakin 1 0.00509039
FAM50A family with sequence similarity 50, member A 0.00509002
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00507955
PDE10A phosphodiesterase 10A 0.00507692
EFHD2 EF-hand domain family, member D2 0.00507411
EIF6 eukaryotic translation initiation factor 6 0.00507338
AMDHD2 amidohydrolase domain containing 2 0.00506729
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00506547
ELMO1 engulfment and cell motility 1 0.00506482
CSRP2 cysteine and glycine-rich protein 2 0.00504733
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.00504388
CREBZF CREB/ATF bZIP transcription factor 0.00504037
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.00503751
KRT14 keratin 14, type I 0.0050239
ITM2C integral membrane protein 2C 0.00502293
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.00502163
CYTL1 cytokine-like 1 0.00501451
MEF2C myocyte enhancer factor 2C 0.00499247
FGFR2 fibroblast growth factor receptor 2 0.00498043
TSPAN8 tetraspanin 8 0.00497829
FOXE1 forkhead box E1 0.00496763
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00495731
HIST1H2AE histone cluster 1, H2ae 0.00492471
SASH1 SAM and SH3 domain containing 1 0.00491971
STK24 serine/threonine kinase 24 0.00491937
MTA1 metastasis associated 1 0.00490456
FYN FYN proto-oncogene, Src family tyrosine kinase 0.00488839
FXYD5 FXYD domain containing ion transport regulator 5 0.00488564
NOP56 NOP56 ribonucleoprotein 0.00487571
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.00486501
FNBP1 formin binding protein 1 0.00484722
ZMYM2 zinc finger, MYM-type 2 0.00484491
PTBP3 polypyrimidine tract binding protein 3 0.00483749
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.00483631
MICB MHC class I polypeptide-related sequence B 0.00483547
STC1 stanniocalcin 1 0.00483365
STXBP6 syntaxin binding protein 6 (amisyn) 0.00482593
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.00481665
FAM169A family with sequence similarity 169, member A 0.00480035
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) 0.00479341
ZHX2 zinc fingers and homeoboxes 2 0.00478796
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.00477707
GCLM glutamate-cysteine ligase, modifier subunit 0.00476895
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.00475965
DENND5A DENN/MADD domain containing 5A 0.00474668
EGR1 early growth response 1 0.00474222
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.00474187
KLF6 Kruppel-like factor 6 0.00473455
SMC1A structural maintenance of chromosomes 1A 0.00473415
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 0.0047339
ARHGAP29 Rho GTPase activating protein 29 0.00471886
LIMCH1 LIM and calponin homology domains 1 0.00471678
TXNL4A thioredoxin-like 4A 0.00471182
CD99 CD99 molecule 0.00471065
ARF3 ADP-ribosylation factor 3 0.00469692
RBM25 RNA binding motif protein 25 0.00469661
AKAP17A A kinase (PRKA) anchor protein 17A 0.00469273
SLPI secretory leukocyte peptidase inhibitor 0.00468995
BID BH3 interacting domain death agonist 0.00467859
COX6C cytochrome c oxidase subunit VIc 0.00467698
WBP11 WW domain binding protein 11 0.00467542
PSCA prostate stem cell antigen 0.00467446
ELOC elongin C 0.00465371
USP11 ubiquitin specific peptidase 11 0.00465229
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.00465089
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.00464301
TBC1D31 TBC1 domain family, member 31 0.0046422
TFF1 trefoil factor 1 0.0046275
HMGN3 high mobility group nucleosomal binding domain 3 0.00462468
KLF4 Kruppel-like factor 4 (gut) 0.00458966
HSPB1 heat shock 27kDa protein 1 0.00457861
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 0.00457176
MAGEB2 melanoma antigen family B2 0.00456462
SELE selectin E 0.00455725
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.0045483
AKAP12 A kinase (PRKA) anchor protein 12 0.00454572
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.00453506
MYH9 myosin, heavy chain 9, non-muscle 0.00453449
RPS26 ribosomal protein S26 0.00452266
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00452174
KPNB1 karyopherin (importin) beta 1 0.00452059
ANKRD10 ankyrin repeat domain 10 0.0045202
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.00450903
CXADR coxsackie virus and adenovirus receptor 0.00450215
INSR insulin receptor 0.00450184
DSG1 desmoglein 1 0.00450123
ICAM2 intercellular adhesion molecule 2 0.00450117
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00449682
