NCI-H1703 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
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Genes

279 genes with high or low expression in NCI-H1703 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
OCRL oculocerebrorenal syndrome of Lowe 3.3603
MAPK12 mitogen-activated protein kinase 12 3.09566
MAPK11 mitogen-activated protein kinase 11 3.09122
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.88253
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 2.59974
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 2.45423
RECQL RecQ helicase-like 2.40894
CNTNAP1 contactin associated protein 1 2.40094
KIF1C kinesin family member 1C 2.35148
MLF2 myeloid leukemia factor 2 2.1851
HMOX1 heme oxygenase 1 2.1845
PROSC proline synthetase co-transcribed homolog (bacterial) 2.13436
DDHD2 DDHD domain containing 2 2.09489
NUP155 nucleoporin 155kDa 2.07435
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 2.06257
KIF4A kinesin family member 4A 2.03692
MPPE1 metallophosphoesterase 1 2.03498
HAUS7 HAUS augmin-like complex, subunit 7 2.02759
NTAN1 N-terminal asparagine amidase 2.02601
CEP55 centrosomal protein 55kDa 2.02325
FOXM1 forkhead box M1 1.9925
APEH acylaminoacyl-peptide hydrolase 1.97448
NRG2 neuregulin 2 1.95603
ICE1 interactor of little elongation complex ELL subunit 1 1.95475
PDGFB platelet-derived growth factor beta polypeptide 1.93503
HDAC3 histone deacetylase 3 1.91293
PDE4A phosphodiesterase 4A, cAMP-specific 1.90325
NSDHL NAD(P) dependent steroid dehydrogenase-like 1.90143
PADI2 peptidyl arginine deiminase, type II 1.89964
NR2F6 nuclear receptor subfamily 2, group F, member 6 1.87035
RPA1 replication protein A1, 70kDa 1.86506
PTMS parathymosin 1.84618
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.8364
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 1.83589
TBXA2R thromboxane A2 receptor 1.8358
FOXJ2 forkhead box J2 1.82577
GAS2L1 growth arrest-specific 2 like 1 1.82468
BAG4 BCL2-associated athanogene 4 1.82119
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 1.79881
STYK1 serine/threonine/tyrosine kinase 1 1.7955
CERS2 ceramide synthase 2 1.79181
CUEDC2 CUE domain containing 2 1.79112
LSM1 LSM1, U6 small nuclear RNA associated 1.77911
RASL10A RAS-like, family 10, member A 1.76404
PEMT phosphatidylethanolamine N-methyltransferase 1.74586
MCM5 minichromosome maintenance complex component 5 1.73763
NR2F1 nuclear receptor subfamily 2, group F, member 1 1.73698
PDGFC platelet derived growth factor C 1.7364
LAMC3 laminin, gamma 3 1.72935
TEAD4 TEA domain family member 4 1.72734
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 1.72561
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 1.72265
ATN1 atrophin 1 1.72
MAGEA1 melanoma antigen family A1 1.71167
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 1.70292
BRD9 bromodomain containing 9 1.6987
SLITRK5 SLIT and NTRK-like family, member 5 1.69427
ZAK sterile alpha motif and leucine zipper containing kinase AZK 1.69414
C1RL complement component 1, r subcomponent-like 1.69138
TNNT1 troponin T type 1 (skeletal, slow) 1.68775
TRIP13 thyroid hormone receptor interactor 13 1.65635
HMGN4 high mobility group nucleosomal binding domain 4 1.65589
TULP3 tubby like protein 3 1.62319
MARCH2 membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase 1.62134
PIAS3 protein inhibitor of activated STAT, 3 1.61742
MYO1C myosin IC 1.61621
ZNF467 zinc finger protein 467 1.61561
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 1.61459
WNK1 WNK lysine deficient protein kinase 1 1.61448
FAM155B family with sequence similarity 155, member B 1.60309
MTRF1L mitochondrial translational release factor 1-like 1.59494
FAM63A family with sequence similarity 63, member A 1.5942
ADIPOR2 adiponectin receptor 2 1.59061
SDHAP1 succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1 1.58561
MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase 1.58029
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.57941
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 1.5736
TMEM14B transmembrane protein 14B 1.57241
RAB5C RAB5C, member RAS oncogene family 1.57028
NAGA N-acetylgalactosaminidase, alpha- 1.56525
HEXIM1 hexamethylene bis-acetamide inducible 1 1.56123
CLSTN3 calsyntenin 3 1.54546
INA internexin neuronal intermediate filament protein, alpha 1.53814
CPNE7 copine VII 1.53725
MTMR11 myotubularin related protein 11 1.53492
WBP11 WW domain binding protein 11 1.53408
PLA2G2E phospholipase A2, group IIE 1.52985
TRIO trio Rho guanine nucleotide exchange factor 1.52768
CIC capicua transcriptional repressor 1.52523
