NCI-H1755 Gene Set

Dataset GDSC Cell Line Gene Expression Profiles
Category transcriptomics
Type cell line
Description disease: adenocarcinoma; non-small cell lung cancer (lung primary) (Cell Line Ontology, CLO_0008016)
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Genes

205 genes with high or low expression in NCI-H1755 relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset.

high expression

Symbol Name Standardized Value
C4BPA complement component 4 binding protein, alpha 2.4231
TNIP3 TNFAIP3 interacting protein 3 2.29968
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 2.22056
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.18011
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 2.14473
G6PD glucose-6-phosphate dehydrogenase 2.09606
FGB fibrinogen beta chain 2.07837
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 2.0565
RBP4 retinol binding protein 4, plasma 2.04824
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 2.04345
MMP15 matrix metallopeptidase 15 (membrane-inserted) 2.03161
AGFG1 ArfGAP with FG repeats 1 2.00117
FGL1 fibrinogen-like 1 1.94358
PGD phosphogluconate dehydrogenase 1.92835
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 1.90853
CTNNA3 catenin (cadherin-associated protein), alpha 3 1.90331
UBE2D1 ubiquitin-conjugating enzyme E2D 1 1.90279
NME8 NME/NM23 family member 8 1.88815
HOXB8 homeobox B8 1.88436
POMC proopiomelanocortin 1.87736
FBXL18 F-box and leucine-rich repeat protein 18 1.87601
UBL4A ubiquitin-like 4A 1.86772
CXCL3 chemokine (C-X-C motif) ligand 3 1.85634
TRAF2 TNF receptor-associated factor 2 1.82114
APOB apolipoprotein B 1.81597
CRYGB crystallin, gamma B 1.8016
S100A7 S100 calcium binding protein A7 1.77141
KIAA1598 1.74961
PTGES prostaglandin E synthase 1.7464
SSX3 synovial sarcoma, X breakpoint 3 1.7446
CCL20 chemokine (C-C motif) ligand 20 1.70752
UGDH UDP-glucose 6-dehydrogenase 1.70524
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 1.70316
NECAB3 N-terminal EF-hand calcium binding protein 3 1.68536
IGFBP4 insulin-like growth factor binding protein 4 1.68059
CFB complement factor B 1.67952
TALDO1 transaldolase 1 1.66882
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 1.66078
KYNU kynureninase 1.65275
CALCA calcitonin-related polypeptide alpha 1.64591
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.64274
TKTL1 transketolase-like 1 1.63795
KIAA0319 KIAA0319 1.63619
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 1.62447
PROP1 PROP paired-like homeobox 1 1.62122
FGA fibrinogen alpha chain 1.59588
SSX2 synovial sarcoma, X breakpoint 2 1.59007
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.58219
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 1.57597
RNF17 ring finger protein 17 1.57495
CAPN15 calpain 15 1.57425
NHLRC2 NHL repeat containing 2 1.57225
S100A9 S100 calcium binding protein A9 1.56878
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 1.56872
MEGF8 multiple EGF-like-domains 8 1.56715
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 1.5642
LBP lipopolysaccharide binding protein 1.56158
TFDP3 transcription factor Dp family, member 3 1.55634
CXCL5 chemokine (C-X-C motif) ligand 5 1.55334
KRT35 keratin 35, type I 1.55241
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 1.54408
ADAP1 ArfGAP with dual PH domains 1 1.53486
TRIM17 tripartite motif containing 17 1.53244
APOH apolipoprotein H (beta-2-glycoprotein I) 1.52957
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 1.52388
OR7E19P olfactory receptor, family 7, subfamily E, member 19 pseudogene 1.51902
PDIA4 protein disulfide isomerase family A, member 4 1.51396
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.50555
CES1 carboxylesterase 1 1.50552
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 1.50461
FZD5 frizzled class receptor 5 1.50203
BMP2 bone morphogenetic protein 2 1.49808
SLC4A2 solute carrier family 4 (anion exchanger), member 2 1.48722
ZC3H12A zinc finger CCCH-type containing 12A 1.48237
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 1.46894
NXF2 nuclear RNA export factor 2 1.46315
SDF2L1 stromal cell-derived factor 2-like 1 1.46032
FADS1 fatty acid desaturase 1 1.45357
IQCE IQ motif containing E 1.4528
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.45255
GRTP1 growth hormone regulated TBC protein 1 1.45108
ZCCHC2 zinc finger, CCHC domain containing 2 1.44857
PLA2G2D phospholipase A2, group IID 1.44598
DKFZP434C153 DKFZP434C153 protein 1.44276
TMEM176A transmembrane protein 176A 1.44274
FTL ferritin, light polypeptide 1.43823
MSRB1 methionine sulfoxide reductase B1 1.4373
CPLX2 complexin 2 1.43716
NXT2 nuclear transport factor 2-like export factor 2 1.43404
LCN2 lipocalin 2 1.43372
TMEM8A transmembrane protein 8A 1.43366
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 1.4319
DGCR2 DiGeorge syndrome critical region gene 2 1.4272
TMEM176B transmembrane protein 176B 1.42676
MSMO1 methylsterol monooxygenase 1 1.42439
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 1.42331