ADAM10 ADAM metallopeptidase domain 10 0.00448909
BRD4 bromodomain containing 4 0.00448598
CAPG capping protein (actin filament), gelsolin-like 0.00448406
CD200 CD200 molecule 0.0044758
MID1 midline 1 0.00447078
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00446699
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.00446274
EPHA2 EPH receptor A2 0.00446191
YAF2 YY1 associated factor 2 0.00445716
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00445303
IL6R interleukin 6 receptor 0.00445154

decreased expression

Symbol Name Standardized Value
TXNDC9 thioredoxin domain containing 9 -0.0134168
EREG epiregulin -0.0133302
SEPP1 selenoprotein P, plasma, 1 -0.0117373
CXCL12 chemokine (C-X-C motif) ligand 12 -0.0113235
LTBP1 latent transforming growth factor beta binding protein 1 -0.0109793
SFRP4 secreted frizzled-related protein 4 -0.0103554
MFAP5 microfibrillar associated protein 5 -0.00994444
THBS1 thrombospondin 1 -0.0095112
DCN decorin -0.00949348
KLF10 Kruppel-like factor 10 -0.00944758
GAS1 growth arrest-specific 1 -0.00912316
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00899108
CD59 CD59 molecule, complement regulatory protein -0.00874694
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00866889
S100A8 S100 calcium binding protein A8 -0.00855041
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C -0.00846655
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00845464
GJA1 gap junction protein, alpha 1, 43kDa -0.00844382
S100A9 S100 calcium binding protein A9 -0.00825943
SDC1 syndecan 1 -0.00818361
COMP cartilage oligomeric matrix protein -0.00814904
IFITM2 interferon induced transmembrane protein 2 -0.00805984
STMN2 stathmin 2 -0.00774882
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 -0.00772171
IFI6 interferon, alpha-inducible protein 6 -0.0076765
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00758777
LOXL1 lysyl oxidase-like 1 -0.00758694
C14ORF132 chromosome 14 open reading frame 132 -0.00757532
NUSAP1 nucleolar and spindle associated protein 1 -0.00737297
IFITM1 interferon induced transmembrane protein 1 -0.00733173
IL13RA2 interleukin 13 receptor, alpha 2 -0.00729357
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00727192
COLEC12 collectin sub-family member 12 -0.00726336
ENC1 ectodermal-neural cortex 1 (with BTB domain) -0.00710574
ECI2 enoyl-CoA delta isomerase 2 -0.00709178
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00694799
COL11A1 collagen, type XI, alpha 1 -0.00692611
XYLT1 xylosyltransferase I -0.00691886
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.00683239
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) -0.00682308
LOX lysyl oxidase -0.0068159
FBLN1 fibulin 1 -0.00679265
TAGLN transgelin -0.00676458
IGFBP5 insulin-like growth factor binding protein 5 -0.00674056
THBS2 thrombospondin 2 -0.00670077
IL1R1 interleukin 1 receptor, type I -0.00669993
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -0.00667277
COG7 component of oligomeric golgi complex 7 -0.00660747
MCOLN1 mucolipin 1 -0.00660373
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) -0.00658667
EAF2 ELL associated factor 2 -0.0065692
FAM3C family with sequence similarity 3, member C -0.00656705
MT1E metallothionein 1E -0.0065418
MEN1 multiple endocrine neoplasia I -0.0065377
BEX1 brain expressed, X-linked 1 -0.00651536
SIRT3 sirtuin 3 -0.00651152
AEBP1 AE binding protein 1 -0.00643456
C3ORF14 chromosome 3 open reading frame 14 -0.00642363
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00642256
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 -0.00641804
GSE1 Gse1 coiled-coil protein -0.00639829
THY1 Thy-1 cell surface antigen -0.00639762
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00638124
TUBB2A tubulin, beta 2A class IIa -0.00637747
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00635416
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 -0.00630956
GLS glutaminase -0.00629207
LRRC15 leucine rich repeat containing 15 -0.00628425
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -0.00625267
DPYD dihydropyrimidine dehydrogenase -0.00625033
CEMIP cell migration inducing protein, hyaluronan binding -0.00622873
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -0.00620717
GLO1 glyoxalase I -0.00619463
TPBG trophoblast glycoprotein -0.00618237
CTSK cathepsin K -0.00615133
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 -0.00614357
