NCI-H146 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Small Cell Lung Carcinoma Metastasis (Cell Model Passports, SIDM00698)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00698
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Genes

195 proteins associated with the cell line NCI-H146 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ABRACL ABRA C-terminal like
ACTL6A actin-like 6A
AIP aryl hydrocarbon receptor interacting protein
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ARFGEF3 ARFGEF family member 3
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
C12ORF57 chromosome 12 open reading frame 57
CAMK1D calcium/calmodulin-dependent protein kinase ID
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CC2D1A coiled-coil and C2 domain containing 1A
CCP110 centriolar coiled coil protein 110kDa
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CD47 CD47 molecule
CDK4 cyclin-dependent kinase 4
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CHMP1B charged multivesicular body protein 1B
CKB creatine kinase, brain
CNBP CCHC-type zinc finger, nucleic acid binding protein
CORO7 coronin 7
CTSH cathepsin H
DCLK1 doublecortin-like kinase 1
DHPS deoxyhypusine synthase
DPY30 dpy-30 homolog (C. elegans)
DTD1 D-tyrosyl-tRNA deacylase 1
ENOPH1 enolase-phosphatase 1
ENY2 enhancer of yellow 2 homolog (Drosophila)
ERICH5 glutamate-rich 5
FXR1 fragile X mental retardation, autosomal homolog 1
FXR2 fragile X mental retardation, autosomal homolog 2
GCDH glutaryl-CoA dehydrogenase
GDI1 GDP dissociation inhibitor 1
GSK3B glycogen synthase kinase 3 beta
HAGH hydroxyacylglutathione hydrolase
HDAC4 histone deacetylase 4
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HOOK1 hook microtubule-tethering protein 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IGFBPL1 insulin-like growth factor binding protein-like 1
INPPL1 inositol polyphosphate phosphatase-like 1
IRGQ immunity-related GTPase family, Q
KCTD12 potassium channel tetramerization domain containing 12
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIF3B kinesin family member 3B
KLC1 kinesin light chain 1
KLC4 kinesin light chain 4
LONP2 lon peptidase 2, peroxisomal
MAGEC2 melanoma antigen family C2
MAP1B microtubule-associated protein 1B
MOCS2 molybdenum cofactor synthesis 2
MTA1 metastasis associated 1
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NEBL nebulette
NEGR1 neuronal growth regulator 1
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRTFDC1 phosphoribosyl transferase domain containing 1
PTER phosphotriesterase related
REPS1 RALBP1 associated Eps domain containing 1
RPRD1A regulation of nuclear pre-mRNA domain containing 1A
RUFY3 RUN and FYVE domain containing 3
SAMD4B sterile alpha motif domain containing 4B
SENP1 SUMO1/sentrin specific peptidase 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SMAD4 SMAD family member 4
TAGLN3 transgelin 3
TBCB tubulin folding cofactor B
TBCC tubulin folding cofactor C
TCEAL4 transcription elongation factor A (SII)-like 4
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TPD52 tumor protein D52
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBB2B tubulin, beta 2B class IIb
UBA6 ubiquitin-like modifier activating enzyme 6
UBE2H ubiquitin-conjugating enzyme E2H
UBE3C ubiquitin protein ligase E3C
UBQLN2 ubiquilin 2
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UMPS uridine monophosphate synthetase
USP11 ubiquitin specific peptidase 11
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
XPO5 exportin 5
XPO6 exportin 6
ZADH2 zinc binding alcohol dehydrogenase domain containing 2
ZNF24 zinc finger protein 24
ZNF428 zinc finger protein 428
ZNF638 zinc finger protein 638

Symbol Name
AASTH16 Allergic/atopic asthma related QTL 16
ACSS1 acyl-CoA synthetase short-chain family member 1
ADGB androglobin
ADGRE5 adhesion G protein-coupled receptor E5
ANKRD30B ankyrin repeat domain 30B
ARRDC1 arrestin domain containing 1
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
C1ORF109 chromosome 1 open reading frame 109
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CALCA calcitonin-related polypeptide alpha
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CD44 CD44 molecule (Indian blood group)
CENPQ centromere protein Q
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COMT catechol-O-methyltransferase
CORO2A coronin, actin binding protein, 2A
CTSA cathepsin A
CTTNBP2NL CTTNBP2 N-terminal like
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DHODH dihydroorotate dehydrogenase (quinone)
DUSP3 dual specificity phosphatase 3
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EHBP1L1 EH domain binding protein 1-like 1
ERGIC2 ERGIC and golgi 2
ETFA electron-transfer-flavoprotein, alpha polypeptide
ETFB electron-transfer-flavoprotein, beta polypeptide
ETFDH electron-transferring-flavoprotein dehydrogenase
FAM8A1 family with sequence similarity 8, member A1
FTL ferritin, light polypeptide
GAB2 GRB2-associated binding protein 2
GALC galactosylceramidase
GOLGA4 golgin A4
GPC6 glypican 6
GRP gastrin-releasing peptide
HLA-B major histocompatibility complex, class I, B
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HSDL2 hydroxysteroid dehydrogenase like 2
IGSF3 immunoglobulin superfamily, member 3
IRS4 insulin receptor substrate 4
KIAA0586 KIAA0586
LDB1 LIM domain binding 1
LOC105371242 peptidyl-prolyl cis-trans isomerase A-like 4G
LPP LIM domain containing preferred translocation partner in lipoma
LRSAM1 leucine rich repeat and sterile alpha motif containing 1
MAPK15 mitogen-activated protein kinase 15
MBNL1 muscleblind-like splicing regulator 1
MED27 mediator complex subunit 27
METAP1 methionyl aminopeptidase 1
METTL2B methyltransferase like 2B
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLEC malectin
MTMR11 myotubularin related protein 11
MYOZ2 myozenin 2
NCKAP1L NCK-associated protein 1-like
NDC1 NDC1 transmembrane nucleoporin
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
NF2 neurofibromin 2 (merlin)
NME3 NME/NM23 nucleoside diphosphate kinase 3
NME6 NME/NM23 nucleoside diphosphate kinase 6
NOP58 NOP58 ribonucleoprotein
ORC1 origin recognition complex, subunit 1
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX14 peroxisomal biogenesis factor 14
PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLIN3 perilipin 3
PNPLA8 patatin-like phospholipase domain containing 8
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R16A protein phosphatase 1, regulatory subunit 16A
RCC1 regulator of chromosome condensation 1
RHOC ras homolog family member C
RPL37A ribosomal protein L37a
RPS27L ribosomal protein S27-like
RSPRY1 ring finger and SPRY domain containing 1
S100A11 S100 calcium binding protein A11
S100A16 S100 calcium binding protein A16
SAR1B secretion associated, Ras related GTPase 1B
SHCBP1 SHC SH2-domain binding protein 1
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAP23 synaptosomal-associated protein, 23kDa
TCEAL5 transcription elongation factor A (SII)-like 5
THRAP3 thyroid hormone receptor associated protein 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM201 transmembrane protein 201
TRIM56 tripartite motif containing 56
UBL7 ubiquitin-like 7
USP36 ubiquitin specific peptidase 36
WDFY1 WD repeat and FYVE domain containing 1
WDPCP WD repeat containing planar cell polarity effector
WDR55 WD repeat domain 55
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFAND1 zinc finger, AN1-type domain 1
ZMPSTE24 zinc metallopeptidase STE24
ZNF106 zinc finger protein 106