NCI-H1623 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Non-Small Cell Lung Carcinoma Metastasis (Cell Model Passports, SIDM00747)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00747
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Genes

196 proteins associated with the cell line NCI-H1623 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
ACAA1 acetyl-CoA acyltransferase 1
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAR adenosine deaminase, RNA-specific
AGPS alkylglycerone phosphate synthase
ARL8B ADP-ribosylation factor-like 8B
ASPH aspartate beta-hydroxylase
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
CAAP1 caspase activity and apoptosis inhibitor 1
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHTOP chromatin target of PRMT1
CIP2A cellular inhibitor of PP2A
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTSL cathepsin L
DHFR dihydrofolate reductase
DHRS4 dehydrogenase/reductase (SDR family) member 4
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
ECH1 enoyl CoA hydratase 1, peroxisomal
EDN3 endothelin 3
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ETFB electron-transfer-flavoprotein, beta polypeptide
FDX1 ferredoxin 1
FECH ferrochelatase
FHOD1 formin homology 2 domain containing 1
GCLM glutamate-cysteine ligase, modifier subunit
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GNL1 guanine nucleotide binding protein-like 1
GRIPAP1 GRIP1 associated protein 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAUS8 HAUS augmin-like complex, subunit 8
HAX1 HCLS1 associated protein X-1
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
IKBIP IKBKB interacting protein
IMMT inner membrane protein, mitochondrial
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
L1RE1 LINE1 retrotransposable element 1
LACTB2 lactamase, beta 2
LEMD3 LEM domain containing 3
LIG3 ligase III, DNA, ATP-dependent
LIMCH1 LIM and calponin homology domains 1
LPGAT1 lysophosphatidylglycerol acyltransferase 1
MED4 mediator complex subunit 4
MFF mitochondrial fission factor
MFGE8 milk fat globule-EGF factor 8 protein
MGST1 microsomal glutathione S-transferase 1
MT-ATP8 ATP synthase F0 subunit 8
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTIF3 mitochondrial translational initiation factor 3
MYH14 myosin, heavy chain 14, non-muscle
MYO19 myosin XIX
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
NOTCH3 notch 3
NPR2 natriuretic peptide receptor 2
NSMCE1 non-SMC element 1 homolog (S. cerevisiae)
PNKP polynucleotide kinase 3'-phosphatase
POLR1E polymerase (RNA) I polypeptide E, 53kDa
PPA2 pyrophosphatase (inorganic) 2
PUM1 pumilio RNA-binding family member 1
RAB10 RAB10, member RAS oncogene family
RAB13 RAB13, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RMDN1 regulator of microtubule dynamics 1
RMDN3 regulator of microtubule dynamics 3
RNF213 ring finger protein 213
RPRD2 regulation of nuclear pre-mRNA domain containing 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SFPQ splicing factor proline/glutamine-rich
SFXN1 sideroflexin 1
SIPA1 signal-induced proliferation-associated 1
SLTM SAFB-like, transcription modulator
SON SON DNA binding protein
SRXN1 sulfiredoxin 1
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
SUN5 Sad1 and UNC84 domain containing 5
TADA1 transcriptional adaptor 1
TDRKH tudor and KH domain containing
TM9SF2 transmembrane 9 superfamily member 2
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast)
TREX1 three prime repair exonuclease 1
TSC2 tuberous sclerosis 2
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
TTC22 tetratricopeptide repeat domain 22
UQCRB ubiquinol-cytochrome c reductase binding protein
VSIG10L V-set and immunoglobulin domain containing 10 like
WDR46 WD repeat domain 46
YBEY ybeY metallopeptidase (putative)
YEATS4 YEATS domain containing 4
ZMYND11 zinc finger, MYND-type containing 11
ZNF638 zinc finger protein 638
ZNHIT2 zinc finger, HIT-type containing 2

Symbol Name
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
AMPD2 adenosine monophosphate deaminase 2
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARFGAP2 ADP-ribosylation factor GTPase activating protein 2
ARL2 ADP-ribosylation factor-like 2
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
BSDC1 BSD domain containing 1
C9ORF40 chromosome 9 open reading frame 40
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCM2 cerebral cavernous malformation 2
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDK1 cyclin-dependent kinase 1
CHAF1B chromatin assembly factor 1, subunit B (p60)
CNN3 calponin 3, acidic
COG5 component of oligomeric golgi complex 5
COG6 component of oligomeric golgi complex 6
COPB1 coatomer protein complex, subunit beta 1
COPE coatomer protein complex, subunit epsilon
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF3 colony stimulating factor 3 (granulocyte)
DBNL drebrin-like
DDB1 damage-specific DNA binding protein 1, 127kDa
DENR density-regulated protein
DYNLRB1 dynein, light chain, roadblock-type 1
EDC4 enhancer of mRNA decapping 4
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF4A1 eukaryotic translation initiation factor 4A1
EIF5B eukaryotic translation initiation factor 5B
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ERVK-5 endogenous retrovirus group K, member 5
ETF1 eukaryotic translation termination factor 1
EXOSC3 exosome component 3
GAPVD1 GTPase activating protein and VPS9 domains 1
GPATCH11 G patch domain containing 11
GVINP1 GTPase, very large interferon inducible pseudogene 1
GYG1 glycogenin 1
GYS1 glycogen synthase 1 (muscle)
IPO5 importin 5
IRF2BP2 interferon regulatory factor 2 binding protein 2
LARP1 La ribonucleoprotein domain family, member 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MEAF6 MYST/Esa1-associated factor 6
MOCS1 molybdenum cofactor synthesis 1
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NCAPH non-SMC condensin I complex, subunit H
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
NLGN1 neuroligin 1
NMNAT3 nicotinamide nucleotide adenylyltransferase 3
NRM nurim (nuclear envelope membrane protein)
OTUD4 OTU deubiquitinase 4
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAK1IP1 PAK1 interacting protein 1
PBK PDZ binding kinase
PFDN4 prefoldin subunit 4
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RANGAP1 Ran GTPase activating protein 1
RFC5 replication factor C (activator 1) 5, 36.5kDa
RNMT RNA (guanine-7-) methyltransferase
RPL26 ribosomal protein L26
RWDD3 RWD domain containing 3
SEC23IP SEC23 interacting protein
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SNX4 sorting nexin 4
SRFBP1 serum response factor binding protein 1
TCP1 t-complex 1
TEX2 testis expressed 2
THEM4 thioesterase superfamily member 4
TPP2 tripeptidyl peptidase II
TRAPPC8 trafficking protein particle complex 8
TSN translin
TSNAX translin-associated factor X
TXNDC17 thioredoxin domain containing 17
UBA6 ubiquitin-like modifier activating enzyme 6
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBE4A ubiquitination factor E4A
USO1 USO1 vesicle transport factor
VIP vasoactive intestinal peptide
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
VTA1 vesicle (multivesicular body) trafficking 1
WDR82 WD repeat domain 82
ZMYND8 zinc finger, MYND-type containing 8
ZNF598 zinc finger protein 598