WISP2 WNT1 inducible signaling pathway protein 2 -0.00611078
FOXC1 forkhead box C1 -0.00597842
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -0.00597286
LRP1 low density lipoprotein receptor-related protein 1 -0.00597044
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00597008
CPA3 carboxypeptidase A3 (mast cell) -0.00596596
AREG amphiregulin -0.00594188
IFRD2 interferon-related developmental regulator 2 -0.00592924
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00592645
CCNB1 cyclin B1 -0.00591858
CRYM crystallin, mu -0.00589424
TIPRL TOR signaling pathway regulator -0.00588684
WDR61 WD repeat domain 61 -0.00587987
CYB5R1 cytochrome b5 reductase 1 -0.00586753
CEL carboxyl ester lipase -0.00586727
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00583545
NFASC neurofascin -0.0058333
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -0.00577804
FSTL1 follistatin-like 1 -0.00576075
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase -0.00572613
TXNIP thioredoxin interacting protein -0.00571889
STEAP3 STEAP family member 3, metalloreductase -0.00570341
TBC1D16 TBC1 domain family, member 16 -0.00569422
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 -0.00568975
GPNMB glycoprotein (transmembrane) nmb -0.00568362
PLAT plasminogen activator, tissue -0.00567804
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -0.00565587
CD248 CD248 molecule, endosialin -0.00565586
MOXD1 monooxygenase, DBH-like 1 -0.00563357
KIFAP3 kinesin-associated protein 3 -0.00562781
FST follistatin -0.00561395
PXDN peroxidasin -0.00560222
UBE2N ubiquitin-conjugating enzyme E2N -0.00558873
SPON1 spondin 1, extracellular matrix protein -0.00556891
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00552909
TTC19 tetratricopeptide repeat domain 19 -0.0055184
LXN latexin -0.00545428
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -0.00543594
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00539825
GPM6B glycoprotein M6B -0.00537751
CHGB chromogranin B -0.0053687
COL6A3 collagen, type VI, alpha 3 -0.005365
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A -0.00535756
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00534267
ARID4A AT rich interactive domain 4A (RBP1-like) -0.00531119
SRPX sushi-repeat containing protein, X-linked -0.00530985
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 -0.0052901
MMP1 matrix metallopeptidase 1 -0.00524547
CCDC85B coiled-coil domain containing 85B -0.00523944
PDGFD platelet derived growth factor D -0.00523892
KIAA0125 KIAA0125 -0.00523388
GYPC glycophorin C (Gerbich blood group) -0.00523322
TAGLN3 transgelin 3 -0.0052292
C1QTNF3 C1q and tumor necrosis factor related protein 3 -0.00522675
KRCC1 lysine-rich coiled-coil 1 -0.00521428
PTK7 protein tyrosine kinase 7 (inactive) -0.00519662
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -0.00519141
UGDH UDP-glucose 6-dehydrogenase -0.0051901
IGFBP6 insulin-like growth factor binding protein 6 -0.0051659
PPA2 pyrophosphatase (inorganic) 2 -0.00516467
ALCAM activated leukocyte cell adhesion molecule -0.00514251
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) -0.00512606
TMEM159 transmembrane protein 159 -0.00510108
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.00509936
ACTA2 actin, alpha 2, smooth muscle, aorta -0.0050933
PEX11B peroxisomal biogenesis factor 11 beta -0.00508338
PON3 paraoxonase 3 -0.00506553
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00506295
SUMO3 small ubiquitin-like modifier 3 -0.00505559
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) -0.00502265
ANK2 ankyrin 2, neuronal -0.00502133
ASPN asporin -0.00501832
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -0.00499638
GLUL glutamate-ammonia ligase -0.00498179
TTC38 tetratricopeptide repeat domain 38 -0.00498179
SYT1 synaptotagmin I -0.00497364
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 -0.00497204
TUBB3 tubulin, beta 3 class III -0.0049388
ELN elastin -0.00493493
MXRA8 matrix-remodelling associated 8 -0.00493049
C4BPA complement component 4 binding protein, alpha -0.00492876
BPHL biphenyl hydrolase-like (serine hydrolase) -0.0049036
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.00489576
CDC25B cell division cycle 25B -0.00488225
BCL2A1 BCL2-related protein A1 -0.00487055
LRRC17 leucine rich repeat containing 17 -0.00486965
MCM6 minichromosome maintenance complex component 6 -0.00485406
RUNX1 runt-related transcription factor 1 -0.00484449