low expression

Symbol Name Standardized Value
RFX3 regulatory factor X, 3 (influences HLA class II expression) -3.53725
ETNK1 ethanolamine kinase 1 -3.14424
TRPV6 transient receptor potential cation channel, subfamily V, member 6 -2.58592
FXR1 fragile X mental retardation, autosomal homolog 1 -2.49429
ELAC2 elaC ribonuclease Z 2 -2.4051
ELP3 elongator acetyltransferase complex subunit 3 -2.32886
SRR serine racemase -2.32626
MSX1 msh homeobox 1 -2.26694
TMEM11 transmembrane protein 11 -2.26307
BAG4 BCL2-associated athanogene 4 -2.24256
MEF2B myocyte enhancer factor 2B -2.22122
ZNF423 zinc finger protein 423 -2.1567
FKBPL FK506 binding protein like -2.15351
GSTT1 glutathione S-transferase theta 1 -2.14323
MYNN myoneurin -2.13221
CARTPT CART prepropeptide -2.13052
ORAI3 ORAI calcium release-activated calcium modulator 3 -2.07862
TBCCD1 TBCC domain containing 1 -2.07387
EDAR ectodysplasin A receptor -2.04334
MRPS22 mitochondrial ribosomal protein S22 -2.01697
GNRHR gonadotropin-releasing hormone receptor -2.01644
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -2.01327
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -1.97639
HIST1H4D histone cluster 1, H4d -1.97316
JAK2 Janus kinase 2 -1.93021
POLR1C polymerase (RNA) I polypeptide C, 30kDa -1.92895
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 -1.92835
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -1.92559
ZNF225 zinc finger protein 225 -1.91214
RFPL3 ret finger protein-like 3 -1.90768
UBE2G1 ubiquitin-conjugating enzyme E2G 1 -1.8929
BEAN1 brain expressed, associated with NEDD4, 1 -1.87621
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 -1.87321
TMEM144 transmembrane protein 144 -1.85087
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 -1.84948
RS1 retinoschisin 1 -1.84031
FOCAD focadhesin -1.83325
GTPBP3 GTP binding protein 3 (mitochondrial) -1.82263
RPA1 replication protein A1, 70kDa -1.82255
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase -1.81673
RNMTL1 RNA methyltransferase like 1 -1.79765
NUP88 nucleoporin 88kDa -1.79547
ZNF227 zinc finger protein 227 -1.78321
CCDC28A coiled-coil domain containing 28A -1.76652
CENPI centromere protein I -1.76381
MAP6D1 MAP6 domain containing 1 -1.76157
EDC3 enhancer of mRNA decapping 3 -1.75879
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 -1.75712
MAD2L1BP MAD2L1 binding protein -1.7565
MED23 mediator complex subunit 23 -1.73905
DRG1 developmentally regulated GTP binding protein 1 -1.71243
KIAA0753 KIAA0753 -1.70209
S100A13 S100 calcium binding protein A13 -1.69828
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) -1.69826
TADA2A transcriptional adaptor 2A -1.6889
RAB14 RAB14, member RAS oncogene family -1.68066
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -1.6724
ARHGAP6 Rho GTPase activating protein 6 -1.66732
FPGT fucose-1-phosphate guanylyltransferase -1.66684
HIST1H3B histone cluster 1, H3b -1.65466
CDC37L1 cell division cycle 37-like 1 -1.65214
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 -1.65069
IL12A interleukin 12A -1.64834
GLRA3 glycine receptor, alpha 3 -1.64109
DHRS7B dehydrogenase/reductase (SDR family) member 7B -1.63689
CCL22 chemokine (C-C motif) ligand 22 -1.62098
RPL35A ribosomal protein L35a -1.61721
CTNNBL1 catenin, beta like 1 -1.61498
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -1.61001
DGKE diacylglycerol kinase, epsilon 64kDa -1.60741
COPS3 COP9 signalosome subunit 3 -1.60529
CEP97 centrosomal protein 97kDa -1.58359
CSNK1G1 casein kinase 1, gamma 1 -1.56748
GPS2 G protein pathway suppressor 2 -1.56208
FAIM2 Fas apoptotic inhibitory molecule 2 -1.54998
C1QBP complement component 1, q subcomponent binding protein -1.54948
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -1.54232
ATF7IP activating transcription factor 7 interacting protein -1.53673
CDC5L cell division cycle 5-like -1.53642
COX11 COX11 cytochrome c oxidase copper chaperone -1.52553
SIGLEC15 sialic acid binding Ig-like lectin 15 -1.51882
PADI4 peptidyl arginine deiminase, type IV -1.51398
RABEP1 rabaptin, RAB GTPase binding effector protein 1 -1.50825
NIN ninein (GSK3B interacting protein) -1.49772
FICD FIC domain containing -1.48674
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -1.48646
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme -1.48469
PWP1 PWP1 homolog (S. cerevisiae) -1.48195
GHR growth hormone receptor -1.48063
ACTR5 ARP5 actin-related protein 5 homolog (yeast) -1.47473
PIGH phosphatidylinositol glycan anchor biosynthesis, class H -1.47287
SLFN12 schlafen family member 12 -1.47243
TEX10 testis expressed 10 -1.46959
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -1.46783
CAMK1D calcium/calmodulin-dependent protein kinase ID -1.44993
ZNF266 zinc finger protein 266 -1.44908
AFF4 AF4/FMR2 family, member 4 -1.44876
KLHDC3 kelch domain containing 3 -1.44702
ARMC8 armadillo repeat containing 8 -1.44446
MBTPS2 membrane-bound transcription factor peptidase, site 2 -1.44134
AZI2 5-azacytidine induced 2 -1.43771
RFXANK regulatory factor X-associated ankyrin-containing protein -1.43599
RYBP RING1 and YY1 binding protein -1.43454
BET1L Bet1 golgi vesicular membrane trafficking protein-like -1.4284
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4 -1.42492
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) -1.42327
MPDU1 mannose-P-dolichol utilization defect 1 -1.42296
KIAA0922 KIAA0922 -1.42183
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -1.41593