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 1.52436
HPS1 Hermansky-Pudlak syndrome 1 1.52286
NME4 NME/NM23 nucleoside diphosphate kinase 4 1.52005
MAP3K12 mitogen-activated protein kinase kinase kinase 12 1.5189
GLI1 GLI family zinc finger 1 1.51562
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 1.50749
EMG1 EMG1 N1-specific pseudouridine methyltransferase 1.50581
PLD2 phospholipase D2 1.4989
NEFH neurofilament, heavy polypeptide 1.4949
NRBP1 nuclear receptor binding protein 1 1.48794
ADGRL2 adhesion G protein-coupled receptor L2 1.48563
VARS valyl-tRNA synthetase 1.48295
STX10 syntaxin 10 1.48254
CBX6 chromobox homolog 6 1.48012
CEP70 centrosomal protein 70kDa 1.47479
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 1.47089
NCAPD2 non-SMC condensin I complex, subunit D2 1.46821
SF3B4 splicing factor 3b, subunit 4, 49kDa 1.46726
TARBP1 TAR (HIV-1) RNA binding protein 1 1.46638
IQCE IQ motif containing E 1.46442
SGK1 serum/glucocorticoid regulated kinase 1 1.46303
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.45759
MICA MHC class I polypeptide-related sequence A 1.45751
SRA1 steroid receptor RNA activator 1 1.45718
KCTD17 potassium channel tetramerization domain containing 17 1.45663
SIX3 SIX homeobox 3 1.45239
OCEL1 occludin/ELL domain containing 1 1.45048
DIAPH2 diaphanous-related formin 2 1.45042
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 1.44795
IFT27 intraflagellar transport 27 1.44612
BAG3 BCL2-associated athanogene 3 1.4399
CIB1 calcium and integrin binding 1 (calmyrin) 1.43962
SNF8 SNF8, ESCRT-II complex subunit 1.43902
CDCA3 cell division cycle associated 3 1.4354
TOR1AIP2 torsin A interacting protein 2 1.43153
DLC1 DLC1 Rho GTPase activating protein 1.42698
ZFR zinc finger RNA binding protein 1.42333
LDB1 LIM domain binding 1 1.41936
NUP43 nucleoporin 43kDa 1.41743
USP46 ubiquitin specific peptidase 46 1.41685
WDR70 WD repeat domain 70 1.41669

low expression

Symbol Name Standardized Value
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 -3.53725
CTSZ cathepsin Z -2.90963
CLDN3 claudin 3 -2.89882
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) -2.76738
TSG101 tumor susceptibility 101 -2.67739
RANGRF RAN guanine nucleotide release factor -2.62895
NCR2 natural cytotoxicity triggering receptor 2 -2.61321
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 -2.5233
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 -2.50251
OXNAD1 oxidoreductase NAD-binding domain containing 1 -2.49822
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -2.45776
LIG4 ligase IV, DNA, ATP-dependent -2.43223
GCHFR GTP cyclohydrolase I feedback regulator -2.36099
PTX3 pentraxin 3, long -2.35395
KIF13B kinesin family member 13B -2.31632
IPO4 importin 4 -2.28926
BTG1 B-cell translocation gene 1, anti-proliferative -2.28883
PDHX pyruvate dehydrogenase complex, component X -2.27418
CADM3 cell adhesion molecule 3 -2.26031
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -2.25044
CALHM2 calcium homeostasis modulator 2 -2.20555
CBR3 carbonyl reductase 3 -2.19569
SARAF store-operated calcium entry-associated regulatory factor -2.17989
ZNF586 zinc finger protein 586 -2.17934
RGS3 regulator of G-protein signaling 3 -2.17776
PRDX2 peroxiredoxin 2 -2.17739
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) -2.16714
NPR2 natriuretic peptide receptor 2 -2.15525
EFNB2 ephrin-B2 -2.14141
SAMD9 sterile alpha motif domain containing 9 -2.13469
MDK midkine (neurite growth-promoting factor 2) -2.12085
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -2.1155
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 -2.11265
BAMBI BMP and activin membrane-bound inhibitor -2.1047
KIAA0020 KIAA0020 -2.04535
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -2.03594
MGST2 microsomal glutathione S-transferase 2 -2.0208
HAO2 hydroxyacid oxidase 2 (long chain) -2.0159
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.01477
PLA2G5 phospholipase A2, group V -2.00381
PAH phenylalanine hydroxylase -2.0016
ADAM2 ADAM metallopeptidase domain 2 -2.00099
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -1.99072
ANKRD7 ankyrin repeat domain 7 -1.94318
APIP APAF1 interacting protein -1.93895
RLN2 relaxin 2 -1.93003
IFI16 interferon, gamma-inducible protein 16 -1.91435
TMEM80 transmembrane protein 80 -1.91119
GTF2B general transcription factor IIB -1.89069
CIITA class II, major histocompatibility complex, transactivator -1.89029
MYH15 myosin, heavy chain 15 -1.87009
CSF1R colony stimulating factor 1 receptor -1.86609
ZNF195 zinc finger protein 195 -1.84664
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) -1.8276