SSPN sarcospan -0.00483714
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.00483519
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00483438
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta -0.0048231
FBXO3 F-box protein 3 -0.00482203
APOD apolipoprotein D -0.00482173
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -0.00481515
EFHD1 EF-hand domain family, member D1 -0.00481051
VSIG4 V-set and immunoglobulin domain containing 4 -0.00480564
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -0.00479556
CTSZ cathepsin Z -0.00478891
RGS4 regulator of G-protein signaling 4 -0.00477012
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -0.00476474
INHBA inhibin, beta A -0.00476169
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.0047515
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -0.00474825
PDHX pyruvate dehydrogenase complex, component X -0.00474617
UROD uroporphyrinogen decarboxylase -0.00474415
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -0.00473241
GCA grancalcin, EF-hand calcium binding protein -0.00472353
RTN3 reticulon 3 -0.0047216
PDGFRL platelet-derived growth factor receptor-like -0.00470161
RTN2 reticulon 2 -0.00468653
ADARB1 adenosine deaminase, RNA-specific, B1 -0.00468473
MFAP2 microfibrillar-associated protein 2 -0.00468255
SUGCT succinyl-CoA:glutarate-CoA transferase -0.00467539
RCAN1 regulator of calcineurin 1 -0.00467194
GRSF1 G-rich RNA sequence binding factor 1 -0.00465284
TRIB2 tribbles pseudokinase 2 -0.00465161
SST somatostatin -0.00464251
INSM1 insulinoma-associated 1 -0.0046398
ALOX15B arachidonate 15-lipoxygenase, type B -0.00463758
CADM1 cell adhesion molecule 1 -0.00463644
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.00463202
JCHAIN joining chain of multimeric IgA and IgM -0.00463108
MAP7 microtubule-associated protein 7 -0.0046297
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -0.00462369
CYBRD1 cytochrome b reductase 1 -0.00462114
HMGN4 high mobility group nucleosomal binding domain 4 -0.00460764
DCK deoxycytidine kinase -0.00459023
DENND1B DENN/MADD domain containing 1B -0.00459004
KIF1A kinesin family member 1A -0.0045814
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00457669
SLC26A2 solute carrier family 26 (anion exchanger), member 2 -0.00457595
HOXB5 homeobox B5 -0.00456821
GFPT2 glutamine-fructose-6-phosphate transaminase 2 -0.0045638
CCNB2 cyclin B2 -0.00456041
TSPYL1 TSPY-like 1 -0.00454682
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -0.00453289
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -0.00452794
SALL2 spalt-like transcription factor 2 -0.00452378
LY96 lymphocyte antigen 96 -0.004515
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.00450505
LEPR leptin receptor -0.00448907
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00448017
BMI1 BMI1 proto-oncogene, polycomb ring finger -0.0044725
IDO1 indoleamine 2,3-dioxygenase 1 -0.0044543
IRX5 iroquois homeobox 5 -0.00444449
COMMD8 COMM domain containing 8 -0.00444157
CDO1 cysteine dioxygenase type 1 -0.00443967
SOCS5 suppressor of cytokine signaling 5 -0.00443198
GFAP glial fibrillary acidic protein -0.00441692
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like -0.00440634
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00440511
RPL10 ribosomal protein L10 -0.00440212
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -0.0043851
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00438231
ENO2 enolase 2 (gamma, neuronal) -0.00438095
GPM6A glycoprotein M6A -0.00437736
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -0.00437396
KIAA1109 KIAA1109 -0.00437243
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) -0.00437139
HBD hemoglobin, delta -0.00436989
NOTCH2 notch 2 -0.00436892
PLAU plasminogen activator, urokinase -0.00435801
SCRG1 stimulator of chondrogenesis 1 -0.00435762
C12ORF29 chromosome 12 open reading frame 29 -0.00435661
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -0.00435481
EIF5A eukaryotic translation initiation factor 5A -0.00435249
NID2 nidogen 2 (osteonidogen) -0.00434936
SNCAIP synuclein, alpha interacting protein -0.00431822
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -0.00431725
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha -0.00431538
CIT citron rho-interacting serine/threonine kinase -0.00431268
SMYD3 SET and MYND domain containing 3 -0.00430662
ITGB4 integrin, beta 4 -0.00430556