NCI-H1770 Gene Set

Dataset Sanger Dependency Map Cancer Cell Line Proteomics
Category proteomics
Type cell line
Description cell line derived from Non-Small Cell Lung Carcinoma Metastasis (Cell Model Passports, SIDM00737)
External Link https://cellmodelpassports.sanger.ac.uk/passports/SIDM00737
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Genes

198 proteins associated with the cell line NCI-H1770 from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

Symbol Name
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
ACOT7 acyl-CoA thioesterase 7
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
ACYP1 acylphosphatase 1, erythrocyte (common) type
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARMT1 acidic residue methyltransferase 1
BUD31 BUD31 homolog (S. cerevisiae)
C12ORF57 chromosome 12 open reading frame 57
CDC34 cell division cycle 34
CDC73 cell division cycle 73
CDK5 cyclin-dependent kinase 5
CGNL1 cingulin-like 1
CIRBP cold inducible RNA binding protein
CKB creatine kinase, brain
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CTPS1 CTP synthase 1
CTR9 CTR9, Paf1/RNA polymerase II complex component
DCXR dicarbonyl/L-xylulose reductase
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DGKE diacylglycerol kinase, epsilon 64kDa
DTNBP1 dystrobrevin binding protein 1
DUSP23 dual specificity phosphatase 23
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ENAH enabled homolog (Drosophila)
ENO2 enolase 2 (gamma, neuronal)
EPB41 erythrocyte membrane protein band 4.1
ERI3 ERI1 exoribonuclease family member 3
ESPN espin
FAF1 Fas (TNFRSF6) associated factor 1
GGCT gamma-glutamylcyclotransferase
GLCE glucuronic acid epimerase
GTF2I general transcription factor IIi
HDAC6 histone deacetylase 6
HMGN2 high mobility group nucleosomal binding domain 2
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
IRAK2 interleukin-1 receptor-associated kinase 2
KIAA1143 KIAA1143
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
LRRC40 leucine rich repeat containing 40
LRRC57 leucine rich repeat containing 57
LRRK1 leucine-rich repeat kinase 1
LUC7L2 LUC7-like 2 (S. cerevisiae)
MED8 mediator complex subunit 8
MFAP1 microfibrillar-associated protein 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MVK mevalonate kinase
NASP nuclear autoantigenic sperm protein (histone-binding)
NCAPD3 non-SMC condensin II complex, subunit D3
NECAB2 N-terminal EF-hand calcium binding protein 2
NFIA nuclear factor I/A
NLGN1 neuroligin 1
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PDS5B PDS5 cohesin associated factor B
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase
PHC2 polyhomeotic homolog 2 (Drosophila)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
PQBP1 polyglutamine binding protein 1
PRKCI protein kinase C, iota
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PUS7 pseudouridylate synthase 7 (putative)
QTRT1 queuine tRNA-ribosyltransferase 1
RBBP4 retinoblastoma binding protein 4
RBM8A RNA binding motif protein 8A
RBX1 ring-box 1, E3 ubiquitin protein ligase
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
RTN4RL2 reticulon 4 receptor-like 2
SCAF4 SR-related CTD-associated factor 4
SF3A2 splicing factor 3a, subunit 2, 66kDa
SMYD3 SET and MYND domain containing 3
SPIN1 spindlin 1
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein)
STMN1 stathmin 1
STMN2 stathmin 2
SZRD1 SUZ RNA binding domain containing 1
TARDBP TAR DNA binding protein
TMEM98 transmembrane protein 98
TRAPPC3 trafficking protein particle complex 3
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae)
TUBAL3 tubulin, alpha-like 3
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
UBA1 ubiquitin-like modifier activating enzyme 1
UBE2T ubiquitin-conjugating enzyme E2T
UBE3A ubiquitin protein ligase E3A
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
WDR81 WD repeat domain 81
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)

Symbol Name
ANO6 anoctamin 6
ANXA11 annexin A11
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
BAG2 BCL2-associated athanogene 2
BAG3 BCL2-associated athanogene 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCKDK branched chain ketoacid dehydrogenase kinase
BPIFB2 BPI fold containing family B, member 2
C17ORF49 chromosome 17 open reading frame 49
CACUL1 CDK2-associated, cullin domain 1
CCDC97 coiled-coil domain containing 97
CD276 CD276 molecule
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CRELD1 cysteine-rich with EGF-like domains 1
DDRGK1 DDRGK domain containing 1
DENND10 DENN domain containing 10
DENND2A DENN/MADD domain containing 2A
ESYT1 extended synaptotagmin-like protein 1
ETFA electron-transfer-flavoprotein, alpha polypeptide
ETFB electron-transfer-flavoprotein, beta polypeptide
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM184B family with sequence similarity 184, member B
FGF11 fibroblast growth factor 11
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GFAP glial fibrillary acidic protein
GHDC GH3 domain containing
GLTP glycolipid transfer protein
GLYCTK glycerate kinase
GRPEL1 GrpE-like 1, mitochondrial (E. coli)
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
HLTF helicase-like transcription factor
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA9 heat shock 70kDa protein 9 (mortalin)
ITSN2 intersectin 2
JUNB jun B proto-oncogene
KHK ketohexokinase (fructokinase)
KRT73 keratin 73, type II
KRT84 keratin 84, type II
LDAH lipid droplet associated hydrolase
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LGALS3 lectin, galactoside-binding, soluble, 3
LMAN2 lectin, mannose-binding 2
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MCAM melanoma cell adhesion molecule
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MESTP1 mesoderm specific transcript pseudogene 1
MREG melanoregulin
MRPL47 mitochondrial ribosomal protein L47
MRPL57 mitochondrial ribosomal protein L57
MRPS14 mitochondrial ribosomal protein S14
MSRA methionine sulfoxide reductase A
MTDH metadherin
MTERF4 mitochondrial transcription termination factor 4
MTPAP mitochondrial poly(A) polymerase
MUC16 mucin 16, cell surface associated
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NR0B1 nuclear receptor subfamily 0, group B, member 1
NUBPL nucleotide binding protein-like
NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12
OCIAD1 OCIA domain containing 1
OSBPL6 oxysterol binding protein-like 6
PEX16 peroxisomal biogenesis factor 16
PLEKHO2 pleckstrin homology domain containing, family O member 2
PNRC1 proline-rich nuclear receptor coactivator 1
PTPRJ protein tyrosine phosphatase, receptor type, J
PVR poliovirus receptor
RBMS1 RNA binding motif, single stranded interacting protein 1
RNF185 ring finger protein 185
RPS27A ribosomal protein S27a
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SGSH N-sulfoglucosamine sulfohydrolase
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SP1 Sp1 transcription factor
SSR1 signal sequence receptor, alpha
STAT5B signal transducer and activator of transcription 5B
STX10 syntaxin 10
STX4 syntaxin 4
STXBP3 syntaxin binding protein 3
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SYNGR2 synaptogyrin 2
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TEX10 testis expressed 10
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1
TMED2 transmembrane emp24 domain trafficking protein 2
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM109 transmembrane protein 109
TRUB2 TruB pseudouridine (psi) synthase family member 2
TSFM Ts translation elongation factor, mitochondrial
TTC17 tetratricopeptide repeat domain 17
TTN titin
UFL1 UFM1-specific ligase 1
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1
VDAC1 voltage-dependent anion channel 1
YES1 YES proto-oncogene 1, Src family tyrosine kinase
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFAND3 zinc finger, AN1-type domain 3
ZNF229 zinc finger protein 229