MAN1C1 mannosidase, alpha, class 1C, member 1 -1.82188
AQP3 aquaporin 3 (Gill blood group) -1.81221
TSC22D3 TSC22 domain family, member 3 -1.81107
TNS1 tensin 1 -1.7815
CADPS2 Ca++-dependent secretion activator 2 -1.77139
QDPR quinoid dihydropteridine reductase -1.76146
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide -1.75034
GLRX glutaredoxin (thioltransferase) -1.7469
GAST gastrin -1.74088
NTN1 netrin 1 -1.73987
FKRP fukutin related protein -1.71901
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 -1.71655
ASS1 argininosuccinate synthase 1 -1.71522
STAP2 signal transducing adaptor family member 2 -1.71082
MYBPC3 myosin binding protein C, cardiac -1.71075
PLA2G10 phospholipase A2, group X -1.70556
TSPAN31 tetraspanin 31 -1.70402
PDGFD platelet derived growth factor D -1.69492
S100A13 S100 calcium binding protein A13 -1.6938
RNF114 ring finger protein 114 -1.68865
JAG1 jagged 1 -1.68807
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa -1.68773
HNF4A hepatocyte nuclear factor 4, alpha -1.681
NFE2 nuclear factor, erythroid 2 -1.66797
SRPX2 sushi-repeat containing protein, X-linked 2 -1.66673
CDC37L1 cell division cycle 37-like 1 -1.65665
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 -1.65234
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 -1.65109
NR4A1 nuclear receptor subfamily 4, group A, member 1 -1.64536
ABHD4 abhydrolase domain containing 4 -1.6388
FSTL4 follistatin-like 4 -1.63378
DENND2A DENN/MADD domain containing 2A -1.62864
ELP3 elongator acetyltransferase complex subunit 3 -1.62599
COMMD3 COMM domain containing 3 -1.62413
PTGDR prostaglandin D2 receptor (DP) -1.61355
ACSM3 acyl-CoA synthetase medium-chain family member 3 -1.61153
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 -1.60693
CD44 CD44 molecule (Indian blood group) -1.6056
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -1.60351
XPO7 exportin 7 -1.60165
TBX4 T-box 4 -1.59797
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain -1.58691
TAAR2 trace amine associated receptor 2 -1.58197
TMEM140 transmembrane protein 140 -1.58156
RLF rearranged L-myc fusion -1.57931
CCIN calicin -1.57262
SH3BP2 SH3-domain binding protein 2 -1.56678
PC pyruvate carboxylase -1.56153
CFHR4 complement factor H-related 4 -1.55851
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -1.55748
TMPRSS11D transmembrane protease, serine 11D -1.55677
HIST1H2BM histone cluster 1, H2bm -1.55459
IL9R interleukin 9 receptor -1.55409
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A -1.54922
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) -1.54542
CD163 CD163 molecule -1.54228
DIO2 deiodinase, iodothyronine, type II -1.53668
ALX4 ALX homeobox 4 -1.52804
ZNF639 zinc finger protein 639 -1.52693
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 -1.52386
BET1L Bet1 golgi vesicular membrane trafficking protein-like -1.52025
S100A11 S100 calcium binding protein A11 -1.51937
PDLIM4 PDZ and LIM domain 4 -1.51211
GPR25 G protein-coupled receptor 25 -1.50964
PDPN podoplanin -1.50735
SLC16A4 solute carrier family 16, member 4 -1.50188
NRXN2 neurexin 2 -1.49993
RAG2 recombination activating gene 2 -1.4999
ACADL acyl-CoA dehydrogenase, long chain -1.49855
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -1.49821
UBL3 ubiquitin-like 3 -1.48873
HSPB8 heat shock 22kDa protein 8 -1.48752
OR7E24 olfactory receptor, family 7, subfamily E, member 24 -1.48583
MPL MPL proto-oncogene, thrombopoietin receptor -1.47778
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -1.47073
INSR insulin receptor -1.46849
ADGRF5 adhesion G protein-coupled receptor F5 -1.46766
USP47 ubiquitin specific peptidase 47 -1.46687
ING1 inhibitor of growth family, member 1 -1.46415
PSG5 pregnancy specific beta-1-glycoprotein 5 -1.46167
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -1.46104
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) -1.45865
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa -1.45834
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 -1.45027
SETD6 SET domain containing 6 -1.44768
DAAM1 dishevelled associated activator of morphogenesis 1 -1.44665
UPB1 ureidopropionase, beta -1.44475
MTUS1 microtubule associated tumor suppressor 1 -1.43861
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -1.43634
IL12RB1 interleukin 12 receptor, beta 1 -1.43544
MYBPH myosin binding protein H -1.43089
PUM1 pumilio RNA-binding family member 1 -1.4307
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 -1.42116
CTR9 CTR9, Paf1/RNA polymerase II complex component -1.42095
RNF121 ring finger protein 121 -1